| Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ... Cell reports 5 (5), 1178-1186, 2013 | 545 | 2013 |
| Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? CS Kearn, K Blake-Palmer, E Daniel, K Mackie, M Glass Molecular pharmacology 67 (5), 1697-1704, 2005 | 454 | 2005 |
| Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS BN Smith, N Ticozzi, C Fallini, AS Gkazi, S Topp, KP Kenna, EL Scotter, ... Neuron 84 (2), 324-331, 2014 | 411 | 2014 |
| TDP-43 proteinopathy and ALS: insights into disease mechanisms and therapeutic targets EL Scotter, HJ Chen, CE Shaw Neurotherapeutics 12 (2), 352-363, 2015 | 385 | 2015 |
| Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species EL Scotter, C Vance, AL Nishimura, YB Lee, HJ Chen, H Urwin, ... Journal of cell science 127 (6), 1263-1278, 2014 | 323 | 2014 |
| ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules C Vance, EL Scotter, AL Nishimura, C Troakes, JC Mitchell, C Kathe, ... Human molecular genetics 22 (13), 2676-2688, 2013 | 275 | 2013 |
| The endocannabinoid system as a target for the treatment of neurodegenerative disease EL Scotter, ME Abood, M Glass British journal of pharmacology 160 (3), 480-498, 2010 | 217 | 2010 |
| Markers for human brain pericytes and smooth muscle cells LCD Smyth, J Rustenhoven, EL Scotter, P Schweder, RLM Faull, TIH Park, ... Journal of chemical neuroanatomy 92, 48-60, 2018 | 204 | 2018 |
| TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function J Rustenhoven, M Aalderink, EL Scotter, RL Oldfield, PS Bergin, EW Mee, ... Journal of neuroinflammation 13, 1-15, 2016 | 177 | 2016 |
| The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis HJ Chen, JC Mitchell, S Novoselov, J Miller, AL Nishimura, EL Scotter, ... Brain 139 (5), 1417-1432, 2016 | 169 | 2016 |
| Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis BN Smith, SD Topp, C Fallini, H Shibata, HJ Chen, C Troakes, A King, ... Science translational medicine 9 (388), eaad9157, 2017 | 153 | 2017 |
| Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal! NL Grimsey, CE Goodfellow, EL Scotter, MJ Dowie, M Glass, ES Graham Journal of neuroscience methods 171 (1), 78-86, 2008 | 146 | 2008 |
| Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease VL Arcus, K Bäckbro, A Roos, EL Daniel, EN Baker Journal of Biological Chemistry 279 (16), 16471-16478, 2004 | 140 | 2004 |
| PU. 1 regulates Alzheimer’s disease-associated genes in primary human microglia J Rustenhoven, AM Smith, LC Smyth, D Jansson, EL Scotter, ... Molecular neurodegeneration 13, 1-16, 2018 | 119 | 2018 |
| Novel mutations support a role for Profilin 1 in the pathogenesis of ALS BN Smith, C Vance, EL Scotter, C Troakes, CH Wong, S Topp, ... Neurobiology of aging 36 (3), 1602. e17-1602. e27, 2015 | 115 | 2015 |
| Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS JC Mitchell, R Constable, E So, C Vance, E Scotter, L Glover, ... Acta neuropathologica communications 3, 1-16, 2015 | 99 | 2015 |
| Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease EL Scotter, CE Goodfellow, ES Graham, M Dragunow, M Glass British journal of pharmacology 160 (3), 747-761, 2010 | 74 | 2010 |
| Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase … ES Graham, N Ball, EL Scotter, P Narayan, M Dragunow, M Glass Journal of biological chemistry 281 (39), 29085-29095, 2006 | 69 | 2006 |
| Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis R Dewan, R Chia, J Ding, RA Hickman, TD Stein, Y Abramzon, S Ahmed, ... Neuron 109 (3), 448-460. e4, 2021 | 66 | 2021 |
| ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function JJ Wu, A Cai, JE Greenslade, NR Higgins, C Fan, NTT Le, M Tatman, ... Proceedings of the National Academy of Sciences 117 (26), 15230-15241, 2020 | 66 | 2020 |
