Jeffrey Horowitz
Jeffrey Horowitz
The Ohio State University Wexner Medical Center
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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
L Hecker, R Vittal, T Jones, R Jagirdar, TR Luckhardt, JC Horowitz, ...
Nature medicine 15 (9), 1077-1081, 2009
Myofibroblast differentiation by transforming growth factor-ॆ1 Is dependent on cell adhesion and integrin signaling via focal adhesion kinase
VJ Thannickal, DY Lee, ES White, Z Cui, JM Larios, R Chacon, ...
Journal of Biological Chemistry 278 (14), 12384-12389, 2003
Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation
AJ Booth, R Hadley, AM Cornett, AA Dreffs, SA Matthes, JL Tsui, K Weiss, ...
American journal of respiratory and critical care medicine 186 (9), 866-876, 2012
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
F Liu, D Lagares, KM Choi, L Stopfer, A Marinković, V Vrbanac, CK Probst, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (4 …, 2015
Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
VJ Thannickal, JC Horowitz
Proceedings of the American Thoracic Society 3 (4), 350-356, 2006
Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
M Waghray, Z Cui, JC Horowitz, IM Subramanian, FJ Martinez, GB Toews, ...
The FASEB journal 19 (7), 1-16, 2005
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-β1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an …
JC Horowitz, DY Lee, M Waghray, VG Keshamouni, PE Thomas, H Zhang, ...
Journal of Biological Chemistry 279 (2), 1359-1367, 2004
Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts
JC Horowitz, DS Rogers, V Sharma, R Vittal, ES White, Z Cui, ...
Cellular signalling 19 (4), 761-771, 2007
What's in a name? That which we call IPF, by any other name would act the same
AU Wells, KK Brown, KR Flaherty, M Kolb, VJ Thannickal
European Respiratory Journal 51 (5), 2018
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report
TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, ...
American journal of respiratory and critical care medicine 189 (2), 214-222, 2014
Endothelin-1 and transforming growth factor-β1 independently induce fibroblast resistance to apoptosis via AKT activation
P Kulasekaran, CA Scavone, DS Rogers, DA Arenberg, VJ Thannickal, ...
American journal of respiratory cell and molecular biology 41 (4), 484-493, 2009
Prostaglandin E2 induces fibroblast apoptosis by modulating multiple survival pathways
SK Huang, ES White, SH Wettlaufer, H Grifka, CM Hogaboam, ...
The FASEB Journal 23 (12), 4317-4326, 2009
Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury
R Vittal, JC Horowitz, BB Moore, H Zhang, FJ Martinez, GB Toews, ...
The American journal of pathology 166 (2), 367-375, 2005
Extracellular matrix in lung development, homeostasis and disease
Y Zhou, JC Horowitz, A Naba, N Ambalavanan, K Atabai, J Balestrini, ...
Matrix Biology 73, 77-104, 2018
Epithelial-mesenchymal interactions in pulmonary fibrosis
JC Horowitz, VJ Thannickal
Seminars in respiratory and critical care medicine 27 (06), 600-612, 2006
Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts
LA Johnson, ES Rodansky, KL Sauder, JC Horowitz, JD Mih, ...
Inflammatory bowel diseases 19 (5), 891-903, 2013
Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis
TH Sisson, IO Ajayi, N Subbotina, AE Dodi, ES Rodansky, LN Chibucos, ...
The American journal of pathology 185 (4), 969-986, 2015
Plasminogen activation–induced pericellular fibronectin proteolysis promotes fibroblast apoptosis
JC Horowitz, DS Rogers, RH Simon, TH Sisson, VJ Thannickal
American journal of respiratory cell and molecular biology 38 (1), 78-87, 2008
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts
SK Huang, AM Scruggs, J Donaghy, JC Horowitz, Z Zaslona, ...
Cell death & disease 4 (5), e621-e621, 2013
Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute
VJ Thannickal, CA Henke, JC Horowitz, PW Noble, J Roman, PJ Sime, ...
The American journal of pathology 184 (6), 1643-1651, 2014
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