A remarkable difference that one fluorine atom confers on the mechanisms of inactivation of human ornithine aminotransferase by two cyclohexene analogues of γ-aminobutyric acid W Zhu, PF Doubleday, DS Catlin, PM Weerawarna, A Butrin, S Shen, ... Journal of the American Chemical Society 142 (10), 4892-4903, 2020 | 23 | 2020 |
Remarkable and Unexpected Mechanism for (S)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine … W Zhu, PF Doubleday, A Butrin, PM Weerawarna, RD Melani, DS Catlin, ... Journal of the American Chemical Society 143 (21), 8193-8207, 2021 | 13 | 2021 |
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine … S Shen, A Butrin, PF Doubleday, RD Melani, BA Beaupre, MT Tavares, ... Journal of the American Chemical Society 143 (23), 8689-8703, 2021 | 9 | 2021 |
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation … W Zhu, A Butrin, RD Melani, PF Doubleday, GM Ferreira, MT Tavares, ... Journal of the American Chemical Society 144 (12), 5629-5642, 2022 | 7 | 2022 |
Perturbing the movement of hydrogens to delineate and assign events in the reductive activation and turnover of porcine dihydropyrimidine dehydrogenase BA Beaupre, DC Forouzesh, A Butrin, D Liu, GR Moran Biochemistry 60 (22), 1764-1775, 2021 | 7 | 2021 |
The interaction of porcine dihydropyrimidine dehydrogenase with the chemotherapy sensitizer: 5-ethynyluracil DC Forouzesh, BA Beaupre, A Butrin, Z Wawrzak, D Liu, GR Moran Biochemistry 60 (14), 1120-1132, 2021 | 7 | 2021 |
Structural and Kinetic Analyses Reveal the Dual Inhibition Modes of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1 … A Butrin, BA Beaupre, N Kadamandla, P Zhao, S Shen, RB Silverman, ... ACS chemical biology 16 (1), 67-75, 2020 | 7 | 2020 |
Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase A Butrin, A Butrin, Z Wawrzak, GR Moran, D Liu Journal of Biological Chemistry 298 (6), 2022 | 5 | 2022 |
The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mono‐and Biruthenium Polypyridyl Complexes with G‐Quadruplex DNA CG Mikek, VR Machha, JC White, LR Martin, SJ West, A Butrin, ... European Journal of Inorganic Chemistry 2017 (33), 3953-3960, 2017 | 4 | 2017 |
Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3S,4S)-3-Amino-4-fluorocyclopentenecarboxylic Acid S Shen, A Butrin, BA Beaupre, GM Ferreira, PF Doubleday, DH Grass, ... Molecules 28 (3), 1133, 2023 | 1 | 2023 |
Correction to “Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second … W Zhu, A Butrin, RD Melani, PF Doubleday, GM Ferreira, MT Tavares, ... Journal of the American Chemical Society 145 (17), 9895-9896, 2023 | | 2023 |
Structural and Transient Kinetic Analysis on Mechanism-Based Inactivators of Human Ornithine Aminotransferase A Butrin Loyola University Chicago, 2022 | | 2022 |
Rational Design, Synthesis, and Mechanism of (3S, 4R)-3-Amino-4-(difluoromethyl) cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of … W Zhu, A Butrin, RD Melani, PF Doubleday, GM Ferreira, MT Tavares, ... | | |