| A network of macrophages supports mitochondrial homeostasis in the heart JA Nicolás-Ávila, AV Lechuga-Vieco, L Esteban-Martínez, ... Cell 183 (1), 94-109. e23, 2020 | 399 | 2020 |
| Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca2+-calmodulin-dependent protein kinase II J Curran, KH Brown, DJ Santiago, S Pogwizd, DM Bers, TR Shannon Journal of molecular and cellular cardiology 49 (1), 25-32, 2010 | 146 | 2010 |
| Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation J Curran, L Tang, SR Roof, S Velmurugan, A Millard, S Shonts, H Wang, ... PloS one 9 (2), e87495, 2014 | 96 | 2014 |
| Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes DJ Santiago, JW Curran, DM Bers, WJ Lederer, MD Stern, E Ríos, ... Biophysical journal 98 (10), 2111-2120, 2010 | 83 | 2010 |
| Severe cardiac dysfunction and death caused by arrhythmogenic right ventricular cardiomyopathy type 5 are improved by inhibition of glycogen synthase kinase-3β L Padrón-Barthe, M Villalba-Orero, JM Gómez-Salinero, F Domínguez, ... Circulation 140 (14), 1188-1204, 2019 | 67 | 2019 |
| Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons E Dries, DJ Santiago, G Gilbert, I Lenaerts, B Vandenberk, CK Nagaraju, ... Cardiovascular Research 114 (11), 1512-1524, 2018 | 50 | 2018 |
| A cryo-EM–based model of phosphorylation-and FKBP12. 6-mediated allosterism of the cardiac ryanodine receptor S Dhindwal, J Lobo, V Cabra, DJ Santiago, AR Nayak, K Dryden, ... Science signaling 10 (480), eaai8842, 2017 | 47 | 2017 |
| Precision Medicine in Catecholaminergic Polymorphic Ventricular Tachycardia: JACC Focus Seminar 5/5 SG Priori, A Mazzanti, DJ Santiago, D Kukavica, A Trancuccio, JC Kovacic Journal of the American College of Cardiology 77 (20), 2592-2612, 2021 | 40 | 2021 |
| Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics AV Lechuga-Vieco, A Latorre-Pellicer, IG Johnston, G Prota, U Gileadi, ... Science advances 6 (31), eaba5345, 2020 | 39 | 2020 |
| Calcium/calmodulin‐dependent kinase II and nitric oxide synthase 1‐dependent modulation of ryanodine receptors during β‐adrenergic stimulation is restricted to the dyadic cleft E Dries, DJ Santiago, DM Johnson, G Gilbert, P Holemans, SM Korte, ... The Journal of physiology 594 (20), 5923-5939, 2016 | 39 | 2016 |
| Outcomes of patients with catecholaminergic polymorphic ventricular tachycardia treated with β-blockers A Mazzanti, D Kukavica, A Trancuccio, M Memmi, R Bloise, P Gambelli, ... JAMA cardiology 7 (5), 504-512, 2022 | 29 | 2022 |
| Calcium release near L-type calcium channels promotes beat-to-beat variability in ventricular myocytes from the chronic AV block dog G Antoons, DM Johnson, E Dries, DJ Santiago, S Ozdemir, I Lenaerts, ... Journal of molecular and cellular cardiology 89, 326-334, 2015 | 25 | 2015 |
| Altered adrenergic response in myocytes bordering a chronic myocardial infarction underlies in vivo triggered activity and repolarization instability E Dries, M Amoni, B Vandenberk, DM Johnson, G Gilbert, CK Nagaraju, ... The Journal of Physiology 598 (14), 2875-2895, 2020 | 24 | 2020 |
| Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes DJ Santiago, E Ríos, TR Shannon Biophysical journal 104 (5), 976-985, 2013 | 22 | 2013 |
| The Changes in Ca2+ Sparks Associated with Measured Modifications of Intra-store Ca2+ Concentration in Skeletal Muscle BS Launikonis, J Zhou, D Santiago, G Brum, E Ríos The Journal of general physiology 128 (1), 45-54, 2006 | 22 | 2006 |
| Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant C Tzimas, DM Johnson, DJ Santiago, E Vafiadaki, DA Arvanitis, ... Cardiovascular Research 113 (11), 1403-1417, 2017 | 16 | 2017 |
| Arrhythmogenic Cardiomyopathy: Pathophysiology Beyond Cardiac Myocytes SG Priori, DJ Santiago Circulation Research 121 (12), 1296-1298, 2017 | 8 | 2017 |
| Ligand sensitivity of type-1 inositol 1, 4, 5-trisphosphate receptor is enhanced by the D2594K mutation A Tambeaux, Y Aguilar-Sánchez, DJ Santiago, M Mascitti, KM DiNovo, ... Pflügers Archiv-European Journal of Physiology 475 (5), 569-581, 2023 | 2 | 2023 |
| Altered ryanodine receptor function in ischemic heart disease: is there a role for mitochondria? DJ Santiago, E Dries, I Lenaerts, KR Sipido Biophysical Journal 108 (2), 567a, 2015 | 2 | 2015 |
| Unexpected impairment of INa underpins reentrant arrhythmias in a knock-in swine model of Timothy syndrome A Porta-Sánchez, A Mazzanti, C Tarifa, D Kukavica, A Trancuccio, ... Nature Publishing Group, 2023 | 1 | 2023 |
