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Amanda Tatler
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An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis
RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ...
American journal of respiratory cell and molecular biology 56 (5), 667-679, 2017
3362017
TGF-β activation and lung fibrosis
AL Tatler, G Jenkins
Proceedings of the American Thoracic Society 9 (3), 130-136, 2012
2822012
PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
G Osman, J Rodriguez, SY Chan, J Chisholm, G Duncan, N Kim, AL Tatler, ...
Journal of controlled release 285, 35-45, 2018
1902018
COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts
AE John, C Joseph, G Jenkins, AL Tatler
Immunological reviews 302 (1), 228-240, 2021
1862021
Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma
AL Tatler, AE John, L Jolly, A Habgood, J Porte, C Brightling, AJ Knox, ...
The Journal of Immunology 187 (11), 6094-6107, 2011
1542011
Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis
AE John, JC Luckett, AL Tatler, RO Awais, A Desai, A Habgood, ...
Journal of Nuclear Medicine 54 (12), 2146-2152, 2013
1162013
Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling
PB Noble, CD Pascoe, B Lan, S Ito, LEM Kistemaker, AL Tatler, T Pera, ...
Pulmonary pharmacology & therapeutics 29 (2), 96-107, 2014
1072014
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response
N Bedke, D Sammut, B Green, V Kehagia, P Dennison, G Jenkins, ...
Public Library of Science 7 (9), e44580, 2012
962012
ATS assembly on respiratory cell and molecular biology. An Official American Thoracic Society Workshop Report: use of animal models for the preclinical assessment of potential …
RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ...
Am J Respir Cell Mol Biol 56 (5), 667-679, 2017
842017
Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation
L Jolly, A Stavrou, G Vanderstoken, VA Meliopoulos, A Habgood, ...
Journal of Biological Chemistry 289 (51), 35246-35263, 2014
692014
CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET
RL Clifford, JK Patel, AE John, AL Tatler, L Mazengarb, CE Brightling, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (9 …, 2015
672015
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices
AL Tatler, J Barnes, A Habgood, A Goodwin, RJ McAnulty, G Jenkins
Thorax 71 (6), 565-567, 2016
642016
Amplification of TGFβ induced ITGB6 gene transcription may promote pulmonary fibrosis
AL Tatler, AT Goodwin, O Gbolahan, G Saini, J Porte, AE John, RL Clifford, ...
PloS one 11 (8), e0158047, 2016
482016
Tryptase activates TGFβ in human airway smooth muscle cells via direct proteolysis
AL Tatler, J Porte, A Knox, G Jenkins, L Pang
Biochemical and biophysical research communications 370 (2), 239-242, 2008
452008
Pathobiology of airway remodeling in asthma: the emerging role of integrins
C Joseph, AL Tatler
Journal of Asthma and Allergy, 595-610, 2022
442022
β-Tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2–independent mechanism
CS Mullan, M Riley, D Clarke, A Tatler, A Sutcliffe, AJ Knox, L Pang
American Journal of Respiratory Cell and Molecular Biology 38 (5), 600-608, 2008
412008
Reduced ets domain-containing protein Elk1 promotes pulmonary fibrosis via increased integrin αvβ6 expression
AL Tatler, A Habgood, J Porte, AE John, A Stavrou, E Hodge, ...
Journal of Biological Chemistry 291 (18), 9540-9553, 2016
402016
Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema
AE John, MR Wilson, A Habgood, J Porte, AL Tatler, A Stavrou, G Miele, ...
Science signaling 9 (451), ra104-ra104, 2016
302016
A theoretical model of inflammation-and mechanotransduction-driven asthmatic airway remodelling
MR Hill, CJ Philp, CK Billington, AL Tatler, SR Johnson, RD O’Dea, ...
Biomechanics and Modeling in Mechanobiology 17, 1451-1470, 2018
272018
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis
AN Habgood, AL Tatler, J Porte, SM Wahl, GJ Laurent, AE John, ...
Laboratory investigation 96 (6), 623-631, 2016
242016
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