| FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension E Spiekerkoetter, X Tian, J Cai, RK Hopper, D Sudheendra, CG Li, ... The Journal of clinical investigation 123 (8), 3600-3613, 2013 | 453 | 2013 |
| BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension I Diebold, JK Hennigs, K Miyagawa, CG Li, NP Nickel, M Kaschwich, ... Cell metabolism 21 (4), 596-608, 2015 | 203 | 2015 |
| Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ... American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015 | 140 | 2015 |
| Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension VA de Jesus Perez, K Yuan, MA Lyuksyutova, F Dewey, ME Orcholski, ... American journal of respiratory and critical care medicine 189 (10), 1260-1272, 2014 | 96 | 2014 |
| Smooth muscle contact drives endothelial regeneration by BMPR2-notch1–mediated metabolic and epigenetic changes K Miyagawa, M Shi, PI Chen, JK Hennigs, Z Zhao, M Wang, CG Li, T Saito, ... Circulation research 124 (2), 211-224, 2019 | 91 | 2019 |
| RNA sequencing analysis detection of a novel pathway of endothelial dysfunction in pulmonary arterial hypertension CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ... American journal of respiratory and critical care medicine 192 (3), 356-366, 2015 | 89 | 2015 |
| Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity S Sa, M Gu, J Chappell, NY Shao, M Ameen, KAT Elliott, D Li, F Grubert, ... American journal of respiratory and critical care medicine 195 (7), 930-941, 2017 | 85 | 2017 |
| PAX Genes in Cancer; Friends or Foes? CG Li, MR Eccles Frontiers in Genetics 3, 6, 2012 | 84 | 2012 |
| Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension PI Chen, A Cao, K Miyagawa, NF Tojais, JK Hennigs, CG Li, NM Sweeney, ... JCI insight 2 (2), 2017 | 83 | 2017 |
| PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein CG Li, JE Nyman, AW Braithwaite, MR Eccles Oncogene 30 (48), 4824-4834, 2011 | 75 | 2011 |
| PPARγ interaction with UBR5/ATMIN promotes DNA repair to maintain endothelial homeostasis CG Li, C Mahon, NM Sweeney, E Verschueren, V Kantamani, D Li, ... Cell reports 26 (5), 1333-1343. e7, 2019 | 67 | 2019 |
| Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ... Circulation 136 (20), 1920-1935, 2017 | 54 | 2017 |
| The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling EJ Moon, SS Mello, CG Li, JT Chi, K Thakkar, JG Kirkland, EL Lagory, ... Nature communications 12 (1), 4308, 2021 | 53 | 2021 |
| PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ... Circulation research 128 (3), 401-418, 2021 | 43 | 2021 |
| ALDH1A3 coordinates metabolism with gene regulation in pulmonary arterial hypertension D Li, NY Shao, JR Moonen, Z Zhao, M Shi, S Otsuki, L Wang, T Nguyen, ... Circulation 143 (21), 2074-2090, 2021 | 42 | 2021 |
| Loss of PPARγ in endothelial cells leads to impaired angiogenesis S Vattulainen-Collanus, O Akinrinade, M Li, M Koskenvuo, CG Li, SP Rao, ... Journal of Cell Science 129 (4), 693-705, 2016 | 42 | 2016 |
| Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans VA de Jesus Perez, K Yuan, ME Orcholski, H Sawada, M Zhao, CG Li, ... Circulation research 111 (12), 1551-1564, 2012 | 31 | 2012 |
| PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression S He, CG Li, L Slobbe, A Glover, E Marshall, BC Baguley, MR Eccles Melanoma Research 21 (1), 24-34, 2011 | 21 | 2011 |
| Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models M Mehibel, Y Xu, CG Li, EJ Moon, KN Thakkar, AN Diep, RK Kim, ... The Journal of clinical investigation 131 (11), 2021 | 19 | 2021 |
| SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma G Kaur, CG Li, A Chantry, C Stayner, J Horsfield, MR Eccles Oncotarget 9 (42), 26852, 2018 | 18 | 2018 |
