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Federico Iovino
Federico Iovino
Associate Professor and Principal Investigator - Karolinska Institutet - Department of Neuroscience
Verified email at ki.se - Homepage
Title
Cited by
Cited by
Year
Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis
F Iovino, CJ Orihuela, HE Moorlag, G Molema, JJE Bijlsma
PloS one 8 (7), e68408, 2013
1082013
pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion
F Iovino, JY Engelen-Lee, M Brouwer, D van de Beek, A van der Ende, ...
Journal of Experimental Medicine 214 (6), 1619-1630, 2017
972017
Immunomodulatory effects of pneumococcal extracellular vesicles on cellular and humoral host defenses
M Codemo, S Muschiol, F Iovino, P Nannapaneni, L Plant, SN Wai, ...
MBio 9 (2), 10.1128/mbio. 00559-18, 2018
812018
How does Streptococcus pneumoniae invade the brain?
F Iovino, J Seinen, B Henriques-Normark, JM van Dijl
Trends in microbiology 24 (4), 307-315, 2016
802016
Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA
F Iovino, DL Hammarlöf, G Garriss, S Brovall, P Nannapaneni, ...
The Journal of clinical investigation 126 (8), 2821-2826, 2016
512016
Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier
F Iovino, G Molema, JJE Bijlsma
Infection and immunity 82 (9), 3555-3566, 2014
512014
Signalling or binding: The role of the platelet‐activating factor receptor in invasive pneumococcal disease
F Iovino, MC Brouwer, D van de Beek, G Molema, JJE Bijlsma
Cellular microbiology 15 (6), 870-881, 2013
512013
Streptococcus pneumoniae Invades Endothelial Host Cells via Multiple Pathways and Is Killed in a Lysosome Dependent Manner
H Gradstedt, F Iovino, JJE Bijlsma
PloS one 8 (6), e65626, 2013
492013
Streptococcus pneumoniae Interacts with pIgR Expressed by the Brain Microvascular Endothelium but Does Not Co-Localize with PAF Receptor
F Iovino, G Molema, JJE Bijlsma
PLoS One 9 (5), e97914, 2014
442014
Neuronal damage and neuroinflammation, a bridge between bacterial meningitis and neurodegenerative diseases
K Farmen, M Tofiño-Vian, F Iovino
Frontiers in Cellular Neuroscience 15, 680858, 2021
322021
The role of microglia in bacterial meningitis: inflammatory response, experimental models and new neuroprotective therapeutic strategies
S Thorsdottir, B Henriques-Normark, F Iovino
Frontiers in microbiology 10, 442622, 2019
312019
Luminescent CeO2: Eu3+ nanocrystals for robust in situ H2O2 real-time detection in bacterial cell cultures
DF Henning, P Merkl, C Yun, F Iovino, L Xie, E Mouzourakis, C Moularas, ...
Biosensors and Bioelectronics 132, 286-293, 2019
262019
Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease
K Subramanian, F Iovino, V Tsikourkitoudi, P Merkl, S Ahmed, SB Berry, ...
EMBO molecular medicine 12 (11), e12695, 2020
232020
Receptor blockade: a novel approach to protect the brain from pneumococcal invasion
F Iovino, S Thorsdottir, B Henriques-Normark
The Journal of infectious diseases 218 (3), 476-484, 2018
222018
Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin
M Tabusi, S Thorsdottir, M Lysandrou, AR Narciso, M Minoia, ...
PLoS pathogens 17 (3), e1009432, 2021
212021
The proteasome-ubiquitin system is required for efficient killing of intracellular Streptococcus pneumoniae by brain endothelial cells
F Iovino, H Gradstedt, JJ Bijlsma
MBio 5 (4), 10.1128/mbio. 00984-14, 2014
152014
The impact of the ancillary pilus‐1 protein RrgA of Streptococcus pneumoniae on colonization and disease
F Iovino, P Nannapaneni, B Henriques‐Normark, S Normark
Molecular microbiology 113 (3), 650-658, 2020
142020
Immunomodulatory effects of pneumococcal extracellular vesicles on cellular and humoral host defenses. mBio 9: e00559-18
M Codemo, S Muschiol, F Iovino, P Nannapaneni, L Plant, SN Wai, ...
132018
Bacterial meningitis in Africa
T Barichello, CH Rocha Catalão, UK Rohlwink, M Kuip, D Zaharie, ...
Frontiers in neurology 14, 822575, 2023
92023
Dysfunctional glymphatic system with disrupted aquaporin 4 expression pattern on astrocytes causes bacterial product accumulation in the CSF during Pneumococcal meningitis
JS Generoso, S Thorsdottir, A Collodel, D Dominguini, RRE Santo, ...
MBio 13 (5), e01886-22, 2022
92022
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