Caiyun Grace Li
Caiyun Grace Li
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FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension
E Spiekerkoetter, X Tian, J Cai, RK Hopper, D Sudheendra, CG Li, ...
The Journal of clinical investigation 123 (8), 3600-3613, 2013
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension
I Diebold, JK Hennigs, K Miyagawa, CG Li, NP Nickel, M Kaschwich, ...
Cell metabolism 21 (4), 596-608, 2015
Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling
NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ...
American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015
Smooth muscle contact drives endothelial regeneration by BMPR2-notch1–mediated metabolic and epigenetic changes
K Miyagawa, M Shi, PI Chen, JK Hennigs, Z Zhao, M Wang, CG Li, T Saito, ...
Circulation research 124 (2), 211-224, 2019
Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension
VA de Jesus Perez, K Yuan, MA Lyuksyutova, F Dewey, ME Orcholski, ...
American journal of respiratory and critical care medicine 189 (10), 1260-1272, 2014
RNA sequencing analysis detection of a novel pathway of endothelial dysfunction in pulmonary arterial hypertension
CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ...
American journal of respiratory and critical care medicine 192 (3), 356-366, 2015
Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity
S Sa, M Gu, J Chappell, NY Shao, M Ameen, KAT Elliott, D Li, F Grubert, ...
American journal of respiratory and critical care medicine 195 (7), 930-941, 2017
Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension
PI Chen, A Cao, K Miyagawa, NF Tojais, JK Hennigs, CG Li, NM Sweeney, ...
JCI insight 2 (2), 2017
PAX Genes in Cancer; Friends or Foes?
CG Li, MR Eccles
Frontiers in genetics 3, 6, 2012
PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein
CG Li, JE Nyman, AW Braithwaite, MR Eccles
Oncogene 30 (48), 4824-4834, 2011
PPARγ interaction with UBR5/ATMIN promotes DNA repair to maintain endothelial homeostasis
CG Li, C Mahon, NM Sweeney, E Verschueren, V Kantamani, D Li, ...
Cell reports 26 (5), 1333-1343. e7, 2019
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
EJ Moon, SS Mello, CG Li, JT Chi, K Thakkar, JG Kirkland, EL Lagory, ...
Nature communications 12 (1), 4308, 2021
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension
T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ...
Circulation 136 (20), 1920-1935, 2017
PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension
JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ...
Circulation research 128 (3), 401-418, 2021
ALDH1A3 coordinates metabolism with gene regulation in pulmonary arterial hypertension
D Li, NY Shao, JR Moonen, Z Zhao, M Shi, S Otsuki, L Wang, T Nguyen, ...
Circulation 143 (21), 2074-2090, 2021
Loss of PPARγ in endothelial cells leads to impaired angiogenesis
S Vattulainen-Collanus, O Akinrinade, M Li, M Koskenvuo, CG Li, SP Rao, ...
Journal of Cell Science 129 (4), 693-705, 2016
Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans
VA de Jesus Perez, K Yuan, ME Orcholski, H Sawada, M Zhao, CG Li, ...
Circulation research 111 (12), 1551-1564, 2012
PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression
S He, CG Li, L Slobbe, A Glover, E Marshall, BC Baguley, MR Eccles
Melanoma Research 21 (1), 24-34, 2011
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models
M Mehibel, Y Xu, CG Li, EJ Moon, KN Thakkar, AN Diep, RK Kim, ...
The Journal of clinical investigation 131 (11), 2021
SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma
G Kaur, CG Li, A Chantry, C Stayner, J Horsfield, MR Eccles
Oncotarget 9 (42), 26852, 2018
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