An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ... American journal of respiratory cell and molecular biology 56 (5), 667-679, 2017 | 336 | 2017 |
TGF-β activation and lung fibrosis AL Tatler, G Jenkins Proceedings of the American Thoracic Society 9 (3), 130-136, 2012 | 282 | 2012 |
PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy G Osman, J Rodriguez, SY Chan, J Chisholm, G Duncan, N Kim, AL Tatler, ... Journal of controlled release 285, 35-45, 2018 | 190 | 2018 |
COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts AE John, C Joseph, G Jenkins, AL Tatler Immunological reviews 302 (1), 228-240, 2021 | 186 | 2021 |
Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma AL Tatler, AE John, L Jolly, A Habgood, J Porte, C Brightling, AJ Knox, ... The Journal of Immunology 187 (11), 6094-6107, 2011 | 154 | 2011 |
Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis AE John, JC Luckett, AL Tatler, RO Awais, A Desai, A Habgood, ... Journal of Nuclear Medicine 54 (12), 2146-2152, 2013 | 116 | 2013 |
Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling PB Noble, CD Pascoe, B Lan, S Ito, LEM Kistemaker, AL Tatler, T Pera, ... Pulmonary pharmacology & therapeutics 29 (2), 96-107, 2014 | 107 | 2014 |
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response N Bedke, D Sammut, B Green, V Kehagia, P Dennison, G Jenkins, ... Public Library of Science 7 (9), e44580, 2012 | 96 | 2012 |
ATS assembly on respiratory cell and molecular biology. An Official American Thoracic Society Workshop Report: use of animal models for the preclinical assessment of potential … RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ... Am J Respir Cell Mol Biol 56 (5), 667-679, 2017 | 84 | 2017 |
Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation L Jolly, A Stavrou, G Vanderstoken, VA Meliopoulos, A Habgood, ... Journal of Biological Chemistry 289 (51), 35246-35263, 2014 | 69 | 2014 |
CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET RL Clifford, JK Patel, AE John, AL Tatler, L Mazengarb, CE Brightling, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (9 …, 2015 | 67 | 2015 |
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices AL Tatler, J Barnes, A Habgood, A Goodwin, RJ McAnulty, G Jenkins Thorax 71 (6), 565-567, 2016 | 64 | 2016 |
Amplification of TGFβ induced ITGB6 gene transcription may promote pulmonary fibrosis AL Tatler, AT Goodwin, O Gbolahan, G Saini, J Porte, AE John, RL Clifford, ... PloS one 11 (8), e0158047, 2016 | 48 | 2016 |
Tryptase activates TGFβ in human airway smooth muscle cells via direct proteolysis AL Tatler, J Porte, A Knox, G Jenkins, L Pang Biochemical and biophysical research communications 370 (2), 239-242, 2008 | 45 | 2008 |
Pathobiology of airway remodeling in asthma: the emerging role of integrins C Joseph, AL Tatler Journal of Asthma and Allergy, 595-610, 2022 | 44 | 2022 |
β-Tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2–independent mechanism CS Mullan, M Riley, D Clarke, A Tatler, A Sutcliffe, AJ Knox, L Pang American Journal of Respiratory Cell and Molecular Biology 38 (5), 600-608, 2008 | 41 | 2008 |
Reduced ets domain-containing protein Elk1 promotes pulmonary fibrosis via increased integrin αvβ6 expression AL Tatler, A Habgood, J Porte, AE John, A Stavrou, E Hodge, ... Journal of Biological Chemistry 291 (18), 9540-9553, 2016 | 40 | 2016 |
Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema AE John, MR Wilson, A Habgood, J Porte, AL Tatler, A Stavrou, G Miele, ... Science signaling 9 (451), ra104-ra104, 2016 | 30 | 2016 |
A theoretical model of inflammation-and mechanotransduction-driven asthmatic airway remodelling MR Hill, CJ Philp, CK Billington, AL Tatler, SR Johnson, RD O’Dea, ... Biomechanics and Modeling in Mechanobiology 17, 1451-1470, 2018 | 27 | 2018 |
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis AN Habgood, AL Tatler, J Porte, SM Wahl, GJ Laurent, AE John, ... Laboratory investigation 96 (6), 623-631, 2016 | 24 | 2016 |