| MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein HJ Cho, G Liu, SM Jin, L Parisiadou, C Xie, J Yu, L Sun, B Ma, J Ding, ... Human molecular genetics 22 (3), 608-620, 2013 | 289 | 2013 |
| LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity L Parisiadou, J Yu, C Sgobio, C Xie, G Liu, L Sun, XL Gu, X Lin, ... Nature neuroscience 17 (3), 367-376, 2014 | 203 | 2014 |
| Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of … X Lin, L Parisiadou, C Sgobio, G Liu, J Yu, L Sun, H Shim, XL Gu, J Luo, ... Journal of Neuroscience 32 (27), 9248-9264, 2012 | 197 | 2012 |
| Reduced anxiety and depression-like behaviors in mice lacking GABA transporter subtype 1 GX Liu, GQ Cai, YQ Cai, ZJ Sheng, J Jiang, Z Mei, ZG Wang, L Guo, J Fei Neuropsychopharmacology 32 (7), 1531-1539, 2007 | 144 | 2007 |
| Mutations in GBA2 cause autosomal-recessive cerebellar ataxia with spasticity MB Hammer, G Eleuch-Fayache, LV Schottlaender, H Nehdi, JR Gibbs, ... The American Journal of Human Genetics 92 (2), 245-251, 2013 | 138 | 2013 |
| Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation G Liu, J Yu, J Ding, C Xie, L Sun, I Rudenko, W Zheng, N Sastry, J Luo, ... The Journal of clinical investigation 124 (7), 3032-3046, 2014 | 129 | 2014 |
| Loss of NAD-dependent protein deacetylase sirtuin-2 alters mitochondrial protein acetylation and dysregulates mitophagy G Liu, SH Park, M Imbesi, WJ Nathan, X Zou, Y Zhu, H Jiang, L Parisiadou, ... Antioxidants & redox signaling 26 (15), 849-863, 2017 | 126 | 2017 |
| SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth SH Park, O Ozden, G Liu, HY Song, Y Zhu, Y Yan, X Zou, HJ Kang, ... Cancer research 76 (13), 3802-3812, 2016 | 109 | 2016 |
| Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER–Golgi export HJ Cho, J Yu, C Xie, P Rudrabhatla, X Chen, J Wu, L Parisiadou, G Liu, ... The EMBO journal 33 (20), 2314-2331, 2014 | 88 | 2014 |
| SIRT3-mediated dimerization of IDH2 directs cancer cell metabolism and tumor growth X Zou, Y Zhu, SH Park, G Liu, J O'Brien, H Jiang, D Gius Cancer research 77 (15), 3990-3999, 2017 | 76 | 2017 |
| A calcineurin-and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons J Luo, L Sun, X Lin, G Liu, J Yu, L Parisiadou, C Xie, J Ding, H Cai Human molecular genetics 23 (24), 6567-6574, 2014 | 72 | 2014 |
| γ-aminobutyric acid transporter 1 negatively regulates T cell-mediated immune responses and ameliorates autoimmune inflammation in the CNS Y Wang, D Feng, G Liu, Q Luo, Y Xu, S Lin, J Fei, L Xu The Journal of Immunology 181 (12), 8226-8236, 2008 | 61 | 2008 |
| α-synuclein, LRRK2 and their interplay in Parkinson’s disease G Liu, L Aliaga, H Cai Future neurology 7 (2), 145-153, 2012 | 57 | 2012 |
| Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine … G Liu, C Sgobio, X Gu, L Sun, X Lin, J Yu, L Parisiadou, C Xie, N Sastry, ... Human molecular genetics 24 (18), 5299-5312, 2015 | 56 | 2015 |
| Mice with genetically altered GABA transporter subtype I (GAT1) expression show altered behavioral responses to ethanol YQ Cai, GQ Cai, GX Liu, Q Cai, JH Shi, J Shi, SK Ma, X Sun, ZJ Sheng, ... Journal of neuroscience research 84 (2), 255-267, 2006 | 56 | 2006 |
| Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease H Cai, G Liu, L Sun, J Ding Translational neurodegeneration 3, 1-7, 2014 | 51 | 2014 |
| Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter Y Zhu, X Zou, AE Dean, JO Brien, Y Gao, EL Tran, SH Park, G Liu, ... Nature communications 10 (1), 2399, 2019 | 43 | 2019 |
| Reduced aggression in mice lacking GABA transporter subtype 1 GX Liu, S Liu, GQ Cai, ZJ Sheng, YQ Cai, J Jiang, X Sun, SK Ma, L Wang, ... Journal of neuroscience research 85 (3), 649-655, 2007 | 39 | 2007 |
| Enhanced learning and memory in GAT1 heterozygous mice J Shi, Y Cai, G Liu, N Gong, Z Liu, T Xu, Z Wang, J Fei Acta Biochim Biophys Sin 44 (4), 359-366, 2012 | 30 | 2012 |
| Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS HX Deng, H Zhai, Y Shi, G Liu, J Lowry, B Liu, ÉB Ryan, J Yan, Y Yang, ... Communications biology 4 (1), 396, 2021 | 25 | 2021 |
Huaibin CaiSenior Investigator, National Institute on Aging, National Institutes of HealthVerified email at mail.nih.gov
