Nicole E Wheeler
Nicole E Wheeler
Data Scientist, Wellcome Sanger Institute
Verified email at sanger.ac.uk
Title
Cited by
Cited by
Year
Convergent regulatory evolution and loss of flight in paleognathous birds
TB Sackton, P Grayson, A Cloutier, Z Hu, JS Liu, NE Wheeler, PP Gardner, ...
Science 364 (6435), 74-78, 2019
72*2019
Robust identification of noncoding RNA from transcriptomes requires phylogenetically-informed sampling
S Lindgreen, SU Umu, ASW Lai, H Eldai, W Liu, S McGimpsey, ...
PLoS Comput Biol 10 (10), e1003907, 2014
352014
Why so narrow: distribution of anti-sense regulated, type I toxin-antitoxin systems compared with type II and type III systems
DS Coray, NE Wheeler, JA Heinemann, PP Gardner
RNA biology 14 (3), 275-280, 2017
242017
Machine learning identifies signatures of host adaptation in the bacterial pathogen Salmonella enterica
NE Wheeler, PP Gardner, L Barquist
PLoS genetics 14 (5), e1007333, 2018
232018
Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data
AL Hicks, N Wheeler, L Sánchez-Busó, JL Rakeman, SR Harris, YH Grad
PLoS computational biology 15 (9), e1007349, 2019
172019
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
JA Lees, B Ferwerda, PHC Kremer, NE Wheeler, MV Serón, NJ Croucher, ...
Nature communications 10 (1), 1-14, 2019
142019
A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes
NE Wheeler, L Barquist, RA Kingsley, PP Gardner
Bioinformatics 32 (23), 3566-3574, 2016
142016
Tracing outbreaks with machine learning
NE Wheeler
Nature Reviews Microbiology 17 (5), 269, 2019
102019
Breaking the code of antibiotic resistance
SW Lo, N Kumar, NE Wheeler
Nature Reviews Microbiology 16 (5), 262-262, 2018
82018
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
S Van Puyvelde, D Pickard, K Vandelannoote, E Heinz, B Barbé, ...
Nature communications 10 (1), 1-12, 2019
72019
Increased power from bacterial genome-wide association conditional on known effects identifies Neisseria gonorrhoeae macrolide resistance mutations in the 50S ribosomal protein L4
KC Ma, TD Mortimer, MA Duckett, AL Hicks, NE Wheeler, L Sánchez-Busó, ...
BioRxiv, 2020
22020
Genomic correlates of extraintestinal infection are linked with changes in cell morphology in Campylobacter jejuni
NE Wheeler, T Blackmore, AD Reynolds, AC Midwinter, J Marshall, ...
Microbial genomics 5 (2), 2019
22019
Improved inference and prediction of bacterial genotype-phenotype associations using pangenome-spanning regressions
JA Lees, TT Mai, M Galardini, NE Wheeler, J Corander
BioRxiv, 852426, 2019
22019
Genomic, transcriptomic, and phenotypic analyses of Neisseria meningitidis isolates from disease patients and their household contacts
X Ren, DA Eccles, GA Greig, J Clapham, NE Wheeler, S Lindgreen, ...
Msystems 2 (6), 2017
22017
Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment
KC Ma, TD Mortimer, AL Hicks, NE Wheeler, L Sánchez-Busó, ...
BioRxiv, 2020
12020
We are falling behind on TB elimination targets: can whole-genome sequencing guide our efforts?
N Wheeler
Thorax 74 (9), 833-834, 2019
12019
Contrasting approaches to genome-wide association studies impact the detection of resistance mechanisms in Staphylococcus aureus
NE Wheeler, S Reuter, C Chewapreecha, JA Lees, B Blane, C Horner, ...
BioRxiv, 758144, 2019
12019
Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions
JA Lees, TT Mai, M Galardini, NE Wheeler, ST Horsfield, J Parkhill, ...
Mbio 11 (4), 2020
2020
Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation
M Bawn, NF Alikhan, G Thilliez, M Kirkwood, NE Wheeler, L Petrovska, ...
Plos Genetics 16 (6), e1008850, 2020
2020
ALTERNATIVE TRANSMISSION PATHWAYS OF MYCOBACTERIUM ABSCESSUS GROUP (MABS) RESPIRATORY INFECTIONS
R Stockwell, L Leong, N Wheeler, J Bryant, M Wood, L Sherrard, ...
Respirology 25, 22-22, 2020
2020
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Articles 1–20