Adam L MacLean
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Defining epidermal basal cell states during skin homeostasis and wound healing using single-cell transcriptomics
D Haensel, S Jin, P Sun, R Cinco, M Dragan, Q Nguyen, Z Cang, Y Gong, ...
Cell reports 30 (11), 3932-3947. e6, 2020
Cell lineage and communication network inference via optimization for single-cell transcriptomics
S Wang, M Karikomi, AL MacLean, Q Nie
Nucleic acids research 47 (11), e66-e66, 2019
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
S Wang, ML Drummond, CF Guerrero-Juarez, E Tarapore, AL MacLean, ...
Nature communications 11 (1), 4239, 2020
Multiscale modeling of inflammation-induced tumorigenesis reveals competing oncogenic and oncoprotective roles for inflammation
Y Guo, Q Nie, AL MacLean, Y Li, J Lei, S Li
Cancer research 77 (22), 6429-6441, 2017
scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data
S Jin, AL MacLean, T Peng, Q Nie
Bioinformatics 34 (12), 2077-2086, 2018
Exploring intermediate cell states through the lens of single cells
AL MacLean, T Hong, Q Nie
Current Opinion in Systems Biology 9, 32-41, 2018
The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia
AL MacLean, S Filippi, MPH Stumpf
Proceedings of the National Academy of Sciences 111 (10), 3883-3888, 2014
Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis
B Lambert, AL MacLean, AG Fletcher, AN Combes, MH Little, HM Byrne
Journal of mathematical biology 76, 1673-1697, 2018
A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions
T Peng, L Liu, AL MacLean, CW Wong, W Zhao, Q Nie
BMC systems biology 11, 1-15, 2017
Parameter-free methods distinguish Wnt pathway models and guide design of experiments
AL MacLean, Z Rosen, HM Byrne, HA Harrington
Proceedings of the National Academy of Sciences 112 (9), 2652-2657, 2015
Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled
AL MacLean, C Lo Celso, MPH Stumpf
Journal of the Royal Society Interface 10 (81), 20120968, 2013
Concise review: stem cell population biology: insights from hematopoiesis
AL MacLean, C Lo Celso, MPH Stumpf
Stem Cells 35 (1), 80-88, 2017
Pathogenesis, symptomatology, and transmission of SARS-CoV-2 through analysis of viral genomics and structure
HM Rando, AL MacLean, AJ Lee, R Lordan, S Ray, V Bansal, AN Skelly, ...
MSystems 6 (5), 10.1128/msystems. 00095-21, 2021
An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
D Haensel, P Sun, AL MacLean, X Ma, Y Zhou, MP Stemmler, S Brabletz, ...
EMBO reports 20 (1), e46273, 2019
Julia for biologists
E Roesch, JG Greener, AL MacLean, H Nassar, C Rackauckas, TE Holy, ...
Nature methods 20 (5), 655-664, 2023
Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development
D Tatarakis, Z Cang, X Wu, PP Sharma, M Karikomi, AL MacLean, Q Nie, ...
Cell reports 37 (12), 2021
Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis
G Coulis, D Jaime, C Guerrero-Juarez, JM Kastenschmidt, PK Farahat, ...
Science advances 9 (27), eadd9984, 2023
Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points
ML Vainieri, AM Blagborough, AL MacLean, MLR Haltalli, N Ruivo, ...
Open biology 6 (6), 160038, 2016
Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia
HL Crowell, AL MacLean, MPH Stumpf
Journal of Theoretical Biology 401, 43-53, 2016
Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice
M Suo, MK Rommelfanger, Y Chen, EM Amro, B Han, Z Chen, ...
Blood, The Journal of the American Society of Hematology 139 (17), 2653-2665, 2022
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