Targeting mitochondrial glutaminase activity inhibits oncogenic transformation JB Wang, JW Erickson, R Fuji, S Ramachandran, P Gao, R Dinavahi, ... Cancer cell 18 (3), 207-219, 2010 | 968 | 2010 |
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism A Cassago, APS Ferreira, IM Ferreira, C Fornezari, ERM Gomes, ... Proceedings of the National Academy of Sciences 109 (4), 1092-1097, 2012 | 323 | 2012 |
Allele-specific reprogramming of cancer metabolism by the long non-coding RNA CCAT2 RS Redis, LE Vela, W Lu, JF de Oliveira, C Ivan, C Rodriguez-Aguayo, ... Molecular cell 61 (4), 520-534, 2016 | 184 | 2016 |
Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function AS Nascimento, SMG Dias, FM Nunes, R Aparício, ALB Ambrosio, ... Journal of molecular biology 360 (3), 586-598, 2006 | 138 | 2006 |
The molecular basis for the regulation of the cap-binding complex by the importins SMG Dias, KF Wilson, KS Rojas, ALB Ambrosio, RA Cerione Nature structural & molecular biology 16 (9), 930-937, 2009 | 109 | 2009 |
Using microRNA networks to understand cancer M Dragomir, ACP Mafra, SMG Dias, C Vasilescu, GA Calin International journal of molecular sciences 19 (7), 1871, 2018 | 101 | 2018 |
Gaining ligand selectivity in thyroid hormone receptors via entropy L Martínez, AS Nascimento, FM Nunes, K Phillips, R Aparicio, SMG Dias, ... Proceedings of the National Academy of Sciences 106 (49), 20717-20722, 2009 | 101 | 2009 |
Active glutaminase C self-assembles into a supratetrameric oligomer that can be disrupted by an allosteric inhibitor APS Ferreira, A Cassago, K de Almeida Gonçalves, MM Dias, ... Journal of Biological Chemistry 288 (39), 28009-28020, 2013 | 96 | 2013 |
Ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-activated receptor γ ALB Ambrosio, SMG Dias, I Polikarpov, RB Zurier, SH Burstein, ... Journal of Biological Chemistry 282 (25), 18625-18633, 2007 | 89 | 2007 |
Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition–resistant triple-negative breast cancer cells LM Dos Reis, D Adamoski, ROO Souza, CFR Ascenção, KRS De Oliveira, ... Journal of Biological Chemistry 294 (24), 9342-9357, 2019 | 74 | 2019 |
Functional Diversification of Cerato-Platanins in Moniliophthora perniciosa as Seen by Differential Expression and Protein Function Specialization MR de O. Barsottini, JF de Oliveira, D Adamoski, PJPL Teixeira, ... Molecular Plant-Microbe Interactions 26 (11), 1281-1293, 2013 | 65 | 2013 |
Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms L Bleicher, R Aparicio, FM Nunes, L Martinez, SM Gomes Dias, ... BMC structural biology 8, 1-13, 2008 | 64 | 2008 |
GLS2 is protumorigenic in breast cancers MM Dias, D Adamoski, LM Dos Reis, CFR Ascenção, KRS de Oliveira, ... Oncogene 39 (3), 690-702, 2020 | 58 | 2020 |
Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter RSK Nagampalli, JEN Quesñay, D Adamoski, Z Islam, J Birch, ... Scientific reports 8 (1), 3510, 2018 | 51 | 2018 |
The crystal structure of necrosis-and ethylene-inducing protein 2 from the causal agent of cacao’s Witches’ Broom disease reveals key elements for its activity G Zaparoli, MRO Barsottini, JF de Oliveira, F Dyszy, PJPL Teixeira, ... Biochemistry 50 (45), 9901-9910, 2011 | 47 | 2011 |
Structural flexibility in Trypanosoma brucei enolase revealed by X‐ray crystallography and molecular dynamics MVAS Navarro, SM Gomes Dias, LV Mello, MT da Silva Giotto, S Gavalda, ... The FEBS Journal 274 (19), 5077-5089, 2007 | 47 | 2007 |
Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer M Quintero, D Adamoski, LM Reis, CFR Ascenção, KRS Oliveira, ... BMC cancer 17, 1-16, 2017 | 44 | 2017 |
The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats CC Pasquali, Z Islam, D Adamoski, IM Ferreira, RD Righeto, J Bettini, ... Journal of Biological Chemistry 292 (27), 11572-11585, 2017 | 35 | 2017 |
FAK forms a complex with MEF2 to couple biomechanical signaling to transcription in cardiomyocytes AC Cardoso, AHM Pereira, ALB Ambrosio, SR Consonni, RR de Oliveira, ... Structure 24 (8), 1301-1310, 2016 | 35 | 2016 |
New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells CA Ciocan-Cartita, A Jurj, O Zanoaga, R Cojocneanu, LA Pop, ... Journal of Experimental & Clinical Cancer Research 39, 1-16, 2020 | 32 | 2020 |