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Ashleigh Riegler
Ashleigh Riegler
Verified email at uab.edu
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Year
An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease
A D’Mello, AN Riegler, E Martínez, SM Beno, TD Ricketts, EF Foxman, ...
Proceedings of the National Academy of Sciences 117 (52), 33507-33518, 2020
462020
Bacterial pore-forming toxins promote the activation of caspases in parallel to necroptosis to enhance alarmin release and inflammation during pneumonia
N Gonzalez-Juarbe, KM Bradley, AN Riegler, LF Reyes, T Brissac, ...
Scientific reports 8 (1), 5846, 2018
412018
Necroptotic cell death promotes adaptive immunity against colonizing pneumococci
AN Riegler, T Brissac, N Gonzalez-Juarbe, CJ Orihuela
Frontiers in Immunology 10, 443117, 2019
372019
Influenza-induced oxidative stress sensitizes lung cells to bacterial-toxin-mediated necroptosis
N Gonzalez-Juarbe, AN Riegler, AS Jureka, RP Gilley, JD Brand, ...
Cell reports 32 (8), 2020
332020
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza
SS Park, N Gonzalez-Juarbe, AN Riegler, H Im, Y Hale, MP Platt, ...
Cell reports 35 (11), 2021
252021
Capsule promotes intracellular survival and vascular endothelial cell translocation during invasive pneumococcal disease
T Brissac, E Martínez, KL Kruckow, AN Riegler, F Ganaie, H Im, S Bakshi, ...
MBio 12 (5), 10.1128/mbio. 02516-21, 2021
182021
Inhibition of necroptosis to prevent long-term cardiac damage during pneumococcal pneumonia and invasive disease
SM Beno, AN Riegler, RP Gilley, T Brissac, Y Wang, KL Kruckow, ...
The Journal of infectious diseases 222 (11), 1882-1893, 2020
172020
Anatomical site-specific carbohydrate availability impacts Streptococcus pneumoniae virulence and fitness during colonization and disease
H Im, KL Kruckow, A D’Mello, F Ganaie, E Martinez, JN Luck, KH Cichos, ...
Infection and Immunity 90 (1), e00451-21, 2022
122022
Differential activation of programmed cell death in patients with severe SARS-CoV-2 infection
AN Riegler, P Benson, K Long, SM Leal Jr
Cell Death Discovery 9 (1), 420, 2023
12023
Opening the OPK assay gatekeeper: harnessing multi-modal protection by pneumococcal vaccines
AN Riegler, B Mann, CJ Orihuela, E Tuomanen
Pathogens 8 (4), 203, 2019
12019
Capsule protects against intracellular killing and enables vascular endothelial cell translocation during invasive pneumococcal disease
T Brissac, E Martínez, KL Kruckow, AN Riegler, F Ganaie, H Im, S Bakshi, ...
bioRxiv, 2021.02. 10.430484, 2021
2021
Characterizing the Role of Necroptosis of Airway Epithelial Cells in the Immune Response to Respiratory Pathogens
AN Riegler
The University of Alabama at Birmingham, 2021
2021
MLKL-independent RIPK3 signaling alters adaptive immune responses to IAV pneumonia
AN Riegler, MM Jenkins, A Ballesteros-Tato, CJ Orihuela
The Journal of Immunology 204 (1_Supplement), 93.6-93.6, 2020
2020
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