Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma SMF Jamieson, P Tsai, MK Kondratyev, P Budhani, A Liu, NN Senzer, ... JCI insight 3 (16), 2018 | 58 | 2018 |
Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system TW Lee, VWK Tsang, NP Birch Frontiers in cellular neuroscience 9, 396, 2015 | 49 | 2015 |
Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules TW Lee, VWK Tsang, NP Birch Neuron glia biology 4 (3), 223-234, 2008 | 49 | 2008 |
Physiological and pathological functions of neuroserpin: regulation of cellular responses through multiple mechanisms TW Lee, VWK Tsang, EJ Loef, NP Birch Seminars in cell & developmental biology 62, 152-159, 2017 | 46 | 2017 |
Neuroserpin regulates the density of dendritic protrusions and dendritic spine shape in cultured hippocampal neurons VM Borges, TW Lee, DL Christie, NP Birch Journal of neuroscience research 88 (12), 2610-2617, 2010 | 46 | 2010 |
Neuroserpin regulates N‐cadherin‐mediated cell adhesion independently of its activity as an inhibitor of tissue plasminogen activator TW Lee, LC Coates, NP Birch Journal of neuroscience research 86 (6), 1243-1253, 2008 | 46 | 2008 |
Radiosensitization of head and neck squamous cell carcinoma lines by DNA-PK inhibitors is more effective than PARP-1 inhibition and is enhanced by SLFN11 and hypoxia TW Lee, WW Wong, BD Dickson, B Lipert, GJ Cheng, FW Hunter, MP Hay, ... International journal of radiation biology 95 (12), 1597-1612, 2019 | 39 | 2019 |
Chemicals eluting from disposable plastic syringes and syringe filters alter neurite growth, axogenesis and the microtubule cytoskeleton in cultured hippocampal neurons TW Lee, S Tumanov, SG Villas‐Bôas, JM Montgomery, NP Birch Journal of neurochemistry 133 (1), 53-65, 2015 | 32 | 2015 |
Patient-derived xenograft and organoid models for precision medicine targeting of the tumour microenvironment in head and neck cancer TW Lee, A Lai, JK Harms, DC Singleton, BD Dickson, AMJ Macann, ... Cancers 12 (12), 3743, 2020 | 29 | 2020 |
Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage SA Kennedy, AC Van Diepen, CM Van Den Hurk, LC Coates, TW Lee, ... Thrombosis and haemostasis 97 (03), 394-399, 2007 | 26 | 2007 |
Impact of tumour hypoxia on evofosfamide sensitivity in head and neck squamous cell carcinoma patient-derived xenograft models JK Harms, TW Lee, T Wang, A Lai, D Kee, JM Chaplin, NP McIvor, ... Cells 8 (7), 717, 2019 | 20 | 2019 |
Retracted: The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non‐inhibitory mechanism TW Lee, JM Montgomery, NP Birch Journal of neurochemistry 121 (4), 561-574, 2012 | 20 | 2012 |
Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons SD Robinson, TW Lee, DL Christie, NP Birch Frontiers in Cellular Neuroscience 9, 404, 2015 | 11 | 2015 |
An analysis approach to identify specific functional sites in orthologous proteins using sequence and structural information: application to neuroserpin reveals regions that … TW Lee, ASP Yang, T Brittain, NP Birch Proteins: Structure, Function, and Bioinformatics 83 (1), 135-152, 2015 | 10 | 2015 |
Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models TW Lee, DC Singleton, JK Harms, M Lu, SP McManaway, A Lai, M Tercel, ... Molecular Oncology, 2024 | 2 | 2024 |
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma SMF Jamieson, P Tsai, MK Kondratyev, P Budhani, A Liu, NN Senzer, ... JCI insight 8 (4), 2023 | 2 | 2023 |
Random clonal expansion as a limiting factor in transplantable in vivo CRISPR/Cas9 screens TW Lee, FW Hunter, WR Wilson, SMF Jamieson bioRxiv, 2021.11. 28.469740, 2021 | 2 | 2021 |
Fragment-based and structure-guided discovery of perforin inhibitors J Jose, RHP Law, EWW Leung, DCC Wai, H Akhlaghi, ... European Journal of Medicinal Chemistry 261, 115786, 2023 | 1 | 2023 |
Identification of TSC1 and TSC2 as potential determinants of sensitivity to trastuzumab emtansine FW Hunter, BA Lipert, KN Siemens, A Khan, HR Barker, TW Ketela, ... Cancer Research 80 (16_Supplement), 5853-5853, 2020 | 1 | 2020 |
Identification of glucose-6-phosphate dehydrogenase dependency in IDH1 mutant glioma cells using functional genomics KM Paras, P Patel, P Choi, WR Wilson, TW Lee, SM Jamieson, ... Cancer Research 84 (6_Supplement), 4333-4333, 2024 | | 2024 |