Nicole E Wheeler
Nicole E Wheeler
Data Scientist, Wellcome Sanger Institute
Verified email at sanger.ac.uk
TitleCited byYear
Convergent regulatory evolution and loss of flight in paleognathous birds
TB Sackton, P Grayson, A Cloutier, Z Hu, JS Liu, NE Wheeler, PP Gardner, ...
Science 364 (6435), 74-78, 2019
35*2019
Robust identification of noncoding RNA from transcriptomes requires phylogenetically-informed sampling
S Lindgreen, SU Umu, ASW Lai, H Eldai, W Liu, S McGimpsey, ...
PLoS computational biology 10 (10), e1003907, 2014
302014
Machine learning identifies signatures of host adaptation in the bacterial pathogen Salmonella enterica
NE Wheeler, PP Gardner, L Barquist
PLoS genetics 14 (5), e1007333, 2018
152018
A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes
NE Wheeler, L Barquist, RA Kingsley, PP Gardner
Bioinformatics 32 (23), 3566-3574, 2016
142016
Why so narrow: distribution of anti-sense regulated, type I toxin-antitoxin systems compared with type II and type III systems
DS Coray, NE Wheeler, JA Heinemann, PP Gardner
RNA biology 14 (3), 275-280, 2017
102017
Breaking the code of antibiotic resistance
SW Lo, N Kumar, NE Wheeler
Nature Reviews Microbiology 16 (5), 262, 2018
62018
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
JA Lees, B Ferwerda, PHC Kremer, NE Wheeler, MV Serón, NJ Croucher, ...
Nature communications 10 (1), 2176, 2019
52019
Tracing outbreaks with machine learning
NE Wheeler
Nature Reviews Microbiology 17 (5), 269, 2019
42019
Genomic, Transcriptomic, and Phenotypic Analyses of Neisseria meningitidis Isolates from Disease Patients and Their Household Contacts
X Ren, DA Eccles, GA Greig, J Clapham, NE Wheeler, S Lindgreen, ...
MSystems 2 (6), e00127-17, 2017
22017
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
S Van Puyvelde, D Pickard, K Vandelannoote, E Heinz, B Barbé, ...
Nature communications 10 (1), 1-12, 2019
12019
Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data
AL Hicks, N Wheeler, L Sanchez-Buso, JL Rakeman, SR Harris, YH Grad
bioRxiv, 607127, 2019
12019
MYCOBACTERIUM ABSCESSUS POINT SOURCE OUTBREAK IN THE LOCAL POTABLE WATER SUPPLY AFFECTING PEOPLE WITH CYSTIC FIBROSIS
RE Stockwell, R Thomson, LE Leong, NE Wheeler, J Bryant, ME Wood, ...
Pediatric Pulmonology 54, S300-S300, 2019
2019
We are falling behind on TB elimination targets: can whole-genome sequencing guide our efforts?
N Wheeler
Thorax 74 (9), 833-834, 2019
2019
POTABLE WATER AS A POSSIBLE SOURCE OF MYCOBACTERIUM ABSCESSUS INFECTION IN PEOPLE WITH CHRONIC LUNG CONDITIONS
R Stockwell, L Leong, N Wheeler, J Bryant, M Wood, L Sherrard, ...
RESPIROLOGY 24, 42-42, 2019
2019
Genomic correlates of extraintestinal infection are linked with changes in cell morphology in Campylobacter jejuni
NE Wheeler, T Blackmore, AD Reynolds, AC Midwinter, J Marshall, ...
Microbial genomics 5 (2), 2019
2019
Improved inference and prediction of bacterial genotype-phenotype associations using pangenome-spanning regressions
JA Lees, TT Mai, M Galardini, NE Wheeler, J Corander
BioRxiv, 852426, 2019
2019
Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation
M Bawn, G Thilliez, M Kirkwood, N Wheeler, L Petrovska, TJ Dallman, ...
bioRxiv, 804674, 2019
2019
Contrasting approaches to genome-wide association studies impact the detection of resistance mechanisms in Staphylococcus aureus
NE Wheeler, S Reuter, C Chewapreecha, JA Lees, B Blane, C Horner, ...
BioRxiv, 758144, 2019
2019
PREVALENCE OF SHARED MYCOBACTERIUM ABSCESSUS COMPLEX IN THE QUEENSLAND CYSTIC FIBROSIS POPULATION
RE Stockwell, L Leong, N Wheeler, J Bryant, ME Wood, L Sherrard, ...
PEDIATRIC PULMONOLOGY 53, 283-283, 2018
2018
Genetic risk variants for heart failure onset and progression do not improve prediction of mortality beyond established prognostic neurohormonal and echocardiographic markers …
A Pilbrow, E Templeton, G Gamble, N Wheeler, C Frampton, J Pearson, ...
European Heart Journal 39, 2018
2018
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Articles 1–20