| Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9 X Ren, J Sun, BE Housden, Y Hu, C Roesel, S Lin, LP Liu, Z Yang, D Mao, ... Proceedings of the National Academy of Sciences 110 (47), 19012-19017, 2013 | 421 | 2013 |
| Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila X Ren, Z Yang, J Xu, J Sun, D Mao, Y Hu, SJ Yang, HH Qiao, X Wang, ... Cell reports 9 (3), 1151-1162, 2014 | 331 | 2014 |
| Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes M Song, X Yang, X Ren, L Maliskova, B Li, IR Jones, C Wang, F Jacob, ... Nature genetics 51 (8), 1252-1262, 2019 | 162 | 2019 |
| Phosphatidylserine externalization results from and causes neurite degeneration in Drosophila ML Sapar, H Ji, B Wang, AR Poe, K Dubey, X Ren, JQ Ni, C Han Cell reports 24 (9), 2273-2286, 2018 | 83 | 2018 |
| Optimized strategy for in vivo Cas9-activation in Drosophila B Ewen-Campen, D Yang-Zhou, VR Fernandes, DP González, LP Liu, ... Proceedings of the National Academy of Sciences 114 (35), 9409-9414, 2017 | 82 | 2017 |
| miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila XP Xiong, K Kurthkoti, KY Chang, JL Li, X Ren, JQ Ni, TM Rana, R Zhou PLoS pathogens 12 (11), e1006034, 2016 | 69 | 2016 |
| Performance of the Cas9 Nickase System in Drosophila melanogaster X Ren, Z Yang, D Mao, Z Chang, HH Qiao, X Wang, J Sun, Q Hu, Y Cui, ... G3: Genes, Genomes, Genetics 4 (10), 1955-1962, 2014 | 57 | 2014 |
| A toolkit of CRISPR-based genome editing systems in Drosophila J Xu, X Ren, J Sun, X Wang, HH Qiao, BW Xu, LP Liu, JQ Ni Journal of Genetics and Genomics 42 (4), 141-149, 2015 | 56 | 2015 |
| Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM Y Jia, RG Xu, X Ren, B Ewen-Campen, R Rajakumar, J Zirin, ... Proceedings of the National Academy of Sciences 115 (18), 4719-4724, 2018 | 51 | 2018 |
| An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila HH Qiao, F Wang, RG Xu, J Sun, R Zhu, D Mao, X Ren, X Wang, Y Jia, ... Nature communications 9 (1), 4160, 2018 | 47 | 2018 |
| Histone H1-mediated epigenetic regulation controls germline stem cell self-renewal by modulating H4K16 acetylation J Sun, HM Wei, J Xu, JF Chang, Z Yang, X Ren, WW Lv, LP Liu, LX Pan, ... Nature communications 6 (1), 8856, 2015 | 41 | 2015 |
| Genome editing in Drosophila melanogaster: from basic genome engineering to the multipurpose CRISPR-Cas9 system X Ren, K Holsteens, H Li, J Sun, Y Zhang, LP Liu, Q Liu, JQ Ni Science China Life Sciences 60, 476-489, 2017 | 24 | 2017 |
| Genetically encoded chemical crosslinking of RNA in vivo W Sun, N Wang, H Liu, B Yu, L Jin, X Ren, Y Shen, L Wang Nature chemistry 15 (1), 21-32, 2023 | 23 | 2023 |
| Heterochromatin remodeling by CDK12 contributes to learning in Drosophila L Pan, W Xie, KL Li, Z Yang, J Xu, W Zhang, LP Liu, X Ren, Z He, J Wu, ... Proceedings of the National Academy of Sciences 112 (45), 13988-13993, 2015 | 21 | 2015 |
| Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath X Ren, M Wang, B Li, K Jamieson, L Zheng, IR Jones, B Li, MA Takagi, ... Science advances 7 (38), eabi4360, 2021 | 19 | 2021 |
| Histone H1 defect in escort cells triggers germline tumor in Drosophila ovary Z Yang, J Sun, Y Hu, F Wang, X Wang, HH Qiao, J Xu, D Mao, X Ren, ... Developmental biology 424 (1), 40-49, 2017 | 16 | 2017 |
| The Lysine Demethylase dKDM2 Is Non-essential for Viability, but Regulates Circadian Rhythms in Drosophila Y Zheng, Y Xue, X Ren, M Liu, X Li, Y Jia, Y Niu, JQ Ni, Y Zhang, JY Ji Frontiers in genetics 9, 354, 2018 | 15 | 2018 |
| The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription X Li, M Liu, X Ren, N Loncle, Q Wang, RUS Hemba-Waduge, SH Yu, ... PLoS genetics 16 (5), e1008832, 2020 | 10 | 2020 |
| MiR-315 is required for neural development and represses the expression of dFMR1 in Drosophila melanogaster L Yuan, X Ren, Y Zheng, J Qian, L Xu, M Sun Biochemical and Biophysical Research Communications 525 (2), 469-476, 2020 | 10 | 2020 |
| Functional characterization of Alzheimer’s disease genetic variants in microglia X Yang, J Wen, H Yang, IR Jones, X Zhu, W Liu, B Li, CD Clelland, W Luo, ... Nature Genetics 55 (10), 1735-1744, 2023 | 8 | 2023 |
Yin Shen, Ph.D.Associate Professor, University of California, San FranciscoVerified email at ucsf.edu
