Adrian Hobbs
Adrian Hobbs
Professor of Cardiovascular Pharmacology, Barts & The London School of Medicine
Verified email at - Homepage
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Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite
AJ Webb, N Patel, S Loukogeorgakis, M Okorie, Z Aboud, S Misra, ...
Hypertension 51 (3), 784-790, 2008
Inhibition of nitric oxide synthase as a potential therapeutic target
AJ Hobbs, A Higgs, S Moncada
Annual review of pharmacology and toxicology 39 (1), 191-220, 1999
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO
V Kapil, AB Milsom, M Okorie, S Maleki-Toyserkani, F Akram, F Rehman, ...
Hypertension 56 (2), 274-281, 2010
Soluble guanylate cyclase: the forgotten sibling
AJ Hobbs
Trends in pharmacological sciences 18 (4), 484-491, 1997
Biphasic regulation of NF-κB activity underlies the pro-and anti-inflammatory actions of nitric oxide
L Connelly, M Palacios-Callender, C Ameixa, S Moncada, AJ Hobbs
The Journal of Immunology 166 (6), 3873-3881, 2001
Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor
SD Chauhan, H Nilsson, A Ahluwalia, AJ Hobbs
Proceedings of the National Academy of Sciences 100 (3), 1426-1431, 2003
Formation of free nitric oxide from L-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase
AJ Hobbs, JM Fukuto, LJ Ignarro
Proceedings of the National Academy of Sciences 91 (23), 10992-10996, 1994
Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility
K Ono, T Akaike, T Sawa, Y Kumagai, DA Wink, DJ Tantillo, AJ Hobbs, ...
Free Radical Biology and Medicine 77, 82-94, 2014
l‐NG‐nitro arginine inhibits non‐adrenergic, non‐cholinergic relaxations of guinea‐pig isolated tracheal smooth muscle
JF Tucker, SR Brave, L Charalambous, AJ Hobbs, A Gibson
British journal of pharmacology 100 (4), 663-664, 1990
Effects of low-dose aspirin on acute inflammatory responses in humans
T Morris, M Stables, A Hobbs, P de Souza, P Colville-Nash, T Warner, ...
The Journal of Immunology 183 (3), 2089-2096, 2009
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension
GP Diller, S van Eijl, DO Okonko, LS Howard, O Ali, T Thum, SJ Wort, ...
Circulation 117 (23), 3020-3030, 2008
The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO
N Paolocci, MI Jackson, BE Lopez, K Miranda, CG Tocchetti, DA Wink, ...
Pharmacology & therapeutics 113 (2), 442-458, 2007
The concise guide to pharmacology 2017/18: overview
SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ...
British journal of pharmacology 174, S1-S16, 2017
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the …
RS Scotland, M Madhani, S Chauhan, S Moncada, J Andresen, H Nilsson, ...
Circulation 111 (6), 796-803, 2005
Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
A Ahluwalia, P Foster, RS Scotland, PG McLean, A Mathur, M Perretti, ...
Proceedings of the National Academy of Sciences 101 (5), 1386-1391, 2004
l‐NG‐monomethyl arginine and l‐NG‐nitro arginine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscle
A Gibson, S Mirzazadeh, AJ Hobbs, PK Moore
British journal of pharmacology 99 (3), 602-606, 1990
NO-independent, haem-dependent soluble guanylate cyclase stimulators
JP Stasch, AJ Hobbs
cGMP: Generators, Effectors and Therapeutic Implications, 277-308, 2009
[13] Nitric oxide-cyclic GMP signal transduction system
AJ Hobbs, LJ Ignarro
Methods in enzymology 269, 134-148, 1996
Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential
SM Ghosh, V Kapil, I Fuentes-Calvo, KJ Bubb, V Pearl, AB Milsom, ...
Hypertension 61 (5), 1091-1102, 2013
Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase
AJ Webb, AB Milsom, KS Rathod, WL Chu, S Qureshi, MJ Lovell, ...
Circulation research 103 (9), 957-964, 2008
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