Glucagon-like peptide-1 and its class BG protein–coupled receptors: a long march to therapeutic successes C De Graaf, D Donnelly, D Wootten, J Lau, PM Sexton, LJ Miller, JM Ahn, ... Pharmacological reviews 68 (4), 954-1013, 2016 | 304 | 2016 |
Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 131 | 2020 |
Toward a structural understanding of class B GPCR peptide binding and activation YL Liang, MJ Belousoff, P Zhao, C Koole, MM Fletcher, TT Truong, ... Molecular cell 77 (3), 656-668. e5, 2020 | 95 | 2020 |
Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity … YL Liang, MJ Belousoff, MM Fletcher, X Zhang, M Khoshouei, G Deganutti, ... ACS pharmacology & translational science 3 (2), 263-284, 2020 | 74 | 2020 |
Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists MM Fletcher, ML Halls, P Zhao, L Clydesdale, A Christopoulos, ... Biochemical Pharmacology 156, 406-419, 2018 | 49 | 2018 |
Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure–activity relationships for amylin receptor agonism R Kowalczyk, MA Brimble, Y Tomabechi, AJ Fairbanks, M Fletcher, ... Organic & Biomolecular Chemistry 12 (41), 8142-8151, 2014 | 44 | 2014 |
A structural basis for amylin receptor phenotype J Cao, MJ Belousoff, YL Liang, RM Johnson, TM Josephs, MM Fletcher, ... Science 375 (6587), eabm9609, 2022 | 34 | 2022 |
The complexity of signalling mediated by the glucagon-like peptide-1 receptor MM Fletcher, ML Halls, A Christopoulos, PM Sexton, D Wootten Biochemical Society Transactions 44 (2), 582-588, 2016 | 34 | 2016 |
AM833 is a novel agonist of calcitonin family G protein–coupled receptors: pharmacological comparison with six selective and nonselective agonists MM Fletcher, P Keov, TT Truong, G Mennen, CA Hick, P Zhao, ... Journal of Pharmacology and Experimental Therapeutics 377 (3), 417-440, 2021 | 33 | 2021 |
Molecular insights into peptide agonist engagement with the PTH receptor BP Cary, EJ Gerrard, MJ Belousoff, MM Fletcher, Y Jiang, IC Russell, ... Structure 31 (6), 668-676. e5, 2023 | 6 | 2023 |
Understanding VPAC receptor family peptide binding and selectivity SJ Piper, G Deganutti, J Lu, P Zhao, YL Liang, Y Lu, MM Fletcher, ... Nature Communications 13 (1), 7013, 2022 | 4 | 2022 |
Structural insight into selectivity of amylin and calcitonin receptor agonists J Cao, MJ Belousoff, E Gerrard, R Danev, MM Fletcher, E Dal Maso, ... Nature Chemical Biology 20 (2), 162-169, 2024 | 2 | 2024 |
The spatiotemporal control of signalling and trafficking of the GLP-1R MM Fletcher Monash University, 2018 | 1 | 2018 |
Structure-based insight into development of selective and non-selective amylin and calcitonin receptor agonists J Cao, M Belousoff, R Danev, M Fletcher, E dal Maso, H Schreuder, ... | | 2022 |
The Effect of Glycosylation on the Potency of Pramlintide, An Anti-Diabetic Drug M Fletcher, R Kowalczyk, A Fairbanks, M Brimble, DL Hay Pharmacology 2013 (formerly BPS Winter Meeting), 2013 | | 2013 |