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Harry Gristick
Harry Gristick
Verified email at caltech.edu
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Year
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
CO Barnes, CA Jette, ME Abernathy, KMA Dam, SR Esswein, HB Gristick, ...
Nature 588 (7839), 682-687, 2020
13762020
Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
CO Barnes, AP West, KE Huey-Tubman, MAG Hoffmann, NG Sharaf, ...
Cell 182 (4), 828-842. e16, 2020
7552020
Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico
DF Robbiani, L Bozzacco, JR Keeffe, R Khouri, PC Olsen, A Gazumyan, ...
Cell 169 (4), 597-609. e11, 2017
3422017
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
HB Gristick, L von Boehmer, AP West Jr, M Schamber, A Gazumyan, ...
Nature structural & molecular biology 23 (10), 906-915, 2016
2022016
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ...
Science translational medicine 9 (373), eaal2144, 2017
1662017
Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop
H Wang, AA Cohen, RP Galimidi, HB Gristick, GJ Jensen, PJ Bjorkman
Proceedings of the National Academy of Sciences 113 (46), E7151-E7158, 2016
1582016
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
A Escolano, HB Gristick, ME Abernathy, J Merkenschlager, R Gautam, ...
Nature 570 (7762), 468-473, 2019
1412019
Restriction of HIV-1 escape by a highly broad and potent neutralizing antibody
P Schommers, H Gruell, ME Abernathy, MK Tran, AS Dingens, HB Gristick, ...
Cell 180 (3), 471-489. e22, 2020
1022020
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope
CO Barnes, HB Gristick, NT Freund, A Escolano, AY Lyubimov, ...
Nature communications 9 (1), 1251, 2018
982018
An ACE2 microbody containing a single immunoglobulin Fc domain is a potent inhibitor of SARS-CoV-2
T Tada, C Fan, JS Chen, R Kaur, KA Stapleford, H Gristick, BM Dcosta, ...
Cell Reports 33 (12), 2020
742020
Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4
HB Gristick, M Rao, JW Chartron, ME Rome, S Shan, WM Clemons Jr
nAture structurAl & moleculAr biology 21 (5), 437-442, 2014
632014
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies
H Wang, HB Gristick, L Scharf, AP West Jr, RP Galimidi, MS Seaman, ...
Elife 6, e27389, 2017
592017
Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway
ME Rome, US Chio, M Rao, H Gristick, S Shan
Proceedings of the National Academy of Sciences 111 (46), E4929-E4935, 2014
472014
Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody
Z Yang, H Wang, AZ Liu, HB Gristick, PJ Bjorkman
Nature structural & molecular biology 26 (12), 1167-1175, 2019
432019
Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies
CO Barnes, CA Jette, ME Abernathy, KMA Dam, SR Esswein, HB Gristick, ...
bioRxiv, 2020
362020
Crystal structure of mitochondrial fission complex reveals scaffolding function for mitochondrial division 1 (Mdv1) coiled coil
Y Zhang, NC Chan, HB Ngo, H Gristick, DC Chan
Journal of Biological Chemistry 287 (13), 9855-9861, 2012
312012
Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells
MAG Hoffmann, Y Bar-On, Z Yang, HB Gristick, PNP Gnanapragasam, ...
Proceedings of the National Academy of Sciences 117 (31), 18719-18728, 2020
262020
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
A Escolano, HB Gristick, R Gautam, AT DeLaitsch, ME Abernathy, Z Yang, ...
Science translational medicine 13 (621), eabk1533, 2021
242021
Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer
Z Yang, KMA Dam, MD Bridges, MAG Hoffmann, AT DeLaitsch, ...
Nature communications 13 (1), 732, 2022
192022
X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer
HB Gristick, H Wang, PJ Bjorkman
Acta Crystallographica Section D: Structural Biology 73 (10), 822-828, 2017
182017
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