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Kasper Runager
Kasper Runager
PhD in protein chemistry
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Year
Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp
K Runager, RV Basaiawmoit, T Deva, M Andreasen, Z Valnickova, ...
Journal of biological chemistry 286 (7), 4951-4958, 2011
652011
Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene
H Karring, K Runager, IB Thøgersen, GK Klintworth, P Højrup, JJ Enghild
Experimental eye research 96 (1), 163-170, 2012
592012
Focus on molecules: Transforming growth factor beta induced protein (TGFBIp)
K Runager, JJ Enghild, GK Klintworth
Experimental eye research 87 (4), 298, 2008
532008
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural …
J Underhaug, H Koldsø, K Runager, JT Nielsen, CS Sørensen, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (12), 2812-2822, 2013
462013
Proteomics of Fuchs’ endothelial corneal dystrophy support that the extracellular matrix of Descemet’s membrane is disordered
ET Poulsen, TF Dyrlund, K Runager, C Scavenius, TP Krogager, P Højrup, ...
Journal of proteome research 13 (11), 4659-4667, 2014
402014
Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits
H Karring, ET Poulsen, K Runager, IB Thøgersen, GK Klintworth, P Højrup, ...
Molecular vision 19, 861, 2013
392013
Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging
H Karring, K Runager, Z Valnickova, IB Thøgersen, T Møller-Pedersen, ...
Experimental eye research 90 (1), 57-62, 2010
372010
Molecular imprinting of complex matrices at localized surface plasmon resonance biosensors for screening of global interactions of polyphenols and proteins
JRL Guerreiro, VE Bochenkov, K Runager, H Aslan, M Dong, JJ Enghild, ...
ACS Sensors 1 (3), 258-264, 2016
312016
Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene
ET Poulsen, K Runager, MW Risør, TF Dyrlund, C Scavenius, H Karring, ...
PROTEOMICS–Clinical Applications 8 (3-4), 168-177, 2014
282014
Proteomic profiling of TGFBI‐null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI‐linked corneal dystrophies
ET Poulsen, K Runager, NS Nielsen, MV Lukassen, K Thomsen, P Snider, ...
The FEBS journal 285 (1), 101-114, 2018
272018
Structural and functional implications of human transforming growth factor β-induced protein, TGFBIp, in corneal dystrophies
R García-Castellanos, NS Nielsen, K Runager, IB Thøgersen, ...
Structure 25 (11), 1740-1750. e2, 2017
262017
The insoluble TGFBIp fraction of the cornea is covalently linked via a disulfide bond to type XII collagen
K Runager, GK Klintworth, H Karring, JJ Enghild
Biochemistry 52 (16), 2821-2827, 2013
252013
Fibril core of transforming growth factor beta-induced protein (TGFBIp) facilitates aggregation of corneal TGFBIp
CS Sørensen, K Runager, C Scavenius, MM Jensen, NS Nielsen, ...
Biochemistry 54 (19), 2943-2956, 2015
242015
Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple …
M Andreasen, SB Nielsen, K Runager, G Christiansen, NC Nielsen, ...
Journal of Biological Chemistry 287 (41), 34730-34742, 2012
242012
SAXS models of TGFBIp reveal a trimeric structure and show that the overall shape is not affected by the Arg124His mutation
RV Basaiawmoit, CLP Oliveira, K Runager, CS Sørensen, MA Behrens, ...
Journal of molecular biology 408 (3), 503-513, 2011
242011
Targeting O-glycosyltransferase (OGT) to promote healing of diabetic skin wounds
K Runager, M Bektas, P Berkowitz, DS Rubenstein
Journal of Biological Chemistry 289 (9), 5462-5466, 2014
232014
Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior
YY Amin, K Runager, F Simoes, A Celiz, V Taresco, R Rossi, JJ Enghild, ...
Advanced Materials, 2015
212015
The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus
JH Mikkelsen, K Runager, CBF Andersen
Journal of Biological Chemistry 295 (7), 1781-1791, 2020
202020
Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor β-induced protein (TGFBIp)
K Runager, R Garcia-Castellanos, Z Valnickova, T Kristensen, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
182009
Nanopattern gradients for cell studies fabricated using hole-mask colloidal lithography
T Bøggild, K Runager, DS Sutherland
ACS Applied Materials & Interfaces 8 (24), 14975-14979, 2016
152016
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