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Sebastien Malinge
Sebastien Malinge
Telethon Kids Institute - Cancer Centre, Senior Research Fellow
Verified email at telethonkids.org.au
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Cited by
Cited by
Year
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
O Abdel-Wahab, A Mullally, C Hedvat, G Garcia-Manero, J Patel, ...
Blood, The Journal of the American Society of Hematology 114 (1), 144-147, 2009
8342009
Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome
S Malinge, S Izraeli, JD Crispino
Blood, The Journal of the American Society of Hematology 113 (12), 2619-2628, 2009
2862009
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
E Ansó, SE Weinberg, LP Diebold, BJ Thompson, S Malinge, ...
Nature cell biology 19 (6), 614-625, 2017
2682017
Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome
S Malinge, M Bliss-Moreau, G Kirsammer, L Diebold, T Chlon, ...
The Journal of clinical investigation 122 (3), 948-962, 2012
1882012
Activating mutations in human acute megakaryoblastic leukemia
S Malinge, C Ragu, V Della-Valle, D Pisani, SN Constantinescu, C Perez, ...
Blood, The Journal of the American Society of Hematology 112 (10), 4220-4226, 2008
1682008
Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition
Q Jeremy Wen, Q Yang, B Goldenson, S Malinge, T Lasho, RK Schneider, ...
Nature medicine 21 (12), 1473-1480, 2015
1522015
Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia
S Malinge, R Ben-Abdelali, C Settegrana, I Radford-Weiss, M Debre, ...
Blood 109 (5), 2202-2204, 2007
1512007
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation
AA Lane, B Chapuy, CY Lin, T Tivey, H Li, EC Townsend, ...
Nature genetics 46 (6), 618-623, 2014
1472014
Myeloid leukemia in Down syndrome
I Khan, S Malinge, J Crispino
Critical Reviews™ in Oncogenesis 16 (1-2), 2011
1422011
A subgroup of malignant fibrous histiocytomas is associated with genetic changes similar to those of well-differentiated liposarcomas
F Chibon, O Mariani, J Derré, S Malinge, JM Coindre, L Guillou, R Lagacé, ...
Cancer genetics and cytogenetics 139 (1), 24-29, 2002
1212002
DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3
BJ Thompson, R Bhansali, L Diebold, DE Cook, L Stolzenburg, ...
Journal of Experimental Medicine 212 (6), 953-970, 2015
872015
ETO2-GLIS2 hijacks transcriptional complexes to drive cellular identity and self-renewal in pediatric acute megakaryoblastic leukemia
C Thirant, C Ignacimouttou, CK Lopez, L Le Mouël, C Thiollier, A Siret, ...
Cancer cell 31 (3), 452-465, 2017
752017
A CHAF1B-dependent molecular switch in hematopoiesis and leukemia pathogenesis
A Volk, K Liang, P Suraneni, X Li, J Zhao, M Bulic, S Marshall, K Pulakanti, ...
Cancer cell 34 (5), 707-723. e7, 2018
692018
Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling
S Malinge, C Thiollier, TM Chlon, LC Doré, L Diebold, O Bluteau, ...
Blood, The Journal of the American Society of Hematology 121 (13), 2440-2451, 2013
602013
DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3
RS Bhansali, M Rammohan, P Lee, AP Laurent, Q Wen, P Suraneni, ...
The Journal of Clinical Investigation 131 (1), 2021
562021
Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes
S Malinge, T Chlon, LC Doré, RP Ketterling, MS Tallman, E Paietta, ...
Blood, The Journal of the American Society of Hematology 122 (14), e33-e43, 2013
532013
Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome
AP Laurent, RS Kotecha, S Malinge
Leukemia 34 (8), 1984-1999, 2020
512020
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene–driven myeloid leukemia
CK Lopez, E Noguera, V Stavropoulou, E Robert, Z Aid, P Ballerini, ...
Cancer discovery 9 (12), 1736-1753, 2019
432019
Activation of the NF-κB pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKKα
S Malinge, R Monni, O Bernard, V Penard-Lacronique
Oncogene 25 (25), 3589-3597, 2006
382006
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers
A Fagnan, FO Bagger, MR Piqué-Borràs, C Ignacimouttou, A Caulier, ...
Blood, The Journal of the American Society of Hematology 136 (6), 698-714, 2020
332020
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