Bacterial methionine biosynthesis MP Ferla, WM Patrick Microbiology 160 (8), 1571-1584, 2014 | 263 | 2014 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 190 | 2022 |
Evolving accelerated amidation by SpyTag/SpyCatcher to analyze membrane dynamics AH Keeble, A Banerjee, MP Ferla, SC Reddington, INAK Anuar, ... Angewandte Chemie International Edition 56 (52), 16521-16525, 2017 | 183 | 2017 |
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 144 | 2021 |
New rRNA Gene-Based Phylogenies of the Alphaproteobacteria Provide Perspective on Major Groups, Mitochondrial Ancestry and Phylogenetic Instability MP Ferla, JC Thrash, SJ Giovannoni, WM Patrick PLoS One 8 (12), e83383, 2013 | 140 | 2013 |
Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics CG Acevedo-Rocha, A Li, L D’Amore, S Hoebenreich, J Sanchis, ... Nature Communications 12 (1), 1621, 2021 | 87 | 2021 |
Eumalacostracan phylogeny and total evidence: limitations of the usual suspects RA Jenner, CN Dhubhghaill, MP Ferla, MA Wills BMC Evolutionary Biology 9, 1-20, 2009 | 82 | 2009 |
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2 S Gahbauer, GJ Correy, M Schuller, MP Ferla, YU Doruk, M Rachman, ... Proceedings of the National Academy of Sciences 120 (2), e2212931120, 2023 | 76 | 2023 |
A fluorescence lifetime-based fibre-optic glucose sensor using glucose/galactose-binding protein T Saxl, F Khan, M Ferla, D Birch, J Pickup Analyst 136 (5), 968-972, 2011 | 72 | 2011 |
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine … H Achdout, A Aimon, E Bar-David, GM Morris BioRxiv, 2020 | 53 | 2020 |
Delineation of dominant and recessive forms of LZTR1‐associated Noonan syndrome AT Pagnamenta, PJ Kaisaki, F Bennett, E Burkitt‐Wright, HC Martin, ... Clinical Genetics 95 (6), 693-703, 2019 | 52 | 2019 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 48 | 2023 |
Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms CF Wright, NM Quaife, L Ramos-Hernández, P Danecek, MP Ferla, ... The American Journal of Human Genetics 108 (6), 1083-1094, 2021 | 48 | 2021 |
DogCatcher allows loop-friendly protein-protein ligation AH Keeble, VK Yadav, MP Ferla, CC Bauer, E Chuntharpursat-Bon, ... Cell chemical biology 29 (2), 339-350. e10, 2022 | 44 | 2022 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 39 | 2020 |
Primordial‐like enzymes from bacteria with reduced genomes MP Ferla, JL Brewster, KR Hall, GB Evans, WM Patrick Molecular Microbiology 105 (4), 508-524, 2017 | 35 | 2017 |
Biallelic PI4KA variants cause neurological, intestinal and immunological disease CG Salter, Y Cai, B Lo, G Helman, H Taylor, A McCartney, JS Leslie, ... Brain 144 (12), 3597-3610, 2021 | 32 | 2021 |
Identification of circulating genomic and metabolic biomarkers in intrahepatic cholangiocarcinoma H Winter, PJ Kaisaki, J Harvey, E Giacopuzzi, MP Ferla, MM Pentony, ... Cancers 11 (12), 1895, 2019 | 29 | 2019 |
An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy AT Pagnamenta, R Kaiyrzhanov, Y Zou, SI Da'as, R Maroofian, ... Brain 144 (2), 584-600, 2021 | 28 | 2021 |
MichelaNglo: sculpting protein views on web pages without coding MP Ferla, AT Pagnamenta, D Damerell, JC Taylor, BD Marsden Bioinformatics 36 (10), 3268-3270, 2020 | 28 | 2020 |