| Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models MJD Daniels, J Rivers-Auty, T Schilling, NG Spencer, W Watremez, ... Nature communications 7 (1), 12504, 2016 | 400 | 2016 |
| Inflammasomes as therapeutic targets for A lzheimer's disease CS White, CB Lawrence, D Brough, J Rivers‐Auty Brain pathology 27 (2), 223-234, 2017 | 140 | 2017 |
| Boron-based inhibitors of the NLRP3 inflammasome AG Baldwin, J Rivers-Auty, MJD Daniels, CS White, CH Schwalbe, ... Cell Chemical Biology 24 (11), 1321-1335. e5, 2017 | 101 | 2017 |
| Redefining the ancestral origins of the interleukin-1 superfamily J Rivers-Auty, MJD Daniels, I Colliver, DL Robertson, D Brough Nature communications 9 (1), 1156, 2018 | 89 | 2018 |
| Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia J Xu, P Begley, SJ Church, S Patassini, S McHarg, N Kureishy, ... Scientific reports 6 (1), 27524, 2016 | 79 | 2016 |
| Anti-inflammatories in Alzheimer’s disease—potential therapy or spurious correlate? J Rivers-Auty, AE Mather, R Peters, CB Lawrence, D Brough Brain communications 2 (2), fcaa109, 2020 | 74 | 2020 |
| The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes VS Tapia, MJD Daniels, P Palazón-Riquelme, M Dewhurst, NM Luheshi, ... Journal of Biological Chemistry 294 (21), 8325-8335, 2019 | 74 | 2019 |
| Mitochondrial abnormalities and synaptic loss underlie memory deficits seen in mouse models of obesity and Alzheimer’s disease IVA Martins, J Rivers-Auty, SM Allan, CB Lawrence Journal of Alzheimer's Disease 55 (3), 915-932, 2017 | 67 | 2017 |
| Potassium efflux fires the canon: potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways J Rivers‐Auty, D Brough European Journal of Immunology 45 (10), 2758-2761, 2015 | 65 | 2015 |
| The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse AD Ang, J Rivers-Auty, A Hegde, I Ishii, M Bhatia American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (10 …, 2013 | 58 | 2013 |
| ‘Plasticosis’: characterising macro-and microplastic-associated fibrosis in seabird tissues HS Charlton-Howard, AL Bond, J Rivers-Auty, JL Lavers Journal of Hazardous Materials 450, 131090, 2023 | 55 | 2023 |
| Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation J Rivers-Auty, VS Tapia, CS White, MJD Daniels, S Drinkall, PT Kennedy, ... Journal of Neuroscience 41 (13), 3025-3038, 2021 | 53 | 2021 |
| Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming C Hoyle, J Rivers-Auty, E Lemarchand, S Vranic, E Wang, M Buggio, ... ACS nano 12 (12), 11949-11962, 2018 | 48 | 2018 |
| The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies JRJ Rivers, JC Ashton Central Nervous System Agents in Medicinal Chemistry (Formerly Current …, 2010 | 43 | 2010 |
| Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis CE Diamond, KWK Leong, M Vacca, J Rivers-Auty, D Brough, ... Scientific Reports 7 (1), 6861, 2017 | 40 | 2017 |
| The one-two punch of plastic exposure: macro-and micro-plastics induce multi-organ damage in seabirds J Rivers-Auty, AL Bond, ML Grant, JL Lavers Journal of Hazardous Materials 442, 130117, 2023 | 39 | 2023 |
| Hydrogen sulfide as a therapeutic target for inflammation JR Rivers, A Badiei, M Bhatia Expert opinion on therapeutic targets 16 (5), 439-449, 2012 | 38 | 2012 |
| Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality D Angosto-Bazarra, C Alarcón-Vila, L Hurtado-Navarro, MC Baños, ... BMC biology 20 (1), 9, 2022 | 37 | 2022 |
| Plastic debris increases circadian temperature extremes in beach sediments JL Lavers, J Rivers-Auty, AL Bond Journal of Hazardous Materials 416, 126140, 2021 | 37 | 2021 |
| Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke I Rajkovic, R Wong, E Lemarchand, J Rivers-Auty, O Rajkovic, ... Journal of Molecular Medicine 96, 1319-1332, 2018 | 37 | 2018 |
David BroughUniversity of ManchesterVerified email at manchester.ac.uk
