Tim J. Mitchell
Tim J. Mitchell
Professor of Microbial Infection and Immunity, University of Birmingham
Verified email at - Homepage
Cited by
Cited by
Rapid pneumococcal evolution in response to clinical interventions
NJ Croucher, SR Harris, C Fraser, MA Quail, J Burton, M Van Der Linden, ...
science 331 (6016), 430-434, 2011
A highly conserved repeated DNA element located in the chromosome of Streptococcus pneumoniae
B Martin, O Humbert, M Camara, E Guenzi, J Walker, T Mitchell, P Andrew, ...
Nucleic acids research 20 (13), 3479-3483, 1992
Pneumococcal pneumolysin and H2O2 mediate brain cell apoptosis during meningitis
JS Braun, JE Sublett, D Freyer, TJ Mitchell, JL Cleveland, EI Tuomanen, ...
The Journal of clinical investigation 109 (1), 19-27, 2002
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
C Donati, NL Hiller, H Tettelin, A Muzzi, NJ Croucher, SV Angiuoli, ...
Genome biology 11 (10), 1-19, 2010
The pathogenesis of streptococcal infections: from tooth decay to meningitis
TJ Mitchell
Nature Reviews Microbiology 1 (3), 219-230, 2003
Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: Genetic requirements
S Guiral, TJ Mitchell, B Martin, JP Claverys
Proceedings of the National Academy of Sciences 102 (24), 68, 2005
Streptococcus pneumoniae: virulence factors and variation
AM Mitchell, TJ Mitchell
Clinical Microbiology and Infection 16 (5), 411-418, 2010
Molecular analysis of the pathogenicity of Streptococcus pneumoniae: the role of pneumococcal proteins
JC Paton, PW Andrew, GJ Boulnois, TJ Mitchell
Annual review of microbiology 47, 89-116, 1993
Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae
JE Alexander, RA Lock, CC Peeters, JT Poolman, PW Andrew, TJ Mitchell, ...
Infection and immunity 62 (12), 5683-5688, 1994
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia
M Witzenrath, F Pache, D Lorenz, U Koppe, B Gutbier, C Tabeling, ...
The Journal of Immunology 187 (1), 434-440, 2011
Microarray-Based Identification of a NovelStreptococcus pneumoniae Regulon Controlled by an Autoinduced Peptide
A De Saizieu, C Gardès, N Flint, C Wagner, M Kamber, TJ Mitchell, ...
Journal of Bacteriology 182 (17), 4696-4703, 2000
Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes
S Houldsworth, PW Andrew, TJ Mitchell
Infection and immunity 62 (4), 1501-1503, 1994
The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumococcus
JR Canvin, AP Marvin, M Sivakumaran, JC Paton, GJ Boulnois, ...
Journal of Infectious Diseases 172 (1), 119-123, 1995
Host cellular immune response to pneumococcal lung infection in mice
A Kadioglu, NA Gingles, K Grattan, A Kerr, TJ Mitchell, PW Andrew
Infection and immunity 68 (2), 492-501, 2000
Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute‐phase protein
TJ Mitchell, PW Andrew, FK Saunders, AN Smith, GJ Boulnois
Molecular microbiology 5 (8), 1883-1888, 1991
The biology of Gram-positive sortase enzymes
GK Paterson, TJ Mitchell
Trends in microbiology 12 (2), 89-95, 2004
Pneumolysin: a double-edged sword during the host-pathogen interaction
HM Marriott, TJ Mitchell, DH Dockrell
Current molecular medicine 8 (6), 497-509, 2008
A neuraminidase from Streptococcus pneumoniae has the features of a surface protein
M Camara, GJ Boulnois, PW Andrew, TJ Mitchell
Infection and immunity 62 (9), 3688-3695, 1994
Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide
JC Paton, RA Lock, CJ Lee, JP Li, AM Berry, TJ Mitchell, PW Andrew, ...
Infection and immunity 59 (7), 2297-2304, 1991
Role of Manganese-Containing Superoxide Dismutase in Oxidative Stress and Virulence of Streptococcus pneumoniae
H Yesilkaya, A Kadioglu, N Gingles, JE Alexander, TJ Mitchell, ...
Infection and immunity 68 (5), 2819-2826, 2000
The system can't perform the operation now. Try again later.
Articles 1–20