| Clinicopathological and prognostic significance of vascular endothelial growth factors (VEGF)-C and-D and VEGF receptor 3 in invasive breast carcinoma E Mylona, P Alexandrou, A Mpakali, I Giannopoulou, G Liapis, S Markaki, ... European Journal of Surgical Oncology (EJSO) 33 (3), 294-300, 2007 | 119 | 2007 |
| Structural basis for antigenic peptide recognition and processing by endoplasmic reticulum (ER) aminopeptidase 2 A Mpakali, P Giastas, N Mathioudakis, IM Mavridis, E Saridakis, ... Journal of Biological Chemistry 290 (43), 26021-26032, 2015 | 93 | 2015 |
| The role of antigen processing and presentation in cancer and the efficacy of immune checkpoint inhibitor immunotherapy A Mpakali, E Stratikos Cancers 13 (1), 134, 2021 | 92 | 2021 |
| Optimization and structure–activity relationships of phosphinic pseudotripeptide inhibitors of aminopeptidases that generate antigenic peptides P Kokkala, A Mpakali, FX Mauvais, A Papakyriakou, I Daskalaki, ... Journal of Medicinal Chemistry 59 (19), 9107-9123, 2016 | 74 | 2016 |
| Crystal structure of insulin-regulated aminopeptidase with bound substrate analogue provides insight on antigenic epitope precursor recognition and processing A Mpakali, E Saridakis, K Harlos, Y Zhao, A Papakyriakou, P Kokkala, ... The Journal of Immunology 195 (6), 2842-2851, 2015 | 54 | 2015 |
| Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1 P Giastas, A Mpakali, A Papakyriakou, A Lelis, P Kokkala, M Neu, ... Proceedings of the National Academy of Sciences 116 (52), 26709-26716, 2019 | 47 | 2019 |
| Ligand-induced conformational change of insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity A Mpakali, E Saridakis, K Harlos, Y Zhao, P Kokkala, D Georgiadis, ... Journal of Medicinal Chemistry 60 (7), 2963-2972, 2017 | 44 | 2017 |
| Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1) D Koumantou, E Barnea, A Martin-Esteban, Z Maben, A Papakyriakou, ... Cancer Immunology, Immunotherapy 68, 1245-1261, 2019 | 42 | 2019 |
| Inhibitors of ER aminopeptidase 1 and 2: from design to clinical application D Georgiadis, A Mpakali, D Koumantou, E Stratikos Current medicinal chemistry 26 (15), 2715-2729, 2019 | 42 | 2019 |
| Critical role of interdomain interactions in the conformational change and catalytic mechanism of endoplasmic reticulum aminopeptidase 1 A Stamogiannos, Z Maben, A Papakyriakou, A Mpakali, P Kokkala, ... Biochemistry 56 (10), 1546-1558, 2017 | 37 | 2017 |
| Dnmt3a1 upregulates transcription of distinct genes and targets chromosomal gene clusters for epigenetic silencing in mouse embryonic stem cells AG Kotini, A Mpakali, T Agalioti Molecular and Cellular Biology, 2011 | 36 | 2011 |
| Generation of SARS-CoV-2 S1 spike glycoprotein putative antigenic epitopes in vitro by intracellular aminopeptidases G Stamatakis, M Samiotaki, A Mpakali, G Panayotou, E Stratikos Journal of Proteome Research 19 (11), 4398-4406, 2020 | 24 | 2020 |
| Molecular pathways for antigenic peptide generation by ER aminopeptidase 1 A Mpakali, Z Maben, LJ Stern, E Stratikos Molecular immunology 113, 50-57, 2019 | 23 | 2019 |
| A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1 G Mavridis, R Arya, A Domnick, J Zoidakis, M Makridakis, A Vlahou, ... Journal of Biological Chemistry 295 (21), 7193-7210, 2020 | 22 | 2020 |
| Crystal structures of ERAP2 complexed with inhibitors reveal pharmacophore requirements for optimizing inhibitor potency A Mpakali, P Giastas, R Deprez-Poulain, A Papakyriakou, D Koumantou, ... ACS Medicinal Chemistry Letters 8 (3), 333-337, 2017 | 21 | 2017 |
| Structural basis of inhibition of insulin-regulated aminopeptidase by a macrocyclic peptidic inhibitor A Mpakali, E Saridakis, P Giastas, Z Maben, LJ Stern, M Larhed, ... ACS medicinal chemistry letters 11 (7), 1429-1434, 2020 | 19 | 2020 |
| Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-Amino Acid Derivatives of Bestatin D Vourloumis, I Mavridis, A Athanasoulis, I Temponeras, D Koumantou, ... Journal of medicinal chemistry 65 (14), 10098-10117, 2022 | 11 | 2022 |
| Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis V Camberlein, C Fléau, P Sierocki, L Li, R Gealageas, D Bosc, ... Angewandte Chemie 134 (39), e202203560, 2022 | 9 | 2022 |
| Endoplasmic reticulum aminopeptidase 1 polymorphism Ile276Met is associated with atopic dermatitis and affects the generation of an HLA‐C associated antigenic epitope in vitro W Niepiekło‐Miniewska, A Mpakali, E Stratikos, Ł Matusiak, J Narbutt, ... Journal of the European Academy of Dermatology and Venereology 33 (5), 906-911, 2019 | 9 | 2019 |
| A Carbodiimide-Mediated P–C Bond-Forming Reaction: Mild Amidoalkylation of P-Nucleophiles by Boc-Aminals P Kokkala, T Rajeshkumar, A Mpakali, E Stratikos, KD Vogiatzis, ... Organic Letters 23 (5), 1726-1730, 2021 | 8 | 2021 |
