| LRRK2 secretion in exosomes is regulated by 14-3-3 KB Fraser, MS Moehle, JPL Daher, PJ Webber, JY Williams, CA Stewart, ... Human molecular genetics 22 (24), 4988-5000, 2013 | 177 | 2013 |
| Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants PYS Lam, CG Clark, R Li, DJP Pinto, MJ Orwat, RA Galemmo, JM Fevig, ... Journal of medicinal chemistry 46 (21), 4405-4418, 2003 | 120 | 2003 |
| Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment BY Owusu, R Galemmo, J Janetka, L Klampfer Cancers 9 (4), 35, 2017 | 118 | 2017 |
| Nitrogen containing heteroaromatics with ortho-substituted P1's as factor Xa inhibitors RA Galemmo Jr, LL Bostrom, DJP Pinto, KA Rossi US Patent 6,548,525, 2003 | 114 | 2003 |
| Inhibitors of factor Xa with a neutral P1 specificity group RA Galemmo Jr, C Dominguez, JM Fevig, Q Han, PY Lam, DJP Pinto, ... US Patent 5,998,424, 1999 | 113 | 1999 |
| Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2‘-(aminosulfonyl)[1,1‘-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a Potent … JR Pruitt, DJP Pinto, RA Galemmo, RS Alexander, KA Rossi, BL Wells, ... Journal of medicinal chemistry 46 (25), 5298-5315, 2003 | 93 | 2003 |
| Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives AC Maroney, JJ Marugan, TM Mezzasalma, AN Barnakov, TA Garrabrant, ... Biochemistry 45 (17), 5678-5685, 2006 | 79 | 2006 |
| Improved solution-and solid-phase preparation of hydroxamic acids from esters CY Ho, E Strobel, J Ralbovsky, RA Galemmo The Journal of organic chemistry 70 (12), 4873-4875, 2005 | 79 | 2005 |
| The synthesis and SAR of 2-amino-pyrrolo [2, 3-d] pyrimidines: a new class of Aurora-A kinase inhibitors KJ Moriarty, HK Koblish, T Garrabrant, J Maisuria, E Khalil, F Ali, ... Bioorganic & medicinal chemistry letters 16 (22), 5778-5783, 2006 | 76 | 2006 |
| Quinoline derivatives and use thereof as antagonists of leukotriene D4 FC Huang, RA Galemmo Jr, HF Campbell US Patent 4,920,132, 1990 | 76 | 1990 |
| Studies with an orally bioavailable αV integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in … RJ Santulli, WA Kinney, S Ghosh, BL DeCorte, L Liu, RWA Tuman, Z Zhou, ... Journal of Pharmacology and Experimental Therapeutics 324 (3), 894-901, 2008 | 73 | 2008 |
| Quinoline derivatives and use thereof as antagonists of leukotriene D4 FC Huang, RA Galemmo Jr, HF Campbell US Patent 4,920,131, 1990 | 71 | 1990 |
| Quinoline derivatives and use thereof as antagonists of leukotriene d4 FC Huang, RA Galemmo Jr, HF Campbell US Patent 4,918,081, 1990 | 66 | 1990 |
| Inhibitors of factor Xa with a neutral P1 specificity group RA Galemmo Jr, C Dominguez, JM Fevig, Q Han, PY Lam, DJP Pinto, ... US Patent 6,403,620, 2002 | 63 | 2002 |
| 1-[3-Aminobenzisoxazol-5′-yl]-3-trifluoromethyl-6-[2′-(3-(R)-hydroxy-N-pyrrolidinyl) methyl-[1, 1′]-biphen-4-yl]-1, 4, 5, 6-tetrahydropyrazolo-[3, 4-c]-pyridin-7-one (BMS … DJP Pinto, MJ Orwat, ML Quan, Q Han, RA Galemmo Jr, E Amparo, ... Bioorganic & medicinal chemistry letters 16 (15), 4141-4147, 2006 | 62 | 2006 |
| Inhibitors of factor Xa with a neutral P1 specificity group RA Galemmo Jr, C Dominguez, JM Fevig, Q Han, PY Lam, DJP Pinto, ... US Patent 6,602,895, 2003 | 57 | 2003 |
| Triazolopyridazines as kinase modulators T Lu, R Alexander, RW Connors, MD Cummings, RA Galemmo, ... US Patent 8,030,305, 2011 | 56 | 2011 |
| Quinoline derivatives and use thereof as antagonists of leukotriene D4 FC Huang, RA Galemmo Jr, HF Campbell US Patent 4,920,130, 1990 | 56 | 1990 |
| Selective and brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) inhibitors that reduce α‐synuclein phosphorylation in rat brain DL Aubele, RK Hom, M Adler, RA Galemmo Jr, S Bowers, AP Truong, ... ChemMedChem 8 (8), 1295-1313, 2013 | 53 | 2013 |
| Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors Q Han, C Dominguez, PFW Stouten, JM Park, DE Duffy, RA Galemmo, ... Journal of medicinal chemistry 43 (23), 4398-4415, 2000 | 53 | 2000 |
Karen RossiBristol-Myers Squibb, Dupont Pharmaceuticals, DuPont MerckVerified email at bms.com
