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Christopher H. Switzer
Christopher H. Switzer
Department of Molecular and Cell Biology, University of Leicester
Verified email at leicester.ac.uk
Title
Cited by
Cited by
Year
The chemical biology of nitric oxide: implications in cellular signaling
DD Thomas, LA Ridnour, JS Isenberg, W Flores-Santana, CH Switzer, ...
Free Radical Biology and Medicine 45 (1), 18-31, 2008
11002008
Nitric oxide and redox mechanisms in the immune response
DA Wink, HB Hines, RYS Cheng, CH Switzer, W Flores‐Santana, ...
Journal of leukocyte biology 89 (6), 873-891, 2011
8512011
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry
MD Bartberger, W Liu, E Ford, KM Miranda, C Switzer, JM Fukuto, ...
Proceedings of the National Academy of Sciences 99 (17), 10958-10963, 2002
4122002
Biological nitric oxide signalling: chemistry and terminology
TA Heinrich, RS Da Silva, KM Miranda, CH Switzer, DA Wink, JM Fukuto
British journal of pharmacology 169 (7), 1417-1429, 2013
2872013
Increased NOS2 predicts poor survival in estrogen receptor–negative breast cancer patients
SA Glynn, BJ Boersma, TH Dorsey, M Yi, HG Yfantis, LA Ridnour, ...
The Journal of clinical investigation 120 (11), 3843-3854, 2010
2602010
Molecular mechanisms for discrete nitric oxide levels in cancer
LA Ridnour, DD Thomas, C Switzer, W Flores-Santana, JS Isenberg, ...
Nitric oxide 19 (2), 73-76, 2008
2192008
Targeting SET/I2PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy
CH Switzer, RYS Cheng, TM Vitek, DJ Christensen, DA Wink, MP Vitek
Oncogene 30 (22), 2504-2513, 2011
1992011
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression
JL Heinecke, LA Ridnour, RYS Cheng, CH Switzer, MM Lizardo, ...
Proceedings of the National Academy of Sciences 111 (17), 6323-6328, 2014
1922014
Molecular pathways: toll-like receptors in the tumor microenvironment—poor prognosis or new therapeutic opportunity
LA Ridnour, RYS Cheng, CH Switzer, JL Heinecke, S Ambs, S Glynn, ...
Clinical Cancer Research 19 (6), 1340-1346, 2013
1692013
Nitroxyl (HNO): chemistry, biochemistry, and pharmacology
JM Fukuto, CH Switzer, KM Miranda, DA Wink
Annu. Rev. Pharmacol. Toxicol. 45, 335-355, 2005
1652005
Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake
JS Isenberg, Y Jia, J Fukuyama, CH Switzer, DA Wink, DD Roberts
Journal of Biological Chemistry 282 (21), 15404-15415, 2007
1512007
The emergence of nitroxyl (HNO) as a pharmacological agent
CH Switzer, W Flores-Santana, D Mancardi, S Donzelli, D Basudhar, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (7), 835-840, 2009
1392009
S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer
CH Switzer, SA Glynn, RYS Cheng, LA Ridnour, JE Green, S Ambs, ...
Molecular Cancer Research 10 (9), 1203-1215, 2012
1382012
Signaling and stress: The redox landscape in NOS2 biology
DD Thomas, JL Heinecke, LA Ridnour, RY Cheng, AH Kesarwala, ...
Free Radical Biology and Medicine 87, 204-225, 2015
1362015
The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems
W Flores-Santana, DJ Salmon, S Donzelli, CH Switzer, D Basudhar, ...
Antioxidants & redox signaling 14 (9), 1659-1674, 2011
1082011
Evidence against stable protein S-nitrosylation as a widespread mechanism of post-translational regulation
K Wolhuter, HJ Whitwell, CH Switzer, JR Burgoyne, JF Timms, P Eaton
Molecular cell 69 (3), 438-450. e5, 2018
992018
Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine
S Donzelli, MG Espey, W Flores-Santana, CH Switzer, GC Yeh, J Huang, ...
Free Radical Biology and Medicine 45 (5), 578-584, 2008
992008
Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer
CH Switzer, RYS Cheng, LA Ridnour, SA Glynn, S Ambs, DA Wink
Breast Cancer Research 14, 1-13, 2012
952012
The chemical properties of nitric oxide and related nitrogen oxides
JM Fukuto, JY Cho, CH Switzer
Nitric Oxide, 23-40, 2000
902000
Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation
LA Ridnour, KM Barasch, AN Windhausen, TH Dorsey, MM Lizardo, ...
Public Library of Science 7 (9), e44081, 2012
852012
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