| Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 J Huo, A Le Bas, RR Ruza, HME Duyvesteyn, H Mikolajek, T Malinauskas, ... Nature structural & molecular biology 27 (9), 846-854, 2020 | 477 | 2020 |
| Neutralization of SARS-CoV-2 by destruction of the prefusion spike J Huo, Y Zhao, J Ren, D Zhou, HME Duyvesteyn, HM Ginn, L Carrique, ... Cell host & microbe 28 (3), 445-454. e6, 2020 | 366 | 2020 |
| Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient D Zhou, HME Duyvesteyn, CP Chen, CG Huang, TH Chen, SR Shih, ... Nature structural & molecular biology 27 (10), 950-958, 2020 | 286 | 2020 |
| Structures of influenza A virus RNA polymerase offer insight into viral genome replication H Fan, AP Walker, L Carrique, JR Keown, I Serna Martin, D Karia, ... Nature 573 (7773), 287-290, 2019 | 160 | 2019 |
| Structural basis of homo-and heterotrimerization of collagen I U Sharma, L Carrique, S Vadon-Le Goff, N Mariano, RN Georges, ... Nature communications 8 (1), 14671, 2017 | 99 | 2017 |
| Host ANP32A mediates the assembly of the influenza virus replicase L Carrique, H Fan, AP Walker, JR Keown, J Sharps, E Staller, WS Barclay, ... Nature 587 (7835), 638-643, 2020 | 90 | 2020 |
| Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins M Renner, W Dejnirattisai, L Carrique, IS Martin, D Karia, SL Ilca, SF Ho, ... Nature Communications 12 (1), 1238, 2021 | 44 | 2021 |
| Parallel evolution in the emergence of highly pathogenic avian influenza A viruses M Escalera-Zamudio, M Golden, B Gutiérrez, J Thézé, JR Keown, ... Nature Communications 11 (1), 5511, 2020 | 35 | 2020 |
| Structure, mechanism, and inhibition of Hedgehog acyltransferase CE Coupland, SA Andrei, TB Ansell, L Carrique, P Kumar, L Sefer, ... Molecular cell 81 (24), 5025-5038. e10, 2021 | 31 | 2021 |
| The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer L Carrique, HME Duyvesteyn, T Malinauskas, Y Zhao, J Ren, D Zhou, ... BioRxiv, 2020.08. 13.249177, 2020 | 16 | 2020 |
| Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies JR Keown, Z Zhu, L Carrique, H Fan, AP Walker, I Serna Martin, E Pardon, ... Nature communications 13 (1), 251, 2022 | 14 | 2022 |
| Accelerating drug target inhibitor discovery with a deep generative foundation model V Chenthamarakshan, SC Hoffman, CD Owen, P Lukacik, ... Science Advances 9 (25), eadg7865, 2023 | 11 | 2023 |
| Exploring molecular determinants of polysaccharide lyase family 6–1 enzyme activity S Violot, F Galisson, L Carrique, V Jugnarain, L Conchou, X Robert, ... Glycobiology 31 (11), 1557-1570, 2021 | 11 | 2021 |
| Structural characterisation of a nanobody derived from a naïve library that neutralises SARS-CoV-2 J Huo, AL Bas, RR Ruza, HM Duyvesteyn, H Mikolajek, T Malinauskas, ... | 8 | 2020 |
| Influenza A virus RNA polymerase structures provide insights into viral genome replication H Fan, AP Walker, L Carrique, JR Keown, IS Martin, D Karia, J Sharps, ... Nature 573 (7773), 287, 2019 | 6 | 2019 |
| Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase L Carrique, L Ballut, A Shukla, N Varma, R Ravi, S Violot, B Srinivasan, ... Nature Communications 11 (1), 3228, 2020 | 5 | 2020 |
| LipIDens: simulation assisted interpretation of lipid densities in cryo-EM structures of membrane proteins TB Ansell, W Song, CE Coupland, L Carrique, RA Corey, AL Duncan, ... Nature Communications 14 (1), 7774, 2023 | 4 | 2023 |
| Structure and mechanism of hedgehog acyl transferase CE Coupland, SA Andrei, TB Ansell, L Carrique, P Kumar, L Sefer, ... BioRxiv, 2021.07. 08.451580, 2021 | 3 | 2021 |
| A high resolution view of an adolescent flavivirus M Renner, W Dejnirattisai, L Carrique, IS Martin, D Karia, SL Ilca, SF Ho, ... bioRxiv, 2020.06. 07.138669, 2020 | 3 | 2020 |
| Dimerisation of the influenza virus RNA polymerase during viral genome replication A Walker, H Fan, L Carrique, J Keown, D Bauer, J Grimes, E Fodor Access Microbiology 1 (1A), 292, 2019 | 2 | 2019 |
Jeremy R. KeownAssistant Professor, University of Warwick, UKVerified email at warwick.ac.uk
