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Thomas Schmidt
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Long Distance Measurements up to 160 Å in the GroEL Tetradecamer Using Q‐Band DEER EPR Spectroscopy
T Schmidt, MA Wälti, JL Baber, EJ Hustedt, GM Clore
Angewandte Chemie International Edition 55 (51), 15905-15909, 2016
1852016
Basic amino-acid side chains regulate transmembrane integrin signalling
C Kim, T Schmidt, EG Cho, F Ye, TS Ulmer, MH Ginsberg
Nature 481 (7380), 209-213, 2012
1362012
Mutation in CPT1C associated with pure autosomal dominant spastic paraplegia
C Rinaldi, T Schmidt, AJ Situ, JO Johnson, PR Lee, K Chen, LC Bott, ...
JAMA neurology 72 (5), 561-570, 2015
832015
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression
M Zou, A Bhatia, H Dong, P Jayaprakash, J Guo, D Sahu, Y Hou, F Tsen, ...
Oncogene 36 (15), 2160-2171, 2017
762017
Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells
JM Kim, K Kim, T Schmidt, V Punj, H Tucker, JC Rice, TS Ulmer, W An
Nucleic acids research 43 (18), 8868-8883, 2015
742015
Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR
SA Kotler, V Tugarinov, T Schmidt, A Ceccon, DS Libich, R Ghirlando, ...
Proceedings of the National Academy of Sciences 116 (9), 3562-3571, 2019
692019
The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract
JM Bravo-Arredondo, NC Kegulian, T Schmidt, NK Pandey, AJ Situ, ...
Journal of Biological Chemistry 293 (51), 19613-19623, 2018
442018
Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection
AW Woodham, JR Taylor, AI Jimenez, JG Skeate, T Schmidt, HE Brand, ...
Journal of Antimicrobial Chemotherapy 70 (6), 1686-1690, 2015
432015
Interaction of huntingtin exon-1 peptides with lipid-based micellar nanoparticles probed by solution NMR and Q-band pulsed EPR
A Ceccon, T Schmidt, V Tugarinov, SA Kotler, CD Schwieters, GM Clore
Journal of the American Chemical Society 140 (20), 6199-6202, 2018
402018
Structural and thermodynamic basis of proline-induced transmembrane complex stabilization
T Schmidt, AJ Situ, TS Ulmer
Scientific reports 6 (1), 29809, 2016
352016
Characterization of membrane protein interactions by isothermal titration calorimetry
AJ Situ, T Schmidt, P Mazumder, TS Ulmer
Journal of molecular biology 426 (21), 3670-3680, 2014
342014
Time-resolved DEER EPR and solid-state NMR afford kinetic and structural elucidation of substrate binding to Ca2+-ligated calmodulin
T Schmidt, J Jeon, WM Yau, CD Schwieters, R Tycko, GM Clore
Proceedings of the National Academy of Sciences 119 (6), e2122308119, 2022
292022
Chaperonin GroEL accelerates protofibril formation and decorates fibrils of the Het-s prion protein
MA Wälti, T Schmidt, DT Murray, H Wang, JE Hinshaw, GM Clore
Proceedings of the National Academy of Sciences 114 (34), 9104-9109, 2017
282017
Quantitative Resolution of Monomer‐Dimer Populations by Inversion Modulated DEER EPR Spectroscopy
T Schmidt, R Ghirlando, J Baber, GM Clore
ChemPhysChem 17 (19), 2987-2991, 2016
272016
Submillisecond Freezing Permits Cryoprotectant-Free EPR Double Electron Electron Resonance Spectroscopy
T Schmidt, J Jeon, Y Okuno, SC Chiliveri, GM Clore
ChemPhysChem, 2020
252020
Annular anionic lipids stabilize the integrin αIIbβ3 transmembrane complex
T Schmidt, JE Suk, F Ye, AJ Situ, P Mazumder, MH Ginsberg, TS Ulmer
Journal of Biological Chemistry 290 (13), 8283-8293, 2015
252015
Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR
T Schmidt, CD Schwieters, GM Clore
Proceedings of the National Academy of Sciences 116 (36), 17809-17816, 2019
242019
A conserved ectodomain-transmembrane domain linker motif tunes the allosteric regulation of cell surface receptors
T Schmidt, F Ye, AJ Situ, W An, MH Ginsberg, TS Ulmer
Journal of Biological Chemistry 291 (34), 17536-17546, 2016
212016
Probing Conformational States of the Finger and Thumb Subdomains of HIV-1 Reverse Transcriptase Using Double Electron–Electron Resonance Electron Paramagnetic Resonance …
T Schmidt, L Tian, GM Clore
Biochemistry 57 (5), 489-493, 2018
142018
Direct evaluation of protein–lipid contacts reveals protein membrane immersion and isotropic bicelle structure
T Schmidt, AJ Situ, TS Ulmer
The Journal of Physical Chemistry Letters 7 (21), 4420-4426, 2016
122016
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