Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Cell stem cell 23 (6), 833-849. e5, 2018 | 290 | 2018 |
Therapeutic potential of targeting the oncogenic SHP2 phosphatase LF Zeng, RY Zhang, ZH Yu, S Li, L Wu, AM Gunawan, BS Lane, RS Mali, ... Journal of medicinal chemistry 57 (15), 6594-6609, 2014 | 127 | 2014 |
Single Nucleotide Polymorphism Array Lesions, TET2, DNMT3A, ASXL1 and CBL Mutations Are Present in Systemic Mastocytosis F Traina, V Visconte, AM Jankowska, H Makishima, CL O’Keefe, P Elson, ... Public Library of Science 7 (8), e43090, 2012 | 121 | 2012 |
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL RS Mali, B Ramdas, P Ma, J Shi, V Munugalavadla, E Sims, L Wei, ... Cancer cell 20 (3), 357-369, 2011 | 98 | 2011 |
Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models RS Mali, Q Zhang, RA DeFilippis, A Cavazos, VM Kuruvilla, J Raman, ... Haematologica 106 (4), 1034, 2021 | 91 | 2021 |
The effect of plasminogen activator inhibitor type 1 on apoptosis DJ Schneider, Y Chen, BE Sobel Thrombosis and haemostasis 100 (12), 1037-1040, 2008 | 75 | 2008 |
Regulation of Stat5 by FAK and PAK1 in oncogenic FLT3-and KIT-driven leukemogenesis A Chatterjee, J Ghosh, B Ramdas, RS Mali, H Martin, M Kobayashi, ... Cell reports 9 (4), 1333-1348, 2014 | 61 | 2014 |
Plasminogen activators promote excitotoxicity-induced retinal damage RS Mali, M Cheng, SK Chintala The FASEB journal: official publication of the Federation of American …, 2005 | 60 | 2005 |
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT RS Mali, P Ma, LF Zeng, H Martin, B Ramdas, Y He, E Sims, S Nabinger, ... Blood, The Journal of the American Society of Hematology 120 (13), 2669-2678, 2012 | 57 | 2012 |
Pak and Rac GTPases promote oncogenic KIT–induced neoplasms H Martin, RS Mali, P Ma, A Chatterjee, B Ramdas, E Sims, ... The Journal of clinical investigation 123 (10), 4449-4463, 2013 | 48 | 2013 |
Metabolism of dietary ODAP in humans may be responsible for the low incidence of neurolathyrism MPP Rudra, MR Singh, MA Junaid, P Jyothi, SLN Rao Clinical Biochemistry 37 (4), 318-322, 2004 | 43 | 2004 |
S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance J Ghosh, M Kobayashi, B Ramdas, A Chatterjee, P Ma, RS Mali, ... The Journal of clinical investigation 126 (7), 2621-2625, 2016 | 41 | 2016 |
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53 S Vemula, J Shi, RS Mali, P Ma, Y Liu, P Hanneman, KR Koehler, ... Blood, The Journal of the American Society of Hematology 120 (14), 2868-2878, 2012 | 41 | 2012 |
PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML CB Goodwin, XJ Li, RS Mali, G Chan, M Kang, Z Liu, B Vanhaesebroeck, ... Blood, The Journal of the American Society of Hematology 123 (18), 2838-2842, 2014 | 40 | 2014 |
The transcription factor neural retina leucine zipper (NRL) controls photoreceptor-specific expression of myocyte enhancer factor Mef2c from an alternative promoter H Hao, P Tummala, E Guzman, RS Mali, J Gregorski, A Swaroop, ... Journal of Biological Chemistry 286 (40), 34893-34902, 2011 | 40 | 2011 |
The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor P Ma, RS Mali, V Munugalavadla, S Krishnan, B Ramdas, E Sims, ... Blood, The Journal of the American Society of Hematology 118 (13), 3459-3469, 2011 | 34 | 2011 |
Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation BK Stansfield, WK Bessler, R Mali, JA Mund, BD Downing, R Kapur, ... The American Journal of Pathology 184 (1), 79-85, 2014 | 33 | 2014 |
SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice N Sharma, V Kumar, S Everingham, RS Mali, R Kapur, LF Zeng, ... Molecular and cellular biology 32 (14), 2653-2663, 2012 | 29 | 2012 |
p85α regulates osteoblast differentiation by cross-talking with the MAPK pathway X Wu, S Chen, SA Orlando, J Yuan, ET Kim, V Munugalavadla, RS Mali, ... Journal of Biological Chemistry 286 (15), 13512-13521, 2011 | 28 | 2011 |
Temporal ChIP-on-Chip of RNA-Polymerase-II to detect novel gene activation events during photoreceptor maturation P Tummala, RS Mali, E Guzman, X Zhang, KP Mitton Molecular Vision 16, 252, 2010 | 26 | 2010 |