Michael D.W. Griffin
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Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret, NTY Lim, ...
Science 359 (6371), 48-55, 2018
Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein AI
YQ Wong, KJ Binger, GJ Howlett, MDW Griffin
Proceedings of the National Academy of Sciences 107 (5), 1977-1982, 2010
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen
BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ...
Journal of Biological Chemistry 283 (41), 27598-27603, 2008
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance
RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard
Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005
Small heat-shock proteins prevent α-synuclein aggregation via transient interactions and their efficacy is affected by the rate of aggregation
D Cox, E Selig, MDW Griffin, JA Carver, H Ecroyd
Journal of Biological Chemistry 291 (43), 22618-22629, 2016
Evolution of quaternary structure in a homotetrameric enzyme
MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ...
Journal of molecular biology 380 (4), 691-703, 2008
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 1-15, 2018
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis
G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ...
Biochemical Journal 411 (2), 351-360, 2008
Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways
MDW Griffin, MLY Mok, LM Wilson, CLL Pham, LJ Waddington, ...
Journal of molecular biology 375 (1), 240-256, 2008
A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis
LM Wilson, YF Mok, KJ Binger, MDW Griffin, HDT Mertens, F Lin, ...
Journal of molecular biology 366 (5), 1639-1651, 2007
Apolipoproteins and amyloid fibril formation in atherosclerosis
CL Teoh, MDW Griffin, GJ Howlett
Protein & cell 2 (2), 116-127, 2011
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate
RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard
Biochimie 86 (4-5), 311-315, 2004
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax
JE Voss, SW Scally, NL Taylor, SC Atkinson, MDW Griffin, CA Hutton, ...
Journal of Biological Chemistry 285 (8), 5188-5195, 2010
Insight into the self-association of key enzymes from pathogenic species
MA Perugini, MDW Griffin, BJ Smith, LE Webb, AJ Davis, E Handman, ...
European Biophysics Journal 34 (5), 469-476, 2005
Avoiding the oligomeric state: αB‐crystallin inhibits fragmentation and induces dissociation of apolipoprotein C‐II amyloid fibrils
KJ Binger, H Ecroyd, S Yang, JA Carver, GJ Howlett, MDW Griffin
The FASEB Journal 27 (3), 1214-1222, 2013
A structural model for apolipoprotein C-II amyloid fibrils: experimental characterization and molecular dynamics simulations
CL Teoh, CLL Pham, N Todorova, A Hung, CN Lincoln, E Lees, YH Lam, ...
Journal of molecular biology 405 (5), 1246-1266, 2011
Methionine oxidation inhibits assembly and promotes disassembly of apolipoprotein C-II amyloid fibrils
KJ Binger, MDW Griffin, GJ Howlett
Biochemistry 47 (38), 10208-10217, 2008
The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
KA Davies, MC Tanzer, MDW Griffin, YF Mok, SN Young, R Qin, EJ Petrie, ...
Cell Death & Differentiation 25 (9), 1567-1580, 2018
The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6
TL Putoczki, RCJ Dobson, MDW Griffin
Acta Crystallographica Section D: Biological Crystallography 70 (9), 2277-2285, 2014
Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
MDW Griffin, JM Billakanti, A Wason, S Keller, HDT Mertens, SC Atkinson, ...
PloS one 7 (7), e40318, 2012
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