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Aaron G Dale
Aaron G Dale
Graduate Medical Student, Oxford University
Verified email at medschool.ox.ac.uk
Title
Cited by
Cited by
Year
Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells
M Micco, GW Collie, AG Dale, SA Ohnmacht, I Pazitna, M Gunaratnam, ...
Journal of medicinal chemistry 56 (7), 2959-2974, 2013
1922013
Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule
SJ Welsh, AG Dale, CM Lombardo, H Valentine, M de La Fuente, ...
Scientific reports 3 (1), 2799, 2013
432013
A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines
CM Lombardo, SJ Welsh, SJ Strauss, AG Dale, AK Todd, R Nanjunda, ...
Bioorganic & medicinal chemistry letters 22 (18), 5984-5988, 2012
392012
Symmetric bis-benzimidazoles are potent anti-staphylococcal agents with dual inhibitory mechanisms against DNA gyrase
AG Dale, J Hinds, J Mann, PW Taylor, S Neidle
Biochemistry 51 (29), 5860-5871, 2012
312012
The discovery of a novel antibiotic for the treatment of Clostridium difficile infections: a story of an effective academic–industrial partnership
J Mann, PW Taylor, CR Dorgan, PD Johnson, FX Wilson, R Vickers, ...
Medchemcomm 6 (8), 1420-1426, 2015
302015
The ectopically parting cells 1-2 (epc1-2) mutant exhibits an exaggerated response to abscisic acid
L Bown, S Kusaba, F Goubet, L Codrai, AG Dale, Z Zhang, X Yu, K Morris, ...
Journal of experimental botany 58 (7), 1813-1823, 2007
262007
Increased toxin expression in a Clostridium difficile mfd mutant
SE Willing, EJ Richards, L Sempere, AG Dale, SM Cutting, ...
BMC microbiology 15, 1-10, 2015
232015
The mechanism of resistance in Escherichia coli to ridinilazole and other antibacterial head-to-head bis-benzimidazole compounds
AG Dale, A Porcu, J Mann, S Neidle
Medicinal Chemistry Research 31 (7), 1176-1191, 2022
22022
Diimide compounds
S Neidle, SA Ohnmacht, M Gunaratnam, AG Dale, M Micco, GW Collie
US Patent 9,493,460, 2016
2016
Elucidating the molecular target of symmetric bis-benzimidazoles
AG Dale
PQDT-Global, 2011
2011
Broadening the field of opportunity for medicinal chemists www. rsc. org/medchemcomm
J Mann, PW Taylor, CR Dorgan, PD Johnson, FX Wilson, R Vickers, ...
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