| Structural basis for inhibition of the epidermal growth factor receptor by cetuximab S Li, KR Schmitz, PD Jeffrey, JJW Wiltzius, P Kussie, KM Ferguson Cancer cell 7 (4), 301-311, 2005 | 1337 | 2005 |
| Structural evaluation of EGFR inhibition mechanisms for nanobodies/VHH domains KR Schmitz, A Bagchi, RC Roovers, PMPB en Henegouwen, ... Structure 21 (7), 1214-1224, 2013 | 219 | 2013 |
| Golgi localization of glycosyltransferases requires a Vps74p oligomer KR Schmitz, J Liu, S Li, TG Setty, CS Wood, CG Burd, KM Ferguson Developmental cell 14 (4), 523-534, 2008 | 190 | 2008 |
| Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids K Moravcevic, JM Mendrola, KR Schmitz, YH Wang, D Slochower, ... Cell 143 (6), 966-977, 2010 | 187 | 2010 |
| PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking CS Wood, KR Schmitz, NJ Bessman, TG Setty, KM Ferguson, CG Burd Journal of Cell Biology 187 (7), 967-975, 2009 | 183 | 2009 |
| Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine JC Cordova, AO Olivares, Y Shin, BM Stinson, S Calmat, KR Schmitz, ... Cell 158 (3), 647-658, 2014 | 153 | 2014 |
| Interaction of antibodies with ErbB receptor extracellular regions KR Schmitz, KM Ferguson Experimental cell research 315 (4), 659-670, 2009 | 135 | 2009 |
| Nucleotide binding and conformational switching in the hexameric ring of a AAA+ machine BM Stinson, AR Nager, SE Glynn, KR Schmitz, TA Baker, RT Sauer Cell 153 (3), 628-639, 2013 | 126 | 2013 |
| Restriction of the conformational dynamics of the cyclic acyldepsipeptide antibiotics improves their antibacterial activity DW Carney, KR Schmitz, JV Truong, RT Sauer, JK Sello Journal of the American Chemical Society 136 (5), 1922-1929, 2014 | 114 | 2014 |
| Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery KR Schmitz, DW Carney, JK Sello, RT Sauer Proceedings of the National Academy of Sciences 111 (43), E4587-E4595, 2014 | 102 | 2014 |
| Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase CL Compton, KR Schmitz, RT Sauer, JK Sello ACS chemical biology 8 (12), 2669-2677, 2013 | 90 | 2013 |
| Substrate delivery by the AAA+ ClpX and ClpC1 unfoldases activates the mycobacterial ClpP1P2 peptidase KR Schmitz, RT Sauer Molecular microbiology 93 (4), 617-628, 2014 | 78 | 2014 |
| Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1 CC Lin, YS Huoh, KR Schmitz, LE Jensen, KM Ferguson Structure 16 (12), 1806-1816, 2008 | 59 | 2008 |
| Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpX BM Stinson, V Baytshtok, KR Schmitz, TA Baker, RT Sauer Nature structural & molecular biology 22 (5), 411-416, 2015 | 49 | 2015 |
| Comparison of Saccharomyces cerevisiae F-BAR domain structures reveals a conserved inositol phosphate binding site K Moravcevic, D Alvarado, KR Schmitz, JA Kenniston, JM Mendrola, ... Structure 23 (2), 352-363, 2015 | 46 | 2015 |
| A simple fragment of cyclic acyldepsipeptides is necessary and sufficient for ClpP activation and antibacterial activity DW Carney, CL Compton, KR Schmitz, JP Stevens, RT Sauer, JK Sello ChemBioChem 15 (15), 2216-2220, 2014 | 44 | 2014 |
| Highly dynamic interactions maintain kinetic stability of the ClpXP protease during the ATP-fueled mechanical cycle AJ Amor, KR Schmitz, JK Sello, TA Baker, RT Sauer ACS chemical biology 11 (6), 1552-1560, 2016 | 30 | 2016 |
| Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation AJ Amor, KR Schmitz, TA Baker, RT Sauer Protein Science 28 (4), 756-765, 2019 | 26 | 2019 |
| The role of the conserved COOH-terminal triad in alphaA-crystallin aggregation and functionality Y Li, KR Schmitz, JC Salerno, JF Koretz Mol Vis 13, 1758-1768, 2007 | 13 | 2007 |
| Acyldepsipeptide Antibiotics and a Bioactive Fragment Thereof Differentially Perturb Mycobacterium tuberculosis ClpXP1P2 Activity in Vitro KR Schmitz, EL Handy, CL Compton, S Gupta, WR Bishai, RT Sauer, ... ACS chemical biology 18 (4), 724-733, 2020 | 12 | 2020 |
Kathryn M. FergusonYale UniversityVerified email at yale.edu
