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Tet Woo Lee
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Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
SMF Jamieson, P Tsai, MK Kondratyev, P Budhani, A Liu, NN Senzer, ...
JCI insight 3 (16), 2018
582018
Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system
TW Lee, VWK Tsang, NP Birch
Frontiers in cellular neuroscience 9, 396, 2015
492015
Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules
TW Lee, VWK Tsang, NP Birch
Neuron glia biology 4 (3), 223-234, 2008
492008
Physiological and pathological functions of neuroserpin: regulation of cellular responses through multiple mechanisms
TW Lee, VWK Tsang, EJ Loef, NP Birch
Seminars in cell & developmental biology 62, 152-159, 2017
462017
Neuroserpin regulates the density of dendritic protrusions and dendritic spine shape in cultured hippocampal neurons
VM Borges, TW Lee, DL Christie, NP Birch
Journal of neuroscience research 88 (12), 2610-2617, 2010
462010
Neuroserpin regulates N‐cadherin‐mediated cell adhesion independently of its activity as an inhibitor of tissue plasminogen activator
TW Lee, LC Coates, NP Birch
Journal of neuroscience research 86 (6), 1243-1253, 2008
462008
Radiosensitization of head and neck squamous cell carcinoma lines by DNA-PK inhibitors is more effective than PARP-1 inhibition and is enhanced by SLFN11 and hypoxia
TW Lee, WW Wong, BD Dickson, B Lipert, GJ Cheng, FW Hunter, MP Hay, ...
International journal of radiation biology 95 (12), 1597-1612, 2019
392019
Chemicals eluting from disposable plastic syringes and syringe filters alter neurite growth, axogenesis and the microtubule cytoskeleton in cultured hippocampal neurons
TW Lee, S Tumanov, SG Villas‐Bôas, JM Montgomery, NP Birch
Journal of neurochemistry 133 (1), 53-65, 2015
322015
Patient-derived xenograft and organoid models for precision medicine targeting of the tumour microenvironment in head and neck cancer
TW Lee, A Lai, JK Harms, DC Singleton, BD Dickson, AMJ Macann, ...
Cancers 12 (12), 3743, 2020
292020
Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage
SA Kennedy, AC Van Diepen, CM Van Den Hurk, LC Coates, TW Lee, ...
Thrombosis and haemostasis 97 (03), 394-399, 2007
262007
Impact of tumour hypoxia on evofosfamide sensitivity in head and neck squamous cell carcinoma patient-derived xenograft models
JK Harms, TW Lee, T Wang, A Lai, D Kee, JM Chaplin, NP McIvor, ...
Cells 8 (7), 717, 2019
202019
Retracted: The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non‐inhibitory mechanism
TW Lee, JM Montgomery, NP Birch
Journal of neurochemistry 121 (4), 561-574, 2012
202012
Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons
SD Robinson, TW Lee, DL Christie, NP Birch
Frontiers in Cellular Neuroscience 9, 404, 2015
112015
An analysis approach to identify specific functional sites in orthologous proteins using sequence and structural information: application to neuroserpin reveals regions that …
TW Lee, ASP Yang, T Brittain, NP Birch
Proteins: Structure, Function, and Bioinformatics 83 (1), 135-152, 2015
102015
Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models
TW Lee, DC Singleton, JK Harms, M Lu, SP McManaway, A Lai, M Tercel, ...
Molecular Oncology, 2024
22024
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
SMF Jamieson, P Tsai, MK Kondratyev, P Budhani, A Liu, NN Senzer, ...
JCI insight 8 (4), 2023
22023
Random clonal expansion as a limiting factor in transplantable in vivo CRISPR/Cas9 screens
TW Lee, FW Hunter, WR Wilson, SMF Jamieson
bioRxiv, 2021.11. 28.469740, 2021
22021
Fragment-based and structure-guided discovery of perforin inhibitors
J Jose, RHP Law, EWW Leung, DCC Wai, H Akhlaghi, ...
European Journal of Medicinal Chemistry 261, 115786, 2023
12023
Identification of TSC1 and TSC2 as potential determinants of sensitivity to trastuzumab emtansine
FW Hunter, BA Lipert, KN Siemens, A Khan, HR Barker, TW Ketela, ...
Cancer Research 80 (16_Supplement), 5853-5853, 2020
12020
Identification of glucose-6-phosphate dehydrogenase dependency in IDH1 mutant glioma cells using functional genomics
KM Paras, P Patel, P Choi, WR Wilson, TW Lee, SM Jamieson, ...
Cancer Research 84 (6_Supplement), 4333-4333, 2024
2024
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Articles 1–20