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EKANAYAKE, A. I.
EKANAYAKE, A. I.
Verified email at usc.edu
Title
Cited by
Cited by
Year
Genetically encoded fragment-based discovery from phage-displayed macrocyclic libraries with genetically encoded unnatural pharmacophores
AI Ekanayake, L Sobze, P Kelich, J Youk, NJ Bennett, R Mukherjee, ...
Journal of the American Chemical Society 143 (14), 5497-5507, 2021
462021
A chemical-genetic approach to generate selective covalent inhibitors of protein kinases
A Kung, M Schimpl, A Ekanayake, YC Chen, R Overman, C Zhang
ACS chemical biology 12 (6), 1499-1503, 2017
252017
Targeting CTP synthetase 1 to restore interferon induction and impede nucleotide synthesis in SARS-CoV-2 infection
Y Rao, TY Wang, C Qin, B Espinosa, Q Liu, A Ekanayake, J Zhao, ...
BioRxiv, 2021
132021
Synthesis and target identification of a novel electrophilic warhead, 2-chloromethylquinoline
F Ni, A Ekanayake, B Espinosa, C Yu, JN Sanders, J Perino, KN Houk, ...
Biochemistry 58 (24), 2715-2719, 2019
102019
Genetically encoded fragment-based discovery (GE-FBD) from phage-displayed macrocyclic libraries with genetically-encoded unnatural pharmacophores
A Ekanayake, L Sobze, J Youk, NJ Bennett, R Mukherjee, A Bhardwaj, ...
32020
Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivo
JYK Wong, AI Ekanayake, S Kharchenko, SE Kirberger, R Qiu, P Kelich, ...
Nature communications 14 (1), 5654, 2023
12023
Late-stage reshaping of phage-displayed libraries to macrocyclic and bicyclic landscapes using multipurpose linchpin
K Yan, M Miskolzie, FB Mejia, C Peng, AI Ekanayake, DJ Maly, R Derda
2024
Late-stage reshaping of phage-displayed libraries to macrocyclic and bicyclic landscapes using multipurpose linchpin
R Derda, K Yan, M Miskolzie, FB Mejia, DJ Maly, AI Ekanayake, C Peng
2024
Identification of Covalent Ligands – from Single Targets to Whole Proteome
PCZ Chau Ngo, Dr. Arunika Ekanayake
Israel Journal of Chemistry, e202200105, 2023
2023
Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection (preprint)
Y Rao, TY Wang, C Qin, B Espinosa, Q Liu, A Ekanayake, J Zhao, ...
2021
GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE
R DERDA, A MUKHERJEE, RAJA, EKANAYAKE
WO Patent WO/2020/107,118, 2020
2020
NOVEL INHIBITORS OF GUANOSINE MONOPHOSPHATE SYNTHETASE AS THERAPEUTIC AGENTS
C ZHANG, F NI, A EKANAYAKE, B ESPINOSA
WO Patent WO/2020/055,504, 2020
2020
Chemoproteomic approach for discovering covalent ligands for diverse protein targets
C Zhang, F Ni, AI Ekanayake
US Patent App. 16/339,621, 2020
2020
Exploration of target space of electrophilic quinazolines
B Espinosa, A Ekanayake, C Zhang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
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