| Structures of influenza A virus RNA polymerase offer insight into viral genome replication H Fan, AP Walker, L Carrique, JR Keown, I Serna Martin, D Karia, ... Nature 573 (7773), 287-290, 2019 | 165 | 2019 |
| Host ANP32A mediates the assembly of the influenza virus replicase L Carrique, H Fan, AP Walker, JR Keown, J Sharps, E Staller, WS Barclay, ... Nature 587 (7835), 638-643, 2020 | 88 | 2020 |
| An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ... Journal of applied crystallography 51 (1), 97-111, 2018 | 77 | 2018 |
| Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ... Nucleic acids research 50 (3), 1484-1500, 2022 | 51 | 2022 |
| A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins JR Keown, MM Black, A Ferron, M Yap, MJ Barnett, FG Pearce, JP Stoye, ... Journal of Biological Chemistry 293 (47), 18378-18386, 2018 | 51 | 2018 |
| Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins M Renner, W Dejnirattisai, L Carrique, IS Martin, D Karia, SL Ilca, SF Ho, ... Nature Communications 12 (1), 1238, 2021 | 47 | 2021 |
| Small oligomers of ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase are required for biological activity JR Keown, MDW Griffin, HDT Mertens, FG Pearce Journal of Biological Chemistry 288 (28), 20607-20615, 2013 | 44 | 2013 |
| The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme AP Walker, H Fan, JR Keown, ML Knight, JM Grimes, E Fodor Nucleic acids research 49 (22), 13019-13030, 2021 | 40 | 2021 |
| Characterization of spinach ribulose-1, 5-bisphosphate carboxylase/oxygenase activase isoforms reveals hexameric assemblies with increased thermal stability JR Keown, FG Pearce Biochemical Journal 464 (3), 413-423, 2014 | 38 | 2014 |
| Parallel evolution in the emergence of highly pathogenic avian influenza A viruses M Escalera-Zamudio, M Golden, B Gutiérrez, J Thézé, JR Keown, ... Nature Communications 11 (1), 5511, 2020 | 35 | 2020 |
| Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α JR Keown, JX Yang, J Douglas, DC Goldstone Scientific reports 6 (1), 26837, 2016 | 35 | 2016 |
| Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ... Database 2019, 2019 | 34 | 2019 |
| A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family Y Sun, JR Keown, MM Black, C Raclot, N Demarais, D Trono, P Turelli, ... Journal of molecular biology 431 (14), 2511-2527, 2019 | 28 | 2019 |
| The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases J Pinheiro, J Biboy, W Vollmer, RP Hirt, JR Keown, A Artuyants, MM Black, ... MBio 9 (6), 10.1128/mbio. 01784-18, 2018 | 25 | 2018 |
| A structural understanding of influenza virus genome replication Z Zhu, E Fodor, JR Keown Trends in microbiology 31 (3), 308-319, 2023 | 22 | 2023 |
| Design, synthesis, and biological evaluation of novel indoles targeting the influenza PB2 cap binding region DC McGowan, W Balemans, W Embrechts, M Motte, JR Keown, C Buyck, ... Journal of medicinal chemistry 62 (21), 9680-9690, 2019 | 22 | 2019 |
| Crystal structure of the Trim5α Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface JR Keown, DC Goldstone Journal of structural biology 195 (3), 282-285, 2016 | 21 | 2016 |
| Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases AP Walker, H Fan, JR Keown, V Margitich, JM Grimes, E Fodor, ... bioRxiv, 2020 | 20 | 2020 |
| The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a H Veler, H Fan, JR Keown, J Sharps, M Fournier, JM Grimes, E Fodor Journal of Virology 96 (5), e01979-21, 2022 | 14 | 2022 |
| Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies JR Keown, Z Zhu, L Carrique, H Fan, AP Walker, I Serna Martin, E Pardon, ... Nature communications 13 (1), 251, 2022 | 14 | 2022 |
Jonathan GrimesOxford University and Diamond Light SourceVerified email at strubi.ox.ac.uk
