Plamena R. Angelova
Plamena R. Angelova
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Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
PR Angelova, AY Abramov
FEBS letters 592 (5), 692-702, 2018
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
S Kovac, PR Angelova, KM Holmstr÷m, Y Zhang, AT Dinkova-Kostova, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, ...
Nature communications 9 (1), 2293, 2018
Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease
E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, ...
Antioxidants & redox signaling 24 (7), 376-391, 2016
Functional oxygen sensitivity of astrocytes
PR Angelova, V Kasymov, I Christie, S Sheikhbahaei, E Turovsky, ...
Journal of Neuroscience 35 (29), 10460-10473, 2015
Functional role of mitochondrial reactive oxygen species in physiology
PR Angelova, AY Abramov
Free radical biology and medicine 100, 81-85, 2016
Nrf2 affects the efficiency of mitochondrial fatty acid oxidation
MHR Ludtmann, PR Angelova, Y Zhang, AY Abramov, ...
Biochemical Journal 457 (3), 415-424, 2014
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
WY Sun, VA Tyurin, K Mikulska-Ruminska, IH Shrivastava, ...
Nature chemical biology 17 (4), 465-476, 2021
Ca2+ is a key factor in α-synuclein-induced neurotoxicity
PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, ...
Journal of cell science 129 (9), 1792-1801, 2016
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, ...
Cell Death & Differentiation 27 (10), 2781-2796, 2020
Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention
PR Angelova, N Esteras, AY Abramov
Medicinal Research Reviews 41 (2), 770-784, 2021
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ...
Brain 138 (7), 1801-1816, 2015
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons
AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, ...
Cell death & disease 6 (7), e1820-e1820, 2015
Monomeric alpha-synuclein exerts a physiological role on brain ATP synthase
MHR Ludtmann, PR Angelova, NN Ninkina, S Gandhi, VL Buchman, ...
Journal of Neuroscience 36 (41), 10510-10521, 2016
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease
R Tufi, S Gandhi, IP De Castro, S Lehmann, PR Angelova, D Dinsdale, ...
Nature cell biology 16 (2), 157-166, 2014
Lipid peroxidation is essential for α‐synuclein‐induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, ...
Journal of neurochemistry 133 (4), 582-589, 2015
Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury
HK Siddall, DM Yellon, SB Ong, UA Mukherjee, N Burke, AR Hall, ...
PloS one 8 (4), e62400, 2013
'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia'
R Abeti, MH Parkinson, IP Hargreaves, PR Angelova, C Sandi, MA Pook, ...
Cell death & disease 7 (5), e2237-e2237, 2016
Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation
PR Angelova, M Barilani, C Lovejoy, M Dossena, M Vigan˛, A Seresini, ...
Redox biology 14, 474-484, 2018
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, ...
Nature neuroscience 25 (9), 1134-1148, 2022
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