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Dongfen Yuan
Dongfen Yuan
Janssen
Verified email at its.jnj.com
Title
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Cited by
Year
Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations
MS Kim, MJ Haney, Y Zhao, D Yuan, I Deygen, NL Klyachko, AV Kabanov, ...
Nanomedicine: Nanotechnology, Biology and Medicine 14 (1), 195-204, 2018
6162018
Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain
D Yuan, Y Zhao, WA Banks, KM Bullock, M Haney, E Batrakova, ...
Biomaterials 142, 1-12, 2017
5252017
Physiologically based pharmacokinetic modeling of nanoparticles
D Yuan, H He, Y Wu, J Fan, Y Cao
Journal of pharmaceutical sciences 108 (1), 58-72, 2019
1462019
Pharmacokinetics and pharmacodynamics modeling and simulation systems to support the development and regulation of liposomal drugs
H He, D Yuan, Y Wu, Y Cao
Pharmaceutics 11 (3), 110, 2019
742019
Effect of octreotide–polyethylene glycol (100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with …
Z Su, J Niu, Y Xiao, Q Ping, M Sun, A Huang, W You, X Sang, D Yuan
Molecular pharmaceutics 8 (5), 1641-1651, 2011
702011
A novel lipoprotein-mimic nanocarrier composed of the modified protein and lipid for tumor cell targeting delivery
Y Xu, X Jin, Q Ping, J Cheng, M Sun, F Cao, W You, D Yuan
Journal of controlled release 146 (3), 299-308, 2010
572010
Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity
X Yi, D Yuan, SA Farr, WA Banks, CD Poon, AV Kabanov
Journal of Controlled Release 191, 34-46, 2014
502014
Intranasal delivery of N-terminal modified leptin-pluronic conjugate for treatment of obesity
D Yuan, X Yi, Y Zhao, CD Poon, KM Bullock, KM Hansen, TS Salameh, ...
Journal of Controlled Release 263, 172-184, 2017
292017
Effect of ligand density and PEG modification on octreotide-targeted liposome via somatostatin receptor in vitro and in vivo
H Li, D Yuan, M Sun, Q Ping
Drug Delivery 23 (9), 3562-3572, 2016
232016
Luteinizing hormone releasing hormone-targeted cisplatin-loaded magnetite nanoclusters for simultaneous MR imaging and chemotherapy of ovarian cancer
HM Vishwasrao, AM Master, YG Seo, XM Liu, N Pothayee, Z Zhou, ...
Chemistry of Materials 28 (9), 3024-3040, 2016
212016
A minimal physiologically based pharmacokinetic model with a nested endosome compartment for novel engineered antibodies
D Yuan, F Rode, Y Cao
The AAPS journal 20, 1-11, 2018
172018
Downregulation of Interferon-γ Receptor Expression Endows Resistance to Anti–Programmed Death Protein 1 Therapy in Colorectal Cancer
C Lv, D Yuan, Y Cao
Journal of Pharmacology and Experimental Therapeutics 376 (1), 21-28, 2021
92021
A systems pharmacokinetic/pharmacodynamic model for concizumab to explore the potential of anti-TFPI recycling antibodies
D Yuan, F Rode, Y Cao
European Journal of Pharmaceutical Sciences 138, 105032, 2019
42019
奥曲肽靶向阿霉素脂质体的制备及其体外性质
袁东芬, 孙敏捷, 王宇, 平其能
中国药科大学学报 42 (003), 223-229, 2011
42011
Efficacy, safety, pharmacokinetic (PK), and pharmacodynamic (PD) support for talquetamab (tal) QW and Q2W dosing in patients (pts) with relapsed/refractory multiple myeloma …
X Ma, J Gong, J Zhou, D Yuan, D Vishwamitra, B Hilder, TJ Masterson, ...
Journal of Clinical Oncology 41 (16_suppl), 8041-8041, 2023
32023
Biological agent-exosome compositions and uses thereof
EV Batrakova, AV Kabanov, M Sokolsky, MJ Haney, D Yuan, MS Kim
US Patent 11,458,097, 2022
12022
Biological agent-exosome compositions and uses thereof
EV Batrakova, AV Kabanov, M Sokolsky, MJ Haney, D Yuan, MS Kim
US Patent App. 17/821,576, 2022
2022
A Mechanistic Small Systems Model to Explore the Pharmacokinetics and Pharmacodynamics of Concizumab
D Yuan, F Rode, Y Cao
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S23-S23, 2018
2018
Delivery of Therapeutic Proteins to the Brain
D Yuan
The University of North Carolina at Chapel Hill, 2017
2017
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