Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families SA Shah, OS Alkhnbashi, J Behler, W Han, Q She, WR Hess, RA Garrett, ... RNA biology 16 (4), 530-542, 2019 | 91 | 2019 |
A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction W Han, Y Li, L Deng, M Feng, W Peng, S Hallstrøm, J Zhang, N Peng, ... Nucleic acids research 45 (4), 1983-1993, 2017 | 87 | 2017 |
A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding W Han, S Stella, Y Zhang, T Guo, K Sulek, L Peng-Lundgren, G Montoya, ... Nucleic acids research 46 (19), 10319-10330, 2018 | 57 | 2018 |
Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea N Peng, W Han, Y Li, Y Liang, Q She Science China Life Sciences 60, 370-385, 2017 | 54 | 2017 |
CRISPR history: discovery, characterization, and prosperity W Han, Q She Progress in molecular biology and translational science 152, 1-21, 2017 | 49 | 2017 |
A short prokaryotic Argonaute activates membrane effector to confer antiviral defense Z Zeng, Y Chen, R Pinilla-Redondo, SA Shah, F Zhao, C Wang, Z Hu, ... Cell host & microbe 30 (7), 930-943. e6, 2022 | 36 | 2022 |
Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail W Han, S Pan, B Lopez-Mendez, G Montoya, Q She Nucleic acids research 45 (18), 10740-10750, 2017 | 35 | 2017 |
An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea M Sun, X Feng, Z Liu, W Han, YX Liang, Q She Nucleic acids research 46 (13), 6697-6711, 2018 | 33 | 2018 |
Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA Y Li, Y Zhang, J Lin, S Pan, W Han, N Peng, YX Liang, Q She Nucleic acids research 45 (19), 11305-11314, 2017 | 28 | 2017 |
A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea X Feng, M Sun, W Han, YX Liang, Q She Nucleic acids research 46 (14), 7085-7096, 2018 | 25 | 2018 |
Reverse gyrase functions in genome integrity maintenance by protecting DNA breaks in vivo W Han, X Feng, Q She International Journal of Molecular Sciences 18 (7), 1340, 2017 | 25 | 2017 |
Knockouts of RecA-like proteins RadC1 and RadC2 have distinct responses to DNA damage agents in Sulfolobus islandicus PJ Liang, WY Han, QH Huang, YZ Li, JF Ni, QX She, YL Shen Journal of genetics and genomics 40 (10), 533-542, 2013 | 22 | 2013 |
Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus T Guo, W Han, Q She RNA biology 16 (4), 549-556, 2019 | 21 | 2019 |
NQO-Induced DNA-Less Cell Formation Is Associated with Chromatin Protein Degradation and Dependent on A0A1-ATPase in Sulfolobus W Han, Y Xu, X Feng, YX Liang, L Huang, Y Shen, Q She Frontiers in microbiology 8, 1480, 2017 | 20 | 2017 |
In vivo and in vitro protein imaging in thermophilic archaea by exploiting a novel protein tag V Visone, W Han, G Perugino, G Del Monaco, Q She, M Rossi, A Valenti, ... PLoS One 12 (10), e0185791, 2017 | 19 | 2017 |
An archaeal protein evolutionarily conserved in prokaryotes is a zinc-dependent metalloprotease Y Hu, N Peng, W Han, Y Mei, Z Chen, X Feng, YX Liang, Q She Bioscience Reports 32 (6), 609-618, 2012 | 16 | 2012 |
Single-stranded DNA binding activity of XPBI, but not XPBII, from Sulfolobus tokodaii causes double-stranded DNA melting X Ma, Y Hong, W Han, D Sheng, J Ni, G Hou, Y Shen Extremophiles 15, 67-76, 2011 | 16 | 2011 |
A membrane-associated DHH-DHHA1 nuclease degrades type III CRISPR second messenger R Zhao, Y Yang, F Zheng, Z Zeng, W Feng, X Jin, J Wang, K Yang, ... Cell Reports 32 (11), 2020 | 13 | 2020 |
A unique B-Family DNA polymerase facilitating error-prone DNA damage tolerance in crenarchaeota X Feng, X Liu, R Xu, R Zhao, W Feng, J Liao, W Han, Q She Frontiers in Microbiology 11, 1585, 2020 | 13 | 2020 |
Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system T Guo, F Zheng, Z Zeng, Y Yang, Q Li, Q She, W Han RNA biology 16 (10), 1513-1520, 2019 | 13 | 2019 |