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| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4362 | 2020 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 613 | 2020 |
| Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase KA Verba, RYR Wang, A Arakawa, Y Liu, M Shirouzu, S Yokoyama, ... Science 352 (6293), 1542-1547, 2016 | 412 | 2016 |
| How Hsp90 and Cdc37 lubricate kinase molecular switches KA Verba, DA Agard Trends in biochemical sciences 42 (10), 799-811, 2017 | 89 | 2017 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 70 | 2021 |
| Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity TO Street, LA Lavery, KA Verba, CT Lee, MP Mayer, DA Agard Journal of molecular biology 415 (1), 3-15, 2012 | 62 | 2012 |
| Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface D Diwanji, R Trenker, TM Thaker, F Wang, DA Agard, KA Verba, N Jura Nature 600 (7888), 339-343, 2021 | 56 | 2021 |
| Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM M Sun, CM Azumaya, E Tse, DP Bulkley, MB Harrington, G Gilbert, A Frost, ... Journal of structural biology 213 (3), 107745, 2021 | 42 | 2021 |
| Drugging the “undruggable” MYCN oncogenic transcription factor: overcoming previous obstacles to impact childhood cancers AJ Wolpaw, R Bayliss, G Büchel, CV Dang, M Eilers, WC Gustafson, ... Cancer research 81 (7), 1627-1632, 2021 | 33 | 2021 |
| SARS-CoV-2 variants evolve convergent strategies to remodel the host response M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ... Cell 186 (21), 4597-4614. e26, 2023 | 21 | 2023 |
| Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ... bioRxiv, 2022.10. 19.512927, 2022 | 8 | 2022 |
| Atomic structure of Hsp90: Cdc37: Cdk4 reveals Hsp90 regulates kinase via dramatic unfolding KA Verba, RYR Wang, A Arakawa, Y Liu, M Shirouzu, S Yokoyama, ... Science (New York, NY) 352 (6293), 1542, 2016 | 6 | 2016 |
| Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3 CE Peters, U Schulze-Gahmen, M Eckhardt, GM Jang, J Xu, EH Pulido, ... Nature communications 13 (1), 5282, 2022 | 5 | 2022 |
| Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps SG Remesh, GE Merz, AF Brilot, US Chio, AN Rizo, TH Pospiech, I Lui, ... Structure 31 (3), 253-264. e6, 2023 | 4 | 2023 |
| Protein expression and purification of the Hsp90-Cdc37-Cdk4 kinase complex from Saccharomyces cerevisiae KA Verba, DA Agard Bio-protocol 7 (19), e2563-e2563, 2017 | 4 | 2017 |
| Structures of the active HER2/HER3 receptor complex reveal dynamics at the dimerization interface induced by binding of a single ligand D Diwanji, R Trenker, TM Thaker, F Wang, DA Agard, KA Verba, N Jura bioRxiv, 2021.05. 03.442258, 2021 | 3 | 2021 |
| A SARS-CoV-2-Human protein-Protein interaction map reveals drug targets and potential drug-repurposing (preprint) DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, JZ Guo, ... | 3 | 2020 |
| Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4 X Zhou, S Kong, A Maker, SG Remesh, KK Leung, KA Verba, JA Wells Nature Chemical Biology, 1-9, 2024 | 2 | 2024 |
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