| The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity LK Shewell, RM Harvey, MA Higgins, CJ Day, LE Hartley-Tassell, ... Proceedings of the National Academy of Sciences 111 (49), E5312-E5320, 2014 | 139 | 2014 |
| A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate YL Du, HY He, MA Higgins, KS Ryan Nature Chemical Biology 13 (8), 836-838, 2017 | 108 | 2017 |
| Identification and structural basis of binding to host lung glycogen by streptococcal virulence factors AL Van Bueren, M Higgins, D Wang, RD Burke, AB Boraston Nature structural & molecular biology 14 (1), 76-84, 2007 | 100 | 2007 |
| The molecular basis of glycogen breakdown and transport in Streptococcus pneumoniae DW Abbott, MA Higgins, S Hyrnuik, B Pluvinage, A Lammerts van Bueren, ... Molecular microbiology 77 (1), 183-199, 2010 | 83 | 2010 |
| Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus pneumoniae β-galactosidase, BgaA AK Singh, B Pluvinage, MA Higgins, AB Dalia, SA Woodiga, M Flynn, ... PLoS pathogens 10 (9), e1004364, 2014 | 69 | 2014 |
| Toward efficient enzymes for the generation of universal blood through structure-guided directed evolution DH Kwan, I Constantinescu, R Chapanian, MA Higgins, MP Kötzler, ... Journal of the American Chemical Society 137 (17), 5695-5705, 2015 | 58 | 2015 |
| The conformation and function of a multimodular glycogen-degrading pneumococcal virulence factor AL van Bueren, E Ficko-Blean, B Pluvinage, JH Hehemann, MA Higgins, ... Structure 19 (5), 640-651, 2011 | 57 | 2011 |
| Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis B Pluvinage, MA Higgins, DW Abbott, C Robb, AB Dalia, L Deng, ... Structure 19 (11), 1603-1614, 2011 | 52 | 2011 |
| Differential recognition and hydrolysis of host carbohydrate antigens by Streptococcus pneumoniae family 98 glycoside hydrolases MA Higgins, GE Whitworth, N El Warry, M Randriantsoa, E Samain, ... Journal of Biological Chemistry 284 (38), 26161-26173, 2009 | 50 | 2009 |
| A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival J Batra, CM Nagle, T O'Mara, M Higgins, Y Dong, OL Tan, F Lose, ... BMC cancer 11, 1-11, 2011 | 33 | 2011 |
| Blood group antigen recognition by a solute-binding protein from a serotype 3 strain of Streptococcus pneumoniae MA Higgins, DW Abbott, MJ Boulanger, AB Boraston Journal of molecular biology 388 (2), 299-309, 2009 | 31 | 2009 |
| The overall architecture and receptor binding of pneumococcal carbohydrate-antigen-hydrolyzing enzymes MA Higgins, E Ficko-Blean, PJ Meloncelli, TL Lowary, AB Boraston Journal of molecular biology 411 (5), 1017-1036, 2011 | 27 | 2011 |
| A second β-hexosaminidase encoded in the Streptococcus pneumoniae genome provides an expanded biochemical ability to degrade host glycans M Robb, CS Robb, MA Higgins, JK Hobbs, JC Paton, AB Boraston Journal of Biological Chemistry 290 (52), 30888-30900, 2015 | 24 | 2015 |
| Structural and functional analysis of fucose-processing enzymes from Streptococcus pneumoniae MA Higgins, MD Suits, C Marsters, AB Boraston Journal of molecular biology 426 (7), 1469-1482, 2014 | 23 | 2014 |
| Structure aided design of a Neu5Gc specific lectin CJ Day, AW Paton, MA Higgins, LK Shewell, FEC Jen, BL Schulz, ... Scientific reports 7 (1), 1495, 2017 | 18 | 2017 |
| Comparative Genomics Identified a Genetic Locus in Plant-Associated Pseudomonas spp. That Is Necessary for Induced Systemic Susceptibility P Beskrovnaya, RA Melnyk, Z Liu, Y Liu, MA Higgins, Y Song, KS Ryan, ... MBio 11 (3), 10.1128/mbio. 00575-20, 2020 | 16 | 2020 |
| Convergent biosynthetic transformations to a bacterial specialized metabolite YL Du, MA Higgins, G Zhao, KS Ryan Nature Chemical Biology 15 (11), 1043-1048, 2019 | 10 | 2019 |
| Structural characterization of the PTS IIA and IIB proteins associated with pneumococcal fucose utilization MA Higgins, AM Hamilton, AB Boraston Proteins: Structure, Function, and Bioinformatics 85 (5), 963-968, 2017 | 7 | 2017 |
| The pneumococcal alpha-glycerophosphate oxidase enhances nasopharyngeal colonization through binding to host glycoconjugates LK Mahdi, MA Higgins, CJ Day, J Tiralongo, LE Hartley-Tassell, ... EBioMedicine 18, 236-243, 2017 | 7 | 2017 |
| Structure of the fucose mutarotase from Streptococcus pneumoniae in complex with l-fucose MA Higgins, AB Boraston Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 7 | 2011 |
