Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates JK Hobbs, W Jiao, AD Easter, EJ Parker, LA Schipper, VL Arcus ACS chemical biology 8 (11), 2388-2393, 2013 | 212 | 2013 |
Free charge photogeneration in a single component high photovoltaic efficiency organic semiconductor MB Price, PA Hume, A Ilina, I Wagner, RR Tamming, KE Thorn, W Jiao, ... Nature Communications 13 (1), 2827, 2022 | 83 | 2022 |
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis CJ Webby, W Jiao, RD Hutton, NJ Blackmore, HM Baker, EN Baker, ... Journal of biological chemistry 285 (40), 30567-30576, 2010 | 78 | 2010 |
Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design S Reichau, W Jiao, SR Walker, RD Hutton, EN Baker, EJ Parker, ... Journal of Biological Chemistry 286 (18), 16197-16207, 2011 | 59 | 2011 |
Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery W Jiao, RD Hutton, PJ Cross, GB Jameson, EJ Parker Journal of molecular biology 415 (4), 716-726, 2012 | 50 | 2012 |
Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis NJ Blackmore, S Reichau, W Jiao, RD Hutton, EN Baker, GB Jameson, ... Journal of molecular biology 425 (9), 1582-1592, 2013 | 47 | 2013 |
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2 RP Bhusal, W Jiao, BXC Kwai, J Reynisson, AJ Collins, J Sperry, ... Nature Communications 10 (1), 4639, 2019 | 30 | 2019 |
Structure of the NDH-2–HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors J Petri, Y Shimaki, W Jiao, HR Bridges, ER Russell, EJ Parker, D Aragão, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (7), 482-490, 2018 | 28 | 2018 |
Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis W Jiao, NJ Blackmore, AR Nazmi, EJ Parker PLoS ONE 12 (6), e0180052, 2017 | 21 | 2017 |
Synthesis and evaluation of dual site inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase SR Walker, W Jiao, EJ Parker Bioorganic & medicinal chemistry letters 21 (17), 5092-5097, 2011 | 20 | 2011 |
New tripeptide‐based macrocyclic calpain inhibitors formed by N‐alkylation of histidine H Chen, W Jiao, MA Jones, JM Coxon, JD Morton, R Bickerstaffe, ... Chemistry & biodiversity 9 (11), 2473-2484, 2012 | 18 | 2012 |
Using a combination of computational and experimental techniques to understand the molecular basis for protein allostery W Jiao, EJ Parker Advances in Protein Chemistry and Structural Biology 87, 391, 2012 | 17 | 2012 |
A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase G Mittelstädt, W Jiao, EK Livingstone, GJ Moggré, AR Nazmi, EJ Parker Biochemical Journal 475 (1), 247-260, 2018 | 15 | 2018 |
Crystal structure of type II NADH: quinone oxidoreductase from Caldalkalibacillus thermarum with an improved resolution of 2.15 Å Y Nakatani, W Jiao, D Aragao, Y Shimaki, J Petri, EJ Parker, GM Cook Acta Crystallographica Section F: Structural Biology Communications 73 (10), 2017 | 15 | 2017 |
Long-range exciton diffusion in a non-fullerene acceptor: approaching the incoherent limit PA Hume, W Jiao, JM Hodgkiss Journal of Materials Chemistry C 9 (4), 1419-1428, 2021 | 14 | 2021 |
A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis W Jiao, Y Fan, NJ Blackmore, EJ Parker Journal of Biological Chemistry 295 (19), 6252-6262, 2020 | 13 | 2020 |
Arg314 is essential for catalysis by N-acetyl neuraminic acid synthase from Neisseria meningitidis DDA Joseph, W Jiao, EJ Parker Biochemistry 52 (15), 2609-2619, 2013 | 12 | 2013 |
‘Tethering’fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase A Heikal, Y Nakatani, W Jiao, C Wilson, D Rennison, MR Weimar, ... Bioorganic & Medicinal Chemistry Letters 28 (13), 2239-2243, 2018 | 11 | 2018 |
Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis W Jiao, EJM Lang, Y Bai, Y Fan, EJ Parker Current Opinion in Structural Biology 65, 159-167, 2020 | 10 | 2020 |
Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis K Suthagar, W Jiao, H Munier-Lehmann, AJ Fairbanks Carbohydrate Research 457, 32-40, 2018 | 9 | 2018 |