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Graeme Cowan
Graeme Cowan
Institute of Immunology and Infection Research, University of Edinburgh
Verified email at ed.ac.uk - Homepage
Title
Cited by
Cited by
Year
Presence of Nonhemolytic Pneumolysin in Serotypes of Streptococcus pneumoniae Associated with Disease Outbreaks
JMC Jefferies, CHG Johnston, LAS Kirkham, GJM Cowan, KS Ross, ...
Journal of Infectious Diseases 196 (6), 936-944, 2007
1122007
α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized …
L Stevenson, E Laursen, GJ Cowan, B Bandoh, L Barfod, DR Cavanagh, ...
PLoS pathogens 11 (7), e1005022, 2015
902015
The human‐specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein
H Nagamune, K Ohkura, A Sukeno, G Cowan, TJ Mitchell, W Ito, ...
Microbiology and immunology 48 (9), 677-692, 2004
582004
The mechanism of pneumolysin‐induced cochlear hair cell death in the rat
M Beurg, A Hafidi, L Skinner, G Cowan, Y Hondarrague, TJ Mitchell, ...
The Journal of physiology 568 (1), 211-227, 2005
502005
Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria
N Imai, N Rujeni, N Nausch, CD Bourke, LJ Appleby, G Cowan, R Gwisai, ...
Parasitology 138 (12), 1519-1533, 2011
472011
Novel mucosal vaccines generated by genetic conjugation of heterologous proteins to pneumolysin (PLY) from Streptococcus pneumoniae
G Douce, K Ross, G Cowan, J Ma, TJ Mitchell
Vaccine 28 (18), 3231-3237, 2010
432010
Pneumolysin‐mediated activation of NFκB in human neutrophils is antagonized by docosahexaenoic acid
H Fickl, R Cockeran, HC Steel, C Feldman, G Cowan, TJ Mitchell, ...
Clinical & Experimental Immunology 140 (2), 274-281, 2005
422005
A malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune response
GJM Cowan, AM Creasey, K Dhanasarnsombut, AW Thomas, ...
PLoS One 6 (10), e26616, 2011
362011
immune Tolerance to apoptotic self is Mediated Primarily by regulatory B1a cells
K Miles, J Simpson, S Brown, G Cowan, D Gray, M Gray
Frontiers in immunology 8, 1952, 2018
342018
Loss of the protein tyrosine phosphatase PTPN22 reduces mannan-induced autoimmune arthritis in SKG mice
S Sood, RJ Brownlie, C Garcia, G Cowan, RJ Salmond, S Sakaguchi, ...
The Journal of Immunology 197 (2), 429-440, 2016
262016
Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59
TR Hughes, KS Ross, GJM Cowan, B Sivasankar, CL Harris, TJ Mitchell, ...
Molecular immunology 46 (7), 1561-1567, 2009
262009
Immunisation with anthrolysin O or a genetic toxoid protects against challenge with the toxin but not against Bacillus anthracis
GJM Cowan, HS Atkins, LK Johnson, RW Titball, TJ Mitchell
Vaccine 25 (41), 7197-7205, 2007
252007
A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila
GJM Cowan, U Bockau, J Eleni-Muus, I Aldag, K Samuel, AM Creasey, ...
PloS one 9 (1), e87198, 2014
232014
Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma
G Cowan, NJ Weston-Bell, D Bryant, A Seckinger, D Hose, N Zojer, ...
Oncotarget 6 (15), 13229, 2015
222015
Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery–Dreifuss muscular dystrophy
P Meinke, P Schneiderat, V Srsen, N Korfali, P Lê Thành, GJM Cowan, ...
Neuromuscular Disorders 25 (2), 127-136, 2015
222015
In human autoimmunity, a substantial component of the B cell repertoire consists of polyclonal, barely mutated IgG+ ve B cells
GJM Cowan, K Miles, L Capitani, SSB Giguere, H Johnsson, ...
Frontiers in Immunology 11, 395, 2020
212020
Antibody responses to a novel Plasmodium falciparum merozoite surface protein vaccine correlate with protection against experimental malaria infection in Aotus monkeys
DR Cavanagh, CHM Kocken, JH White, GJM Cowan, K Samuel, ...
PLoS One 9 (1), e83704, 2014
192014
Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni
M Higon, G Cowan, N Nausch, D Cavanagh, A Oleaga, R Toledo, ...
Parasitology 138 (12), 1607-1619, 2011
172011
Immunological consequences of antihelminthic treatment in preschool children exposed to urogenital schistosome infection
N Rujeni, N Nausch, N Midzi, GJ Cowan, R Burchmore, DR Cavanagh, ...
Journal of tropical medicine 2013, 2013
132013
A Conserved TCRβ signature dominates a highly polyclonal T-cell expansion during the acute phase of a murine malaria infection
NL Smith, W Nahrendorf, C Sutherland, JP Mooney, J Thompson, ...
Frontiers in immunology 11, 587756, 2020
112020
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