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Malcolm Irving
Malcolm Irving
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size
G Piazzesi, M Reconditi, M Linari, L Lucii, P Bianco, E Brunello, ...
Cell 131 (4), 784-795, 2007
3632007
Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments
M Linari, E Brunello, M Reconditi, L Fusi, M Caremani, T Narayanan, ...
Nature 528 (7581), 276-279, 2015
2962015
Myosin head movements are synchronous with the elementary force-generating process in muscle
M Irving, V Lombardi, G Piazzesi, MA Ferenczi
Nature 357 (6374), 156-158, 1992
2511992
Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction
JET Corrie, BD Brandmeier, RE Ferguson, DR Trentham, ...
Nature 400 (6743), 425-430, 1999
2501999
Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle
M Irving, T St Claire Alien, C Sabido-David, JS Craik, B Brandmeier, ...
Nature 375 (6533), 688-691, 1995
2361995
The myosin motor in muscle generates a smaller and slower working stroke at higher load
M Reconditi, M Linari, L Lucii, A Stewart, YB Sun, P Boesecke, ...
Nature 428 (6982), 578-581, 2004
2322004
The stiffness of skeletal muscle in isometric contraction and rigor: the fraction of myosin heads bound to actin
M Linari, I Dobbie, M Reconditi, N Koubassova, M Irving, G Piazzesi, ...
Biophysical journal 74 (5), 2459-2473, 1998
2121998
Elastic bending and active tilting of myosin heads during muscle contraction
I Dobbie, M Linari, G Piazzesi, M Reconditi, N Koubassova, MA Ferenczi, ...
Nature 396 (6709), 383-387, 1998
1911998
Mechanism of force generation by myosin heads in skeletal muscle
G Piazzesi, M Reconditi, M Linari, L Lucii, YB Sun, T Narayanan, ...
Nature 415 (6872), 659-662, 2002
1872002
Regulation of contraction by the thick filaments in skeletal muscle
M Irving
Biophysical journal 113 (12), 2579-2594, 2017
1652017
Elastic distortion of myosin heads and repriming of the working stroke in muscle
V Lombard, G Piazzesi, MA Ferenczi, H Thirlwell, I Dobbie, M Irving
Nature 374 (6522), 553-555, 1995
1451995
Skeletal muscle resists stretch by rapid binding of the second motor domain of myosin to actin
E Brunello, M Reconditi, R Elangovan, M Linari, YB Sun, T Narayanan, ...
Proceedings of the National Academy of Sciences 104 (50), 20114-20119, 2007
1392007
Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments
T Kampourakis, YB Sun, M Irving
Proceedings of the National Academy of Sciences 113 (21), E3039-E3047, 2016
1352016
Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells
T Kampourakis, Z Yan, M Gautel, YB Sun, M Irving
Proceedings of the National Academy of Sciences 111 (52), 18763-18768, 2014
1332014
Conformation of the myosin motor during force generation in skeletal muscle
M Irving, G Piazzesi, L Lucii, YB Sun, JJ Harford, IM Dobbie, MA Ferenczi, ...
Nature structural biology 7 (6), 482-485, 2000
1332000
Interference fine structure and sarcomere length dependence of the axial x-ray pattern from active single muscle fibers
M Linari, G Piazzesi, I Dobbie, N Koubassova, M Reconditi, T Narayanan, ...
Proceedings of the National Academy of Sciences 97 (13), 7226-7231, 2000
1312000
Calcium‐and myosin‐dependent changes in troponin structure during activation of heart muscle
YB Sun, F Lou, M Irving
The Journal of Physiology 587 (1), 155-163, 2009
1172009
Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle
L Fusi, E Brunello, Z Yan, M Irving
Nature communications 7 (1), 13281, 2016
1142016
Myosin filament-based regulation of the dynamics of contraction in heart muscle
E Brunello, L Fusi, A Ghisleni, SJ Park-Holohan, JG Ovejero, ...
Proceedings of the National Academy of Sciences 117 (14), 8177-8186, 2020
1092020
Fluorescence polarization transients from rhodamine isomers on the myosin regulatory light chain in skeletal muscle fibers
SC Hopkins, C Sabido-David, JET Corrie, M Irving, YE Goldman
Biophysical journal 74 (6), 3093-3110, 1998
1071998
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