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David Briles
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Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae.
DE Briles, M Nahm, K Schroer, J Davie, P Baker, J Kearney, R Barletta
The Journal of experimental medicine 153 (3), 694-705, 1981
5911981
Subclass restriction of murine anti-carbohydrate antibodies
RM Perlmutter, D Hansburg, DE Briles, RA Nicolotti, JM David
The Journal of Immunology 121 (2), 566-572, 1978
5451978
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae
AM Berry, J Yother, DE Briles, D Hansman, JC Paton
Infection and immunity 57 (7), 2037-2042, 1989
4501989
Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae
SK Hollingshead, R Becker, DE Briles
Infection and immunity 68 (10), 5889-5900, 2000
4222000
Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae
AHT Tu, RL Fulgham, MA McCrory, DE Briles, AJ Szalai
Infection and immunity 67 (9), 4720-4724, 1999
4181999
Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae
DE Briles, E Ades, JC Paton, JS Sampson, GM Carlone, RC Huebner, ...
Infection and immunity 68 (2), 796-800, 2000
3832000
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.
DE Briles, C Forman, S Hudak, JL Claflin
The Journal of experimental medicine 156 (4), 1177-1185, 1982
3791982
Basophils enhance immunological memory responses
A Denzel, UA Maus, MR Gomez, C Moll, M Niedermeier, C Winter, ...
Nature immunology 9 (7), 733-742, 2008
3552008
Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae
DE Briles, MJ Crain, BM Gray, C Forman, J Yother
Infection and immunity 60 (1), 111-116, 1992
3481992
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae
MJ Crain, WD Waltman 2nd, JS Turner, J Yother, DF Talkington, ...
Infection and immunity 58 (10), 3293-3299, 1990
3471990
The pspC Gene of Streptococcus pneumoniae Encodes a Polymorphic Protein, PspC, Which Elicits Cross-Reactive Antibodies to PspA and Provides Immunity to …
A Brooks-Walter, DE Briles, SK Hollingshead
Infection and immunity 67 (12), 6533-6542, 1999
3291999
PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type
LS McDANIEL, JS Sheffield, P Delucchi, DE Briles
Infection and immunity 59 (1), 222-228, 1991
3021991
Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae
HY Wu, MH Nahm, Y Guo, MW Russell, DE Briles
Journal of Infectious Diseases 175 (4), 839-846, 1997
2971997
PspA Protects Streptococcus pneumoniae from Killing by Apolactoferrin, and Antibody to PspA Enhances Killing of Pneumococci by Apolactoferrin
M Shaper, SK Hollingshead, WH Benjamin Jr, DE Briles
Infection and immunity 72 (9), 5031-5040, 2004
2902004
Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae …
DE Briles, SK Hollingshead, J King, A Swift, PA Braun, MK Park, ...
The Journal of infectious diseases 182 (6), 1694-1701, 2000
2852000
Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice.
AJ Szalai, DE Briles, JE Volanakis
Journal of immunology (Baltimore, Md.: 1950) 155 (5), 2557-2563, 1995
2841995
Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae
DE Briles, SK Hollingshead, JC Paton, EW Ades, L Novak, FW van Ginkel, ...
The Journal of infectious diseases 188 (3), 339-348, 2003
2802003
Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis
J Yother, DE Briles
Journal of bacteriology 174 (2), 601-609, 1992
2771992
Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA).
LS McDANIEL, J Yother, M Vijayakumar, L McGARRY, WR Guild, ...
The Journal of experimental medicine 165 (2), 381-394, 1987
2721987
Development of a Vaccine against Invasive Pneumococcal Disease Based on Combinations of Virulence Proteins of Streptococcus pneumoniae
AD Ogunniyi, M Grabowicz, DE Briles, J Cook, JC Paton
Infection and immunity 75 (1), 350-357, 2007
2702007
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