Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus MA Cowley, JL Smart, M Rubinstein, MG Cerdán, S Diano, TL Horvath, ... Nature 411 (6836), 480-484, 2001 | 2872 | 2001 |
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis MA Cowley, RG Smith, S Diano, M Tschöp, N Pronchuk, KL Grove, ... Neuron 37 (4), 649-661, 2003 | 2155 | 2003 |
Rapid rewiring of arcuate nucleus feeding circuits by leptin S Pinto, AG Roseberry, H Liu, S Diano, M Shanabrough, X Cai, ... science 304 (5667), 110-115, 2004 | 1139 | 2004 |
Ghrelin TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ... Molecular metabolism 4 (6), 437-460, 2015 | 1057 | 2015 |
Ghrelin controls hippocampal spine synapse density and memory performance S Diano, SA Farr, SC Benoit, EC McNay, I da Silva, B Horvath, FS Gaskin, ... Nature neuroscience 9 (3), 381-388, 2006 | 1012 | 2006 |
Minireview: ghrelin and the regulation of energy balance—a hypothalamic perspective TL Horvath, S Diano, P Sotonyi, M Heiman, M Tschöp Endocrinology 142 (10), 4163-4169, 2001 | 815 | 2001 |
UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals ZB Andrews, ZW Liu, N Walllingford, DM Erion, E Borok, JM Friedman, ... Nature 454 (7206), 846-851, 2008 | 805 | 2008 |
ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury CD Toran-Allerand, X Guan, NJ MacLusky, TL Horvath, S Diano, M Singh, ... Journal of Neuroscience 22 (19), 8391-8401, 2002 | 715 | 2002 |
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system TL Horvath, C Peyron, S Diano, A Ivanov, G Aston‐Jones, TS Kilduff, ... Journal of Comparative Neurology 415 (2), 145-159, 1999 | 713 | 1999 |
Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations TL Horvath, S Diano, AN van den Pol Journal of Neuroscience 19 (3), 1072-1087, 1999 | 639 | 1999 |
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding GM Leinninger, YH Jo, RL Leshan, GW Louis, H Yang, JG Barrera, ... Cell metabolism 10 (2), 89-98, 2009 | 503 | 2009 |
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response R Winsky-Sommerer, A Yamanaka, S Diano, E Borok, AJ Roberts, ... Journal of Neuroscience 24 (50), 11439-11448, 2004 | 503 | 2004 |
Nicotine decreases food intake through activation of POMC neurons YS Mineur, A Abizaid, Y Rao, R Salas, RJ DiLeone, D Gündisch, S Diano, ... Science 332 (6035), 1330-1332, 2011 | 495 | 2011 |
Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals Q Gao, G Mezei, Y Nie, Y Rao, CS Choi, I Bechmann, C Leranth, ... Nature medicine 13 (1), 89-94, 2007 | 478 | 2007 |
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity TL Horvath, B Sarman, C García-Cáceres, PJ Enriori, P Sotonyi, ... Proceedings of the national academy of sciences 107 (33), 14875-14880, 2010 | 462 | 2010 |
Hypothalamic POMC neurons promote cannabinoid-induced feeding M Koch, L Varela, JG Kim, JD Kim, F Hernández-Nuño, SE Simonds, ... Nature 519 (7541), 45-50, 2015 | 456 | 2015 |
Mitochondrial uncoupling proteins in the CNS: in support of function and survival ZB Andrews, S Diano, TL Horvath Nature Reviews Neuroscience 6 (11), 829-840, 2005 | 445 | 2005 |
Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding JG Kim, S Suyama, M Koch, S Jin, P Argente-Arizon, J Argente, ZW Liu, ... Nature neuroscience 17 (7), 908-910, 2014 | 356 | 2014 |
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2 A Coppola, ZW Liu, ZB Andrews, E Paradis, MC Roy, JM Friedman, ... Cell metabolism 5 (1), 21-33, 2007 | 350 | 2007 |
Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity S Diano, ZW Liu, JK Jeong, MO Dietrich, HB Ruan, E Kim, S Suyama, ... Nature medicine 17 (9), 1121-1127, 2011 | 306 | 2011 |