Targeting mitochondrial glutaminase activity inhibits oncogenic transformation JB Wang, JW Erickson, R Fuji, S Ramachandran, P Gao, R Dinavahi, ... Cancer cell 18 (3), 207-219, 2010 | 967 | 2010 |
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 P Cherepanov, ALB Ambrosio, S Rahman, T Ellenberger, A Engelman Proceedings of the National Academy of Sciences 102 (48), 17308-17313, 2005 | 487 | 2005 |
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism A Cassago, APS Ferreira, IM Ferreira, C Fornezari, ERM Gomes, ... Proceedings of the National Academy of Sciences 109 (4), 1092-1097, 2012 | 327 | 2012 |
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 RS Redis, LE Vela, W Lu, JF de Oliveira, C Ivan, C Rodriguez-Aguayo, ... Molecular cell 61 (4), 520-534, 2016 | 182 | 2016 |
Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function AS Nascimento, SMG Dias, FM Nunes, R Aparício, ALB Ambrosio, ... Journal of molecular biology 360 (3), 586-598, 2006 | 136 | 2006 |
The molecular basis for the regulation of the cap-binding complex by the importins SMG Dias, KF Wilson, KS Rojas, ALB Ambrosio, RA Cerione Nature Structural & Molecular Biology 16 (9), 930-937, 2009 | 109 | 2009 |
Active Glutaminase C self-assembles into a supra-tetrameric oligomer which can be disrupted by an allosteric inhibitor. APS Ferreira, A Cassago, KA Goncalves, MM Dias, D Adamoski, ... Journal of Biological Chemistry, jbc. M113. 501346, 2013 | 97 | 2013 |
A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change ALB Ambrosio, MC Nonato, HSS de Araújo, R Arni, RJ Ward, CL Ownby, ... Journal of Biological Chemistry 280 (8), 7326-7335, 2005 | 90 | 2005 |
Ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-activated receptor γ ALB Ambrosio, SMG Dias, I Polikarpov, RB Zurier, SH Burstein, ... Journal of Biological Chemistry 282 (25), 18625-18633, 2007 | 87 | 2007 |
The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: insights for a new classification of snake venom metalloprotease subgroups JRC Muniz, ALB Ambrosio, HS Selistre-de-Araujo, MR Cominetti, ... Toxicon 52 (7), 807-816, 2008 | 76 | 2008 |
Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization MRO Barsottini, JF de Oliveira, D Adamoski, PJPL Teixeira, PFV do Prado, ... Molecular Plant-Microbe Interactions, 2013 | 65 | 2013 |
GLS2 is protumorigenic in breast cancers MM Dias, D Adamoski, LM Dos Reis, CFR Ascenção, KRS de Oliveira, ... Oncogene 39 (3), 690-702, 2019 | 58 | 2019 |
Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter RSK Nagampalli, JEN Quesñay, D Adamoski, Z Islam, J Birch, ... Scientific reports 8 (1), 3510, 2018 | 50 | 2018 |
The crystal structure of necrosis-and ethylene-inducing protein 2 from the causal agent of cacao’s Witches’ Broom disease reveals key elements for its activity G Zaparoli, MRO Barsottini, JF de Oliveira, F Dyszy, PJPL Teixeira, ... Biochemistry 50 (45), 9901-9910, 2011 | 46 | 2011 |
Crystallographic Structure of Phosphofructokinase-2 from Escherichia coli in Complex with Two ATP Molecules. Implications for Substrate Inhibition R Cabrera, ALB Ambrosio, RC Garratt, V Guixé, J Babul Journal of molecular biology 383 (3), 588-602, 2008 | 37 | 2008 |
FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes AC Cardoso, AHM Pereira, ALB Ambrosio, SR Consonni, RR de Oliveira, ... Structure 24 (8), 1301-1310, 2016 | 35 | 2016 |
The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats CC Pasquali, Z Islam, D Adamoski, IM Ferreira, RD Righeto, J Bettini, ... Journal of Biological Chemistry 292 (27), 11572-11585, 2017 | 34 | 2017 |
A redox 2-Cys mechanism regulates the catalytic activity of divergent cyclophilins BM Campos, ML Sforça, ALB Ambrosio, MN Domingues, ... Plant physiology 162 (3), 1311-1323, 2013 | 28 | 2013 |
UV 254 nm is more efficient than UV 222 nm in inactivating SARS-CoV-2 present in human saliva R Sesti-Costa, C von Zuben Negrão, JF Shimizu, A Nagai, RSN Tavares, ... Photodiagnosis and Photodynamic Therapy 39, 103015, 2022 | 26 | 2022 |
Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α AM Fala, JF Oliveira, D Adamoski, JA Aricetti, MM Dias, MVB Dias, ... Scientific reports 5 (1), 12698, 2015 | 24 | 2015 |