Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility M Parkes, JC Barrett, NJ Prescott, M Tremelling, CA Anderson, SA Fisher, ... Nature genetics 39 (7), 830-832, 2007 | 1435 | 2007 |
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ... The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019 | 568 | 2019 |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease SA Fisher, M Tremelling, CA Anderson, R Gwilliam, S Bumpstead, ... Nature genetics 40 (6), 710-712, 2008 | 547 | 2008 |
The pattern and outcome of acute severe colitis LC Dinesen, AJ Walsh, MN Protic, G Heap, F Cummings, BF Warren, ... Journal of Crohn's and Colitis 4 (4), 431-437, 2010 | 379 | 2010 |
Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis P Bowness, A Ridley, J Shaw, AT Chan, I Wong-Baeza, M Fleming, ... The Journal of Immunology 186 (4), 2672-2680, 2011 | 367 | 2011 |
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ... Gastroenterology 158 (1), 189-199, 2020 | 309 | 2020 |
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease M Tremelling, F Cummings, SA Fisher, J Mansfield, R Gwilliam, A Keniry, ... Gastroenterology 132 (5), 1657-1664, 2007 | 269 | 2007 |
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD NA Kennedy, S Lin, JR Goodhand, N Chanchlani, B Hamilton, ... Gut 70 (10), 1884-1893, 2021 | 257 | 2021 |
QT and QTc dispersion are accurate predictors of cardiac death in newly diagnosed non-insulin dependent diabetes: cohort study AAO Naas, NC Davidson, C Thompson, F Cummings, SA Ogston, ... Bmj 316 (7133), 745-746, 1998 | 215 | 1998 |
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants GA Heap, MN Weedon, CM Bewshea, A Singh, M Chen, JB Satchwell, ... Nature genetics 46 (10), 1131-1134, 2014 | 212 | 2014 |
Biosimilar infliximab in inflammatory bowel disease: outcomes of a managed switching programme V Razanskaite, M Bettey, L Downey, J Wright, J Callaghan, M Rush, ... Journal of Crohn's and Colitis 11 (6), 690-696, 2017 | 180 | 2017 |
Confirmation of the role of ATG16l1 as a Crohn's disease susceptibility gene FJR Cummings, R Cooney, S Pathan, CA Anderson, JC Barrett, J Beckly, ... Inflammatory bowel diseases 13 (8), 941-946, 2007 | 156 | 2007 |
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype FJR Cummings, T Ahmad, A Geremia, J Beckly, R Cooney, L Hancock, ... Inflammatory bowel diseases 13 (9), 1063-1068, 2007 | 126 | 2007 |
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease GA Heap, K So, M Weedon, N Edney, C Bewshea, A Singh, V Annese, ... Journal of Crohn's and Colitis 10 (2), 149-158, 2016 | 115 | 2016 |
Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial C Mowat, I Arnott, A Cahill, M Smith, T Ahmad, S Subramanian, S Travis, ... The lancet Gastroenterology & hepatology 1 (4), 273-282, 2016 | 110 | 2016 |
Oral methotrexate in ulcerative colitis JRF Cummings, KR Herrlinger, SPL Travis, DA Gorard, AS McIntyre, ... Alimentary pharmacology & therapeutics 21 (4), 385-389, 2005 | 95 | 2005 |
Medical management of Crohn’s disease JRF Cummings, S Keshav, SPL Travis Bmj 336 (7652), 1062-1066, 2008 | 94 | 2008 |
The pharmacogenetics of methotrexate in inflammatory bowel disease KR Herrlinger, JRF Cummings, MCNM Barnardo, M Schwab, T Ahmad, ... Pharmacogenetics and genomics 15 (10), 705-711, 2005 | 87 | 2005 |
The genetics of NOD‐like receptors in Crohn's disease JRF Cummings, RM Cooney, G Clarke, J Beckly, A Geremia, S Pathan, ... Tissue antigens 76 (1), 48-56, 2010 | 86 | 2010 |
How have patients reacted to the implications of the DCCT? CJ Thompson, JF Cummings, J Chalmers, C Gould, RW Newton Diabetes care 19 (8), 876-879, 1996 | 86 | 1996 |