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Norberto Gonzalez-Juarbe
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Pore-forming toxins induce macrophage necroptosis during acute bacterial pneumonia
N González-Juarbe, RP Gilley, CA Hinojosa, KM Bradley, A Kamei, G Gao, ...
PLoS pathogens 11 (12), e1005337, 2015
2272015
NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis
D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun, CJ Orihuela, M Niederweis
Cell reports 24 (2), 429-440, 2018
1572018
Severe pneumococcal pneumonia causes acute cardiac toxicity and subsequent cardiac remodeling
LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, A Anzueto, BL Babu, ...
American Journal of Respiratory and Critical Care Medicine 196 (5), 609-620, 2017
1212017
Streptococcus pneumoniae biofilm formation is strain dependent, multifactorial, and associated with reduced invasiveness and immunoreactivity during colonization
K Blanchette-Cain, CA Hinojosa, R Akula Suresh Babu, A Lizcano, ...
MBio 4 (5), 10.1128/mbio. 00745-13, 2013
1142013
Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia
N González-Juarbe, KM Bradley, AT Shenoy, RP Gilley, LF Reyes, ...
Cell Death & Differentiation 24 (5), 917-928, 2017
962017
Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing
AT Shenoy, T Brissac, RP Gilley, N Kumar, Y Wang, N Gonzalez-Juarbe, ...
PLoS pathogens 13 (8), e1006582, 2017
662017
Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion
RP Gilley, N González-Juarbe, AT Shenoy, LF Reyes, PH Dube, ...
Infection and immunity 84 (5), 1457-1469, 2016
652016
Killing of Serratia marcescens biofilms with chloramphenicol
C Ray, AT Shenoy, CJ Orihuela, N González-Juarbe
Annals of clinical microbiology and antimicrobials 16, 1-6, 2017
502017
Bacterial pore-forming toxins promote the activation of caspases in parallel to necroptosis to enhance alarmin release and inflammation during pneumonia
N Gonzalez-Juarbe, KM Bradley, AN Riegler, LF Reyes, T Brissac, ...
Scientific reports 8 (1), 5846, 2018
412018
A non-human primate model of severe pneumococcal pneumonia
LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, AT Shenoy, RP Gilley, ...
PloS one 11 (11), e0166092, 2016
412016
Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumonia
N González-Juarbe, CA Mares, CA Hinojosa, JL Medina, A Cantwell, ...
Infection and immunity 83 (2), 614-624, 2015
402015
Necroptotic cell death promotes adaptive immunity against colonizing pneumococci
AN Riegler, T Brissac, N Gonzalez-Juarbe, CJ Orihuela
Frontiers in Immunology 10, 443117, 2019
372019
Influenza-induced oxidative stress sensitizes lung cells to bacterial-toxin-mediated necroptosis
N Gonzalez-Juarbe, AN Riegler, AS Jureka, RP Gilley, JD Brand, ...
Cell reports 32 (8), 2020
332020
NAD hydrolysis by the tuberculosis necrotizing toxin induces lethal oxidative stress in macrophages
D Pajuelo, N Gonzalez‐Juarbe, M Niederweis
Cellular microbiology 22 (1), e13115, 2020
282020
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza
SS Park, N Gonzalez-Juarbe, AN Riegler, H Im, Y Hale, MP Platt, ...
Cell reports 35 (11), 2021
242021
Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia
CA Hinojosa, N Gonzalez-Juarbe, MM Rahman, G Fernandes, ...
Microbial pathogenesis 141, 103979, 2020
222020
Kinetic multi-omic analysis of responses to SARS-CoV-2 infection in a model of severe COVID-19
AM Cantwell, H Singh, M Platt, Y Yu, YH Lin, Y Ikeno, G Hubbard, Y Xiang, ...
Journal of virology 95 (20), 10.1128/jvi. 01010-21, 2021
202021
Streptococcus pneumoniae binds to host lactate dehydrogenase via PspA and PspC to enhance virulence
SS Park, N Gonzalez-Juarbe, E Martínez, JY Hale, YH Lin, JT Huffines, ...
MBio 12 (3), 10.1128/mbio. 00673-21, 2021
192021
Global proteome and phosphoproteome characterization of sepsis-induced kidney injury
YH Lin, MP Platt, H Fu, Y Gui, Y Wang, N Gonzalez-Juarbe, D Zhou, Y Yu
Molecular & Cellular Proteomics 19 (12), 2030-2047, 2020
192020
Inhibition of necroptosis to prevent long-term cardiac damage during pneumococcal pneumonia and invasive disease
SM Beno, AN Riegler, RP Gilley, T Brissac, Y Wang, KL Kruckow, ...
The Journal of infectious diseases 222 (11), 1882-1893, 2020
172020
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Articles 1–20