| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins AM Verhagen, PG Ekert, M Pakusch, J Silke, LM Connolly, GE Reid, ... cell 102 (1), 43-53, 2000 | 3353 | 2000 |
| Programmed anuclear cell death delimits platelet life span KD Mason, MR Carpinelli, JI Fletcher, JE Collinge, AA Hilton, S Ellis, ... Cell 128 (6), 1173-1186, 2007 | 1199 | 2007 |
| HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins AM Verhagen, J Silke, PG Ekert, M Pakusch, H Kaufmann, LM Connolly, ... Journal of Biological Chemistry 277 (1), 445-454, 2002 | 794 | 2002 |
| Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf, PG Ekert, ... Nature 419 (6907), 634-637, 2002 | 719 | 2002 |
| Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia CN Hahn, CE Chong, CL Carmichael, EJ Wilkins, PJ Brautigan, XC Li, ... Nature genetics 43 (10), 1012-1017, 2011 | 682 | 2011 |
| Caspase inhibitors PG Ekert, J Silke, DL Vaux Cell Death & Differentiation 6 (11), 1081-1086, 1999 | 652 | 1999 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 587 | 2014 |
| Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma B Hassannia, B Wiernicki, I Ingold, F Qu, S Van Herck, YY Tyurina, ... The Journal of clinical investigation 128 (8), 3341-3355, 2018 | 474 | 2018 |
| A prospective evaluation of whole-exome sequencing as a first-tier molecular test in infants with suspected monogenic disorders Z Stark, TY Tan, B Chong, GR Brett, P Yap, M Walsh, A Yeung, H Peters, ... Genetics in medicine 18 (11), 1090-1096, 2016 | 398 | 2016 |
| The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease TR Hercus, D Thomas, MA Guthridge, PG Ekert, J King-Scott, MW Parker, ... Blood, The Journal of the American Society of Hematology 114 (7), 1289-1298, 2009 | 353 | 2009 |
| DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9 PG Ekert, J Silke, CJ Hawkins, AM Verhagen, DL Vaux The Journal of cell biology 152 (3), 483-490, 2001 | 269 | 2001 |
| The BH3-only protein bid is dispensable for DNA damage-and replicative stress-induced apoptosis or cell-cycle arrest T Kaufmann, L Tai, PG Ekert, DCS Huang, F Norris, RK Lindemann, ... Cell 129 (2), 423-433, 2007 | 245 | 2007 |
| Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die PG Ekert, SH Read, J Silke, VS Marsden, H Kaufmann, CJ Hawkins, ... The Journal of cell biology 165 (6), 835-842, 2004 | 224 | 2004 |
| The molecular relationships between apoptosis, autophagy and necroptosis N Lalaoui, LM Lindqvist, JJ Sandow, PG Ekert Seminars in cell & developmental biology 39, 63-69, 2015 | 215 | 2015 |
| Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer M Wong, C Mayoh, LMS Lau, DA Khuong-Quang, M Pinese, A Kumar, ... Nature medicine 26 (11), 1742-1753, 2020 | 213 | 2020 |
| Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance J Silke, T Kratina, D Chu, PG Ekert, CL Day, M Pakusch, DCS Huang, ... Proceedings of the National Academy of Sciences 102 (45), 16182-16187, 2005 | 211 | 2005 |
| Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 LA O'Reilly, P Ekert, N Harvey, V Marsden, L Cullen, DL Vaux, G Hacker, ... Cell Death & Differentiation 9 (8), 832-841, 2002 | 208 | 2002 |
| A novel Apaf-1–independent putative caspase-2 activation complex SH Read, BC Baliga, PG Ekert, DL Vaux, S Kumar The Journal of cell biology 159 (5), 739-745, 2002 | 195 | 2002 |
| The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3–and caspase 9–interacting sites J Silke, CJ Hawkins, PG Ekert, J Chew, CL Day, M Pakusch, ... The Journal of cell biology 157 (1), 115-124, 2002 | 187 | 2002 |
| Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes C Oberle, J Huai, T Reinheckel, M Tacke, M Rassner, PG Ekert, ... Cell Death & Differentiation 17 (7), 1167-1178, 2010 | 186 | 2010 |
