Gary B. Evans
TitleCited byYear
Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase
A Lewandowicz, PC Tyler, GB Evans, RH Furneaux, VL Schramm
Journal of Biological Chemistry 278 (34), 31465-31468, 2003
1592003
Plasmodium falciparum Purine Nucleoside Phosphorylase crystal structures, immucillin inhibitors, and dual catalytic function
W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ...
Journal of Biological Chemistry 279 (18), 18103-18106, 2004
1542004
Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli
V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ...
Journal of Biological Chemistry 280 (18), 18265-18273, 2005
1512005
Potentiation of methicillin activity against methicillin-resistant Staphylococcus aureus by diterpenes
K Nicolson, G Evans, PW O'Toole
FEMS microbiology letters 179 (2), 233-239, 1999
1461999
Purine-less Death in Plasmodium falciparumInduced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase
GA Kicska, PC Tyler, GB Evans, RH Furneaux, VL Schramm, K Kim
Journal of Biological Chemistry 277 (5), 3226-3231, 2002
1392002
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins
LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ...
Journal of Biological Chemistry 280 (10), 9547-9554, 2005
1222005
Exploring structure− activity relationships of transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (15), 3412-3423, 2003
1122003
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (24), 5271-5276, 2003
1102003
Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum
GA Kicska, PC Tyler, GB Evans, RH Furneaux, K Kim, VL Schramm
Journal of Biological Chemistry 277 (5), 3219-3225, 2002
1082002
Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins
GB Evans, RH Furneaux, TL Hutchison, HS Kezar, PE Morris, ...
The Journal of organic chemistry 66 (17), 5723-5730, 2001
952001
Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction
GB Evans, RH Furneaux, PC Tyler, VL Schramm
Organic letters 5 (20), 3639-3640, 2003
932003
Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases
GB Evans, RH Furneaux, GJ Gainsford, VL Schramm, PC Tyler
Tetrahedron 56 (19), 3053-3062, 2000
912000
Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases
RW Miles, PC Tyler, GB Evans, RH Furneaux, DW Parkin, VL Schramm
Biochemistry 38 (40), 13147-13154, 1999
881999
Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases
GB Evans, RH Furneaux, B Greatrex, AS Murkin, VL Schramm, PC Tyler
Journal of medicinal chemistry 51 (4), 948-956, 2008
802008
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
GA Kicska, PC Tyler, GB Evans, RH Furneaux, W Shi, A Fedorov, ...
Biochemistry 41 (49), 14489-14498, 2002
802002
Structural rationale for the affinity of pico-and femtomolar transition state analogues of Escherichia coli 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase
JE Lee, V Singh, GB Evans, PC Tyler, RH Furneaux, KA Cornell, ...
Journal of Biological Chemistry 280 (18), 18274-18282, 2005
762005
Picomolar transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase and X-ray structure with MT-Immucillin-A
V Singh, W Shi, GB Evans, PC Tyler, RH Furneaux, SC Almo, ...
Biochemistry 43 (1), 9-18, 2004
742004
Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases
K Clinch, GB Evans, GWJ Fleet, RH Furneaux, SW Johnson, DH Lenz, ...
Organic & biomolecular chemistry 4 (6), 1131-1139, 2006
732006
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase
K Clinch, GB Evans, RFG Fröhlich, RH Furneaux, PM Kelly, L Legentil, ...
Journal of medicinal chemistry 52 (4), 1126-1143, 2009
712009
Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae
V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ...
Biochemistry 45 (43), 12929-12941, 2006
712006
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