Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ... The Journal of immunology 186 (6), 3299-3303, 2011 | 2065 | 2011 |
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function AN Macintyre, VA Gerriets, AG Nichols, RD Michalek, MC Rudolph, ... Cell metabolism 20 (1), 61-72, 2014 | 1086 | 2014 |
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 668 | 2015 |
Metabolic pathways in T cell fate and function VA Gerriets, JC Rathmell Trends in immunology 33 (4), 168-173, 2012 | 475 | 2012 |
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ... Nature immunology 17 (12), 1459-1466, 2016 | 472 | 2016 |
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability A Huynh, M DuPage, B Priyadharshini, PT Sage, J Quiros, CM Borges, ... Nature immunology 16 (2), 188-196, 2015 | 415 | 2015 |
Leptin metabolically licenses T cells for activation to link nutrition and immunity DC Saucillo, VA Gerriets, J Sheng, JC Rathmell, NJ MacIver The Journal of Immunology 192 (1), 136-144, 2014 | 271 | 2014 |
Beyond a neurotransmitter: The role of serotonin in inflammation and immunity H Wu, TH Denna, JN Storkersen, VA Gerriets Pharmacological research 140, 100-114, 2019 | 257 | 2019 |
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation RD Michalek, VA Gerriets, AG Nichols, M Inoue, D Kazmin, CY Chang, ... Proceedings of the National Academy of Sciences 108 (45), 18348-18353, 2011 | 235 | 2011 |
AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival RJ Kishton, CE Barnes, AG Nichols, S Cohen, VA Gerriets, PJ Siska, ... Cell metabolism 23 (4), 649-662, 2016 | 226 | 2016 |
Role of T cells in malnutrition and obesity VA Gerriets, NJ MacIver Frontiers in Immunology 5, 105102, 2014 | 160 | 2014 |
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells JL Coloff, EF Mason, BJ Altman, VA Gerriets, T Liu, AN Nichols, Y Zhao, ... Journal of Biological Chemistry 286 (7), 5921-5933, 2011 | 118 | 2011 |
Leptin directly promotes T‐cell glycolytic metabolism to drive effector T‐cell differentiation in a mouse model of autoimmunity VA Gerriets, K Danzaki, RJ Kishton, W Eisner, AG Nichols, DC Saucillo, ... European journal of immunology 46 (8), 1970-1983, 2016 | 114 | 2016 |
The TviA auxiliary protein renders the Salmonella enterica serotype Typhi RcsB regulon responsive to changes in osmolarity SE Winter, MG Winter, P Thiennimitr, VA Gerriets, SP Nuccio, ... Molecular microbiology 74 (1), 175-193, 2009 | 98 | 2009 |
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis T Liu, RJ Kishton, AN Macintyre, VA Gerriets, H Xiang, X Liu, ED Abel, ... Cell death & disease 5 (10), e1470-e1470, 2014 | 81 | 2014 |
Cutting edge: TGF-β and phosphatidylinositol 3-kinase signals modulate distinct metabolism of regulatory T cell subsets B Priyadharshini, M Loschi, RH Newton, JW Zhang, KK Finn, VA Gerriets, ... The Journal of Immunology 201 (8), 2215-2219, 2018 | 67 | 2018 |
Matched and mismatched metabolic fuels in lymphocyte function A Caro-Maldonado, VA Gerriets, JC Rathmell Seminars in immunology 24 (6), 405-413, 2012 | 46 | 2012 |
CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism H Wu, DV Herr, NJ MacIver, JC Rathmell, VA Gerriets International immunopharmacology 88, 106922, 2020 | 22 | 2020 |
Targeting in vivo metabolic vulnerabilities of Th2 and Th17 cells reduces airway inflammation DCC Healey, JY Cephus, SM Barone, NU Chowdhury, DO Dahunsi, ... The Journal of Immunology 206 (6), 1127-1139, 2021 | 18 | 2021 |
Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice M Gong, SC Choi, YP Park, X Zou, AS Elshikha, VA Gerriets, JC Rathmell, ... Iscience 26 (5), 2023 | 5 | 2023 |