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Laurent Verkoczy
Laurent Verkoczy
Professor, San Diego Biomedical Research Institute
Verified email at SDBRI.org
Title
Cited by
Cited by
Year
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
L Verkoczy, M Diaz, TM Holl, YB Ouyang, H Bouton-Verville, SM Alam, ...
Proceedings of the National Academy of Sciences 107 (1), 181-186, 2010
2292010
Antibody polyspecificity and neutralization of HIV-1: a hypothesis
BF Haynes, MA Moody, L Verkoczy, G Kelsoe, SM Alam
Human antibodies 14 (3-4), 59-67, 2005
2082005
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase ζ
M Diaz, LK Verkoczy, MF Flajnik, N R Klinman
The Journal of Immunology 167 (1), 327-335, 2001
1772001
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
KO Saunders, K Wiehe, M Tian, P Acharya, T Bradley, SM Alam, EP Go, ...
Science 366 (6470), eaay7199, 2019
1262019
Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies
L Verkoczy, G Kelsoe, MA Moody, BF Haynes
Current opinion in immunology 23 (3), 383-390, 2011
1262011
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH× VL knockin mice reveals multiple tolerance controls
L Verkoczy, Y Chen, H Bouton-Verville, J Zhang, M Diaz, J Hutchinson, ...
The Journal of Immunology 187 (7), 3785-3797, 2011
1252011
Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection
L Verkoczy, B Duong, P Skog, D Aït-Azzouzene, K Puri, JL Vela, ...
The Journal of Immunology 178 (10), 6332-6341, 2007
1252007
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
M Bonsignori, K Wiehe, SK Grimm, R Lynch, G Yang, DM Kozink, F Perrin, ...
The Journal of clinical investigation 124 (4), 1835-1843, 2014
1132014
Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies
MA Moody, I Pedroza-Pacheco, NA Vandergrift, C Chui, KE Lloyd, ...
Science immunology 1 (1), aag0851-aag0851, 2016
1052016
A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes
L Verkoczy, D Aït-Azzouzene, P Skog, A Märtensson, J Lang, B Duong, ...
Immunity 22 (4), 519-531, 2005
1022005
Vaccine induction of heterologous tier 2 HIV-1 neutralizing antibodies in animal models
KO Saunders, LK Verkoczy, C Jiang, J Zhang, R Parks, H Chen, ...
Cell reports 21 (13), 3681-3690, 2017
1012017
Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10
Y Chen, J Zhang, KK Hwang, H Bouton-Verville, SM Xia, A Newman, ...
The Journal of Immunology 191 (3), 1260-1275, 2013
1002013
Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages
R Zhang, L Verkoczy, K Wiehe, S Munir Alam, NI Nicely, S Santra, ...
Science translational medicine 8 (336), 336ra62-336ra62, 2016
992016
Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against MPER-associated autoreactivity limits T-dependent responses
L Verkoczy, Y Chen, J Zhang, H Bouton-Verville, A Newman, B Lockwood, ...
The Journal of Immunology 191 (5), 2538-2550, 2013
99*2013
Progress in HIV-1 vaccine development
BF Haynes, MA Moody, M Alam, M Bonsignori, L Verkoczy, G Ferrari, ...
Journal of Allergy and Clinical Immunology 134 (1), 3-10, 2014
872014
Decreased Frequency and Highly Aberrant Spectrum of Ultraviolet-Induced Mutations in the hprt Gene of Mouse Fibroblasts Expressing Antisense RNA to DNA …
M Diaz, NB Watson, G Turkington, LK Verkoczy, NR Klinman, ...
Molecular Cancer Research 1 (11), 836-847, 2003
862003
An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system
D Ait-Azzouzene, L Verkoczy, J Peters, A Gavin, P Skog, JL Vela, ...
The Journal of experimental medicine 201 (5), 817-828, 2005
852005
Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations
WB Williams, J Zhang, C Jiang, NI Nicely, D Fera, K Luo, MA Moody, ...
Nature communications 8 (1), 1732, 2017
822017
HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design
M Bonsignori, SM Alam, HX Liao, L Verkoczy, GD Tomaras, BF Haynes, ...
Trends in microbiology 20 (11), 532-539, 2012
812012
Host controls of HIV neutralizing antibodies
BF Haynes, L Verkoczy
Science 344 (6184), 588-589, 2014
792014
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